Immunosuppression vs RASi for IgA Nephropathy
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Questions and Answers

What percentage of patients on immunosuppression + RASi reached clinical remission at trial endpoint?

  • 17% (correct)
  • 22%
  • 5%
  • 28%

How many patients taking immunosuppression had an eGFR decrease of ≥15 mL/min/1.73 m2 at trial endpoint?

  • 22 (correct)
  • 80
  • 82
  • 21

What adverse events were predominantly associated with immunosuppression?

  • Gastrointestinal and respiratory tract infections (correct)
  • Musculoskeletal and urinary tract infections
  • Skin and eye infections
  • Cardiovascular and neurological events

What was the primary renal outcome percentage for patients taking methylprednisolone at trial endpoint?

<p>28.8% (C)</p> Signup and view all the answers

What risk was associated with methylprednisolone compared to placebo?

<p>Increased risk of severe adverse events (D)</p> Signup and view all the answers

How many patients on methylprednisolone developed a severe infection requiring hospitalization despite antibiotic prophylaxis within the first 12 weeks of therapy?

<p>5 (D)</p> Signup and view all the answers

What was the predominant ethnicity of the patient population in the testing for methylprednisolone?

<p>Asian (B)</p> Signup and view all the answers

Was proteinuria reduction still apparent in participants 36 months after randomization?

<p>No, it was no longer apparent (B)</p> Signup and view all the answers

Did many participants continue to gain kidney function over time?

<p>No, they continued to lose kidney function (D)</p> Signup and view all the answers

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