Lecture 9: ILCs and NK Cells

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What is the main difference between Innate Lymphoid Cells (ILCs) and Natural Killer (NK) Cells?

ILCs are antigen-specific, while NK cells are not.

What is the role of cytokines in the activation of Innate Lymphoid Cells (ILCs)?

Cytokines activate ILCs by being secreted from other cells like DCs.

Which statement about Natural Killer (NK) cells is FALSE?

NK cells rely solely on PRRs for activation, unlike other lymphoid cells.

What is the significance of inhibitory receptors on Natural Killer (NK) cells?

Inhibitory receptors prevent the activation of NK cells against healthy cells.

Which type of cells express Pattern Recognition Receptors (PRRs) according to the text?

All types of myeloid white blood cells

How do Innate Lymphoid Cells (ILCs) contribute to defense against specific pathogens?

By secreting cytokines after activation by other immune cells.

Why do Natural Killer (NK) cells require both activating and inhibitory signals for cell killing?

To avoid unnecessary activation against healthy cells.

Which statement accurately describes the presence of Pattern Recognition Receptors (PRRs) in lymphoid cells according to the text?

ILC 1, 2, 3 normally don’t have PRRs

Learn about Innate Lymphoid Cells (ILCs) and Natural Killer (NK) Cells, which share a common progenitor and have important roles in the immune system. Understand the differences between the two types of cells and their functions in mucosal immunity and defense against pathogens.

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