Podcast
Questions and Answers
What distinguishes the charged initiator tRNA, Met-tRNAi, in eukaryotes from other Met-tRNAs?
What distinguishes the charged initiator tRNA, Met-tRNAi, in eukaryotes from other Met-tRNAs?
- It cannot bind to the 5′ cap of mRNA.
- It does not require the 60S subunit for translation initiation.
- It binds fMet at the Shine-Dalgarno sequence.
- It can bind IFs. (correct)
What role does the cap-binding protein (CBP) play in eukaryotic translation initiation?
What role does the cap-binding protein (CBP) play in eukaryotic translation initiation?
- Directly binds to the 5′ cap of mRNA.
- Releases dissociated tRNAs from the E site.
- Assists in the deposition of charged tRNA at the Shine-Dalgarno sequence.
- Facilitates the movement of the ribosome to the AUG start codon. (correct)
What is the significance of the 7-methylguanosine cap at the 5′ end of mRNA in eukaryotic translation initiation?
What is the significance of the 7-methylguanosine cap at the 5′ end of mRNA in eukaryotic translation initiation?
- Indicates the first AUG start codon.
- Helps in tracking along the mRNA from 5′ to 3′ direction. (correct)
- It directly binds to IFs for translation initiation.
- Acts as a recognition site for charged initiator tRNA.
According to Kozak’s rules, what does the consensus sequence 5′-gccRccAUGG-3′ around the AUG start codon indicate?
According to Kozak’s rules, what does the consensus sequence 5′-gccRccAUGG-3′ around the AUG start codon indicate?
How does Met-tRNAi in eukaryotes differ from other Met-tRNAs in terms of binding during translation initiation?
How does Met-tRNAi in eukaryotes differ from other Met-tRNAs in terms of binding during translation initiation?
During which phase of meiosis do homologous chromosomes pair up, exchange genetic information through crossing over, and condense?
During which phase of meiosis do homologous chromosomes pair up, exchange genetic information through crossing over, and condense?
What is the main function of cyclins and cyclin-dependent kinases (CDKs) in cell cycle regulation?
What is the main function of cyclins and cyclin-dependent kinases (CDKs) in cell cycle regulation?
Which stage of meiosis involves the separation of homologous chromosome pairs into two groups, one maternal and one paternal?
Which stage of meiosis involves the separation of homologous chromosome pairs into two groups, one maternal and one paternal?
What is the primary goal of the G1 (Gap 1) phase in the cell cycle?
What is the primary goal of the G1 (Gap 1) phase in the cell cycle?
Which phase of the cell cycle involves DNA synthesis and duplication of chromosomes?
Which phase of the cell cycle involves DNA synthesis and duplication of chromosomes?