Immunology 2: Antibody vs Cell Mediated Immunity

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Questions and Answers

What is the primary aim of the Immunology 2 module?

To focus solely on laboratory techniques

To develop psychological understanding in dentistry

To apply biomedical principles to dental practice (correct)

To explore the basics of biology

Which statement correctly defines passive immunity?

It is a natural response to infectious diseases.

It only occurs artificially through vaccines.

It is acquired through the transfer of antibodies from one individual to another. (correct)

It is developed by an individual's immune system after exposure to an antigen.

What distinguishes antibody-mediated immunity from cell-mediated immunity?

Antibody-mediated immunity involves the production of antibodies, while cell-mediated immunity involves T cells. (correct)

Cell-mediated immunity uses antibodies to neutralize pathogens, while antibody-mediated immunity does not.

Antibody-mediated immunity relies on T cells, while cell-mediated immunity relies on B cells.

Both types of immunity involve the same mechanisms and cells.

Which of the following is an example of natural active immunity?

Contracting a disease and developing immunity Signup and view all the answers

What is an example of artificial passive immunity?

Treatment with monoclonal antibodies Signup and view all the answers

Which video is suggested for consolidating knowledge about the cellular immune response?

The Cellular Immune Response Signup and view all the answers

What method is primarily used for self-assessment in the Immunology 2 module?

Self-assessment quizzes Signup and view all the answers

What is a characteristic of antibodies produced in response to vaccination?

They are produced against a specific antigen. Signup and view all the answers

Which type of immunity is NOT classified as passive immunity?

Natural active immunity Signup and view all the answers

What is a common risk when immunity from a vaccine begins to run out?

The individual is at risk of infection. Signup and view all the answers

In the context of immunity, what does 'active' refer to?

Production of antibodies by the host Signup and view all the answers

How do antibodies function in the body's immune response?

They bind to specific surface structures on antigens. Signup and view all the answers

Which of these options best characterizes cell-mediated immunity?

Relies on T cells to identify and destroy infected cells Signup and view all the answers

What distinguishes artificial active immunity from natural immunity?

Artificial active immunity involves the administration of vaccines. Signup and view all the answers

Which scenario describes the transfer of antibodies from an immune person to a non-immune person?

Immunoglobulin transplant. Signup and view all the answers

What is the role of immunological memory in vaccinations?

It allows the body to respond faster to subsequent infections. Signup and view all the answers

What is a potential downside of relying on antibodies from breast milk?

They can lead to maternal antibodies overpowering infant immune response. Signup and view all the answers

What happens when a person is re-exposed to the same pathogen after initial vaccination?

A stronger and faster immune response occurs. Signup and view all the answers

Which of the following statements about snake antitoxin is correct?

It is a form of passive immunity. Signup and view all the answers

What occurs upon administration of a vaccine?

An immune reaction is induced against a weakened agent. Signup and view all the answers

Study Notes

Immunology 2 Module

Tutor: Ms P Lazarou
Module: Biomedical Sciences
Learning Outcomes (GDC 1.1): Develop dental therapy and dental hygiene principles from biomedical, behavioral, and materials sciences, to build knowledge from immunology studies.

Assessment

Formative: Quiz
Summative: Questions included in Biomedical Sciences assessment

Immunology 2 Content

Task 1: Study article "Antibody-mediated vs cell-mediate immunity" (pages 5-8).
Task 2: Complete self-assessment quiz on antibody-mediated and cell-mediated immunity.

Intended Learning Outcomes

Review antibody and cell-mediated immunity using resources and a self-assessment quiz.
Define and understand differences between antibody-mediated and cell-mediated immunity.
Understand passive and active immunizations.

Consolidation of Learning

Watch YouTube video "The Cellular Immune Response" (https://www.youtube.com/watch?v=oUpcRfpEh3c).
Watch YouTube video "ANTIGEN PROCESSING AND PRESENTATION" (https://www.youtube.com/watch?v=Bgd1qxQ0Dh4&feature=emb_logo).

Antibody-mediated and Cell-mediated Immunity Overview

Humoral Immunity: Antibody production by B lymphocytes targets extracellular microbes (e.g., bacteria). Antibodies mediate neutralization, lysis, and phagocytosis.
Cellular Immunity: T cells target intracellular microbes (e.g., viruses). Antigen-presenting cells process and present antigens to T cells. Helper T cells activate immune responses, cytotoxic T cells directly kill infected cells.

Passive and Active Immunity

Passive Immunity: Antibodies transferred (e.g., from mother's milk, artificial treatments like antitoxins). Short-lasting protection.
Natural Active Immunity: Antibodies develop within response to infection. Long-lasting immunity due to immunological memory.
Artificial Active Immunity: Antibodies developed as result of vaccines (immunization). A weakened or killed microorganism creates memory.

Immunisation

Artificial Active Immunity: Vaccines trigger antibody production after administration. Immunological memory develops from weakened/killed microorganism. Subsequent infections raise stronger, faster immune responses.

How Vaccines Work

A harmless version of a disease is introduced to train the body to make antibodies.
Later exposure to the disease will trigger immune responses.

References

Warrington, R. et al. (Article not specified, but noted as an introductory immunology and immunopathology).
McMahon & Sloan (2000): Essentials of Pathology for Dentistry.
Immunology.org (Allergy and autoimmune awareness resources provided).
JDRF (2018): Juvenile Diabetes Research Foundation report.
British Society for Immunology: Immunodeficiency resources.
Hindawi: Autoimmune Diseases and their Manifestations.

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Description

This quiz covers critical concepts from the Immunology 2 module, focusing on antibody-mediated and cell-mediated immunity. Students will define key differences and understand immunization processes while applying their knowledge through a series of self-assessment questions.