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Hypothalamus-Pituitary Axis

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30 Questions

What is the primary function of Corticotrophs in the pituitary gland?

Producing adrenocorticotropic hormone (ACTH)

Which hormone released by the hypothalamus stimulates the release of TSH and prolactin from the anterior pituitary?

Thyrotropin releasing hormone (TRH)

What is the effect of somatostatin on growth hormone secretion?

Inhibits GH secretion

Which of the following is NOT a target tissue for growth hormone?

Brain

What is the percentage of pituitary cells that produce prolactin?

10-15%

What is the function of thyrotrophs in the pituitary gland?

Stimulating the thyroid gland

Which hormone is released by the hypothalamus to stimulate the release of LH and FSH?

Gonadotropin releasing hormone (GnRH)

What is the effect of growth hormone on the body?

It increases the size of cells and stimulates mitosis

What is the percentage of pituitary cells that produce adrenocorticotropic hormone (ACTH)?

15-20%

What is the function of growth hormone releasing hormone (GHRH)?

Stimulates GH secretion

What is the primary mechanism by which growth hormone exerts its effects on growth?

Somatomedins (IGF)

What is the effect of growth hormone on protein metabolism?

Increased synthesis of proteins

What is the effect of growth hormone on fat metabolism?

Increased breakdown of fatty acids

What is the effect of growth hormone on carbohydrate metabolism?

Decreased uptake of glucose by cells

What is required for growth hormone to cause growth?

Both glucose and insulin

What is the typical rate of growth hormone secretion in children and adolescents?

6ng/ml

What is a stimulus for growth hormone secretion?

Hypoglycemia

What is the function of GHRH in growth hormone regulation?

Stimulation of growth hormone secretion

What is the effect of growth hormone on blood glucose levels?

Increased blood glucose levels

What is the term for the condition of excessive growth hormone secretion leading to excessive growth?

Gigantism

What is the height of Chandra Bahadur Dangi from Nepal?

21 and a half inches

What is the effect of increased levels of GH?

Diabetes mellitus

What is the chemical composition of oxytocin?

Nonapeptide

What is the action of oxytocin on the uterus?

It powerfully stimulates the gravid uterus toward end of gestation

What is the function of ADH in the body?

It conserves body water and regulates tonicity of body fluids

What is the effect of ADH on arterioles at higher concentration?

It constricts them

What stimulates the secretion of ADH?

Decrease in blood volume

What is the effect of hemorrhage on ADH secretion?

It stimulates ADH secretion

What is the effect of activities that increase blood pressure on ADH secretion?

They suppress ADH secretion

What is the relationship between ADH and blood pressure?

ADH regulates blood pressure

Learn about the hormones secreted by the hypothalamus and pituitary gland, including their chemistry, synthesis, functions, control, and common disorders. Understand the Hypothalamic-Pituitary Axis and its role in human physiology. Test your knowledge with this quiz!

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