WK 11: Introduction to Autoimmunity and Hypersensitivity
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Questions and Answers

What type of hypersensitivity reaction is associated with an immediate response?

  • Type I (correct)
  • Type II
  • Type IV
  • Type III

    • Which autoimmune disease involves the immune system attacking the myelin sheath of nerve cells?

  • Multiple sclerosis (correct)
  • Grave's disease
  • Type 1 diabetes mellitus
  • Rheumatoid arthritis

    • Which type of hypersensitivity reaction is characterized by immune complex deposition?

  • Type I
  • Type IV
  • Type III (correct)
  • Type II

    • What type of antibody is involved in Type II hypersensitivity reactions?

    <p>IgG</p> Signup and view all the answers

    Autoimmune hemolytic anemia is an example of which type of hypersensitivity reaction?

    <p>Type II</p> Signup and view all the answers

    Which autoimmune disease involves antibodies attacking the acetylcholine receptors at the neuromuscular junction?

    <p>Myasthenia gravis</p> Signup and view all the answers

    What is a hypersensitivity reaction?

    <p>An inappropriate immune response to a harmless substance.</p> Signup and view all the answers

    What type of hypersensitivity reaction is an allergic reaction?

    <p>Type I hypersensitivity</p> Signup and view all the answers

    What is an autoimmune disease?

    <p>A hypersensitivity reaction targeted at the body's own tissues.</p> Signup and view all the answers

    What is an example of a Type A adverse reaction?

    <p>Morphine causing drowsiness.</p> Signup and view all the answers

    What is anaphylaxis?

    <p>A severe allergic reaction with systemic features.</p> Signup and view all the answers

    What is the difference between hypersensitivity and allergy?

    <p>Allergy is a specific type of hypersensitivity reaction.</p> Signup and view all the answers

    What key immune components are involved in type III hypersensitivity reactions?

    <p>IgM and IgG antibodies</p> Signup and view all the answers

    Which type of antibodies form immune complexes in type III hypersensitivity reactions?

    <p>IgG antibodies</p> Signup and view all the answers

    Where do immune complexes deposit in type III hypersensitivity reactions?

    <p>Small blood vessels</p> Signup and view all the answers

    What type of damage can immune complexes cause in type III hypersensitivity reactions?

    <p>Renal damage</p> Signup and view all the answers

    Which disease is an example of a type III hypersensitivity reaction?

    <p>Systemic lupus erythematosus</p> Signup and view all the answers

    What type of cells are involved in type IV hypersensitivity reactions?

    <p>T cells</p> Signup and view all the answers

    What type of immune reaction is hypersensitivity reaction?

    <p>Type B</p> Signup and view all the answers

    Which of the following is an example of a genetic variability causing oxidative crises?

    <p>G6PD deficiency</p> Signup and view all the answers

    What key immune components are involved in Type I hypersensitivity reactions?

    <p>Mast cells</p> Signup and view all the answers

    What is a common clinical feature associated with Type I hypersensitivity reactions?

    <p>Angioedema</p> Signup and view all the answers

    In Type II hypersensitivity reactions, what consequences depend entirely upon the tissue targeted and antibody binding?

    <p>Signs of anemia</p> Signup and view all the answers

    In organ transplant rejection, what plays a role similar to antibody-dependent cytotoxicity seen in Type II hypersensitivity reactions?

    <p>Complement activation</p> Signup and view all the answers

    Which type of hypersensitivity reaction is characterized by IgE-mediated mast cell activation?

    <p>Type I</p> Signup and view all the answers

    What is the key feature of type II hypersensitivity reactions?

    <p>IgG antibody-mediated destruction</p> Signup and view all the answers

    Which disease results from the immune destruction of insulin-producing cells?

    <p>Type I diabetes mellitus</p> Signup and view all the answers

    What is the primary outcome of immune damage to myelin sheaths around nerves in multiple sclerosis?

    <p>Focal neurological symptoms</p> Signup and view all the answers

    Which hypersensitivity reaction is characterized by immune complex-mediated tissue damage?

    <p>Type III</p> Signup and view all the answers

    In which type of hypersensitivity reaction is T-cell-mediated destruction of host cells a key mechanism?

    <p>Type IV</p> Signup and view all the answers

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