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Immunosuppressives

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Which of the following immunosuppressives is used for KCS, immune-mediated diseases, primarily atopic dermatitis

Cyclosporin (atopica)

Immunosuppressive commonly used for immune-mediated diseases including (most commonly) IMHA, myasthenia gravis, pemphigus falaceus, and inflammatory bowel disease (vomiting and diarrhea are the most commonly seen side effects)

Mycophenolate (cellcept)

Immunosuppressive commonly used for autoimmune diseases, atopic dermatitis, and pemphigus; ophthalmic form for KCS

Tacrolimus (protopic)

MATCH

Panleukopenia, herpesvirus, calicivirus, rabies = Cat Distemper, adenovirus, parvovirus, rabies = Dog Distemper, rabies = Ferret

  • = -

Match

Incapable of replicating within the body = Killed or inactivated Virulence of pathogen is greatly reduced, still capable of causing an immune response but significantly less virulent (is most used) = Attenuated or modified live Developed by passing a virus through a series of cell cultures or animal models to slightly alter the ability of the virus to recognize its host (can still replicate within the cells of the host, can turn pathogenic and rarely used) = Live Use a carrier such as attenuated virus or bacterium, to introduce microbial DNA to the host, mimics naturally occurring infection and thereby stimulating the immune response in the recipient = Recombinant

Match

Rabies, canine influenza, leptspirosis, Prestige 5 + west nile virus vaccine = Killed or inactivated Canine parvovirus, equine encephalomyelitis, bovine viral diarrhea, Nobivac feline rhinotracheitis = Attenuated or modified live Newcastle disease, Bordetella bronchiseptica = Live R canine distemper virus vaccine, r feline rhinotracheitis, r canine lyme disease = Recombinant vaccine

Match

Used for viruses dangerous to culture in a lab, immunize by injection of DNA-encoded viral antigens = Polynucleotide vaccines Used in cases in which a bacterial toxin would cause harm, toxin is inactivated with formaldehyde and sterile water then developed into a vaccine = Toxoid vaccines Stimulate and immediate immune response to neutralize the antigen, example of passive immunity = Antiserums and antitoxoids Prepared by collecting samples and isolating pathogens from the actual patient that has to be treated = Autogenous vaccines

Match

Bovine herpesvirus, west nile virus, newcastle disease = Polynucleotide vx Tetanus = Toxoid vx Canine melanoma = Autogenous vx Core vx for domestic species = Polyvalent vx

Produced to protect the recipient from multiple pathogens

Polyvalent vx

This quiz assesses your knowledge of immunosuppressive medications used to treat Keratoconjunctivitis Sicca (KCS) and immune-mediated diseases, particularly atopic dermatitis.

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