Podcast
Questions and Answers
Which characteristic of cytokines is described as different cytokines having the same effect?
Which characteristic of cytokines is described as different cytokines having the same effect?
- Antagonism
- Synergy
- Pleiotropism
- Redundancy (correct)
What is the main function of TNF-alpha among the following?
What is the main function of TNF-alpha among the following?
- Inhibit clotting
- Suppress immune response
- Reduce inflammation
- Promote migration of innate cells (correct)
In the context of adaptive immune response, what is the role of fate-specifying cytokines secreted by antigen-presenting cells?
In the context of adaptive immune response, what is the role of fate-specifying cytokines secreted by antigen-presenting cells?
- Activate B cells
- Activate dendritic cells
- Impact the differentiation of T cells (correct)
- Promote antibody production
Which type of immunity is characterized by B cell activation and antibody production?
Which type of immunity is characterized by B cell activation and antibody production?
What is the purpose of macrophage activation in local inflammation?
What is the purpose of macrophage activation in local inflammation?
Which cytokine is involved in therapies targeting Rheumatoid Arthritis and Chron's disease?
Which cytokine is involved in therapies targeting Rheumatoid Arthritis and Chron's disease?
What is the effect of TNF-alpha on blood vessels?
What is the effect of TNF-alpha on blood vessels?
Which type of immune response is mostly directed towards intracellular pathogens and viral infections?
Which type of immune response is mostly directed towards intracellular pathogens and viral infections?
What is the term used to describe two or more cytokines working together to induce an effect?
What is the term used to describe two or more cytokines working together to induce an effect?
In the context of cytokines, what does pleiotropism refer to?
In the context of cytokines, what does pleiotropism refer to?
How do cytokines affect the producing cell?
How do cytokines affect the producing cell?
Which mechanism describes how cytokines affect adjacent cells?
Which mechanism describes how cytokines affect adjacent cells?
Which type of cytokines can move through circulation and bind to distant receptors?
Which type of cytokines can move through circulation and bind to distant receptors?
What is the primary function of cytokines when they are produced due to an inducing stimulus?
What is the primary function of cytokines when they are produced due to an inducing stimulus?
Which group does Interleukins belong to?
Which group does Interleukins belong to?
What is the main consequence of having lots of TNF-alpha in the body?
What is the main consequence of having lots of TNF-alpha in the body?
Which cytokines induce the synthesis and secretion of antimicrobial proteins like Mannose-binding lectin (MBL) and Complement components?
Which cytokines induce the synthesis and secretion of antimicrobial proteins like Mannose-binding lectin (MBL) and Complement components?
Which type of immune response does TNF-alpha stimulate by migrating dendritic cells to lymph nodes and inducing maturation?
Which type of immune response does TNF-alpha stimulate by migrating dendritic cells to lymph nodes and inducing maturation?
What is the main role of c-reactive protein (CRP) in the acute phase response?
What is the main role of c-reactive protein (CRP) in the acute phase response?
Which cytokines are responsible for causing fever by signaling to induce a cascade that leads to a signal to the hypothalamus?
Which cytokines are responsible for causing fever by signaling to induce a cascade that leads to a signal to the hypothalamus?
In the acute phase response, which organ produces c-reactive protein (CRP) and Mannose-binding lectin (MBL)?
In the acute phase response, which organ produces c-reactive protein (CRP) and Mannose-binding lectin (MBL)?
How do inflammatory cytokines impact the bone marrow endothelium?
How do inflammatory cytokines impact the bone marrow endothelium?
Which cells secrete different cytokines that can impact differentiation of T cells?
Which cells secrete different cytokines that can impact differentiation of T cells?
Which of the following best describes the role of cytokines in the body?
Which of the following best describes the role of cytokines in the body?
What is the main outcome of having excessive TNF-alpha in the body leading to sepsis?
What is the main outcome of having excessive TNF-alpha in the body leading to sepsis?
