IgM
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IgM

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Questions and Answers

What is the main source of specific IgM production in humans and other studied mammals?

  • T cells in the bone marrow
  • Neutrophils in the blood
  • Macrophages in the lymph nodes
  • Plasmablasts in the spleen (correct)

    • Why is IgM also called an acute phase antibody?

  • It is the first antibody to appear in the response to initial exposure to an antigen (correct)
  • It is primarily found in chronic infections
  • It is only produced in response to secondary exposure to an antigen
  • It is the most abundant antibody in the body

    • What was the original term used for IgM due to its larger size?

  • α-microglobulin
  • δ-microglobulin
  • γ-macroglobulin (correct)
  • β-macroglobulin

    • What was the observed molecular weight of the antibody in horses hyper-immunized with pneumococcus polysaccharide?

    <p>990,000 daltons</p> Signup and view all the answers

    Why was detailed structural analysis of IgM impeded?

    <p>Due to the highly heterogeneous V domains of normal immunoglobulin</p> Signup and view all the answers

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