10 Questions
What distinguishes the charged initiator tRNA, Met-tRNAi, in eukaryotes from other Met-tRNAs?
It can bind IFs.
What role does the cap-binding protein (CBP) play in eukaryotic translation initiation?
Facilitates the movement of the ribosome to the AUG start codon.
What is the significance of the 7-methylguanosine cap at the 5′ end of mRNA in eukaryotic translation initiation?
Helps in tracking along the mRNA from 5′ to 3′ direction.
According to Kozak’s rules, what does the consensus sequence 5′-gccRccAUGG-3′ around the AUG start codon indicate?
Efficiency of translation initiation.
How does Met-tRNAi in eukaryotes differ from other Met-tRNAs in terms of binding during translation initiation?
Binds directly to the P site without entering the A site.
During which phase of meiosis do homologous chromosomes pair up, exchange genetic information through crossing over, and condense?
Prophase I
What is the main function of cyclins and cyclin-dependent kinases (CDKs) in cell cycle regulation?
Driving the cell cycle progression
Which stage of meiosis involves the separation of homologous chromosome pairs into two groups, one maternal and one paternal?
Anaphase I
What is the primary goal of the G1 (Gap 1) phase in the cell cycle?
Ensuring proper growth
Which phase of the cell cycle involves DNA synthesis and duplication of chromosomes?
S Phase
This quiz covers the process of initiation of translation in protein synthesis, focusing on the formation of the initiation complex in E.coli involving ribosomes, mRNA template, initiation factors, and initiator tRNA. Topics include the interaction of initiator tRNA with start codons, linking to formylated methionine, and the role of IF-2.
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