Immunogenetics: Structure of Lymphocyte Antigen Receptors

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What type of antigens can membrane-bound antibodies of B lymphocytes recognize?

Many types of chemical structures

What do the antigen receptors of B and T lymphocytes have in common?

Transmit biochemical signals that are fundamentally the same

What is unique about the function of T cell antigen receptors (TCRs) compared to antibodies (immunoglobulins)?

TCRs only function as membrane receptors

How do most T cell antigen receptors recognize antigens?

Only peptides bound to major histocompatibility complex (MHC) molecules

What is essential for signaling in lymphocytes, despite single antigens being shown in recognition?

Binding of two or more receptors to adjacent antigen molecules

What is a critical characteristic of membrane-bound antibodies serving as B lymphocyte antigen receptors?

Ability to recognize many types of chemical structures

What is the principal function of cellular receptors in the immune system?

Triggering responses of the cells

Why do antigen receptors of lymphocytes need to be able to bind to and distinguish between many different chemical structures?

To recognize a large variety of different antigens

Which type of receptors do B lymphocytes express to recognize antigens?

Membrane-bound antibodies

Why are antigen receptors considered clonally distributed in lymphocytes?

To ensure each clone is specific for a distinct antigen

What makes up the immune repertoire?

The total number of distinct lymphocyte clones

In adaptive immunity, what do effector T cells and antibodies recognize to perform their functions?

Antigens

Explore the structure of lymphocyte antigen receptors and the development of immune repertoires in the field of immunogenetics. Learn about the critical roles of antigen receptors in lymphocyte maturation and adaptive immune responses.

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