Humoral Immunity
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Questions and Answers

Which type of host defense is mediated by secreted antibodies?

  • Humoral immunity (correct)
  • Innate immunity
  • Cellular immunity
  • Adaptive immunity

What is the function of antibodies in host defense?

  • To prevent infections by binding to and entering host cells
  • To reach microbes that live inside cells
  • To block microbes from binding to and entering host cells (correct)
  • To eliminate microbes, toxins, and infected cells from the body

What is the role of antibodies in defense against microbes that live inside cells?

  • To bind to these microbes after they enter host cells
  • To prevent spread of infection from infected to uninfected cells (correct)
  • To eliminate these microbes from the body
  • To bind to these microbes before they enter host cells

Which cells synthesize and secrete antibodies of different heavy-chain isotypes?

<p>Plasma cells (B)</p> Signup and view all the answers

What is the function of antibodies' Fab regions?

<p>To bind to and block the harmful effects of microbes and toxins (A)</p> Signup and view all the answers

What enhances the protective functions of antibodies?

<p>Isotype switching and affinity maturation (D)</p> Signup and view all the answers

What is the role of the neonatal Fc receptor (FcRn)?

<p>To protect IgG antibodies from intracellular catabolism (D)</p> Signup and view all the answers

Which receptor contributes to the long half-life of IgG molecules?

<p>FcRn (A)</p> Signup and view all the answers

Which type of antibody has a half-life of about 3 weeks?

<p>IgG (B)</p> Signup and view all the answers

What is the purpose of coupling proteins to an IgG Fc region?

<p>To increase their half-life (A)</p> Signup and view all the answers

What is the function of the tumor necrosis factor (TNF) receptor–Fc fusion protein?

<p>To act as an antagonist of TNF (A)</p> Signup and view all the answers

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