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Humoral Immunity

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Questions and Answers

Which type of host defense is mediated by secreted antibodies?

Humoral immunity (correct)

Innate immunity

Cellular immunity

Adaptive immunity

What is the function of antibodies in host defense?

To prevent infections by binding to and entering host cells

To reach microbes that live inside cells

To block microbes from binding to and entering host cells (correct)

To eliminate microbes, toxins, and infected cells from the body

What is the role of antibodies in defense against microbes that live inside cells?

To bind to these microbes after they enter host cells

To prevent spread of infection from infected to uninfected cells (correct)

To eliminate these microbes from the body

To bind to these microbes before they enter host cells

Which cells synthesize and secrete antibodies of different heavy-chain isotypes?

Plasma cells Signup and view all the answers

What is the function of antibodies' Fab regions?

To bind to and block the harmful effects of microbes and toxins Signup and view all the answers

What enhances the protective functions of antibodies?

Isotype switching and affinity maturation Signup and view all the answers

What is the role of the neonatal Fc receptor (FcRn)?

To protect IgG antibodies from intracellular catabolism Signup and view all the answers

Which receptor contributes to the long half-life of IgG molecules?

FcRn Signup and view all the answers

Which type of antibody has a half-life of about 3 weeks?

IgG Signup and view all the answers

What is the purpose of coupling proteins to an IgG Fc region?

To increase their half-life Signup and view all the answers

What is the function of the tumor necrosis factor (TNF) receptor–Fc fusion protein?

To act as an antagonist of TNF Signup and view all the answers