5 Types of Antibodies and Their Functions

What type of antibody is responsible for the primary response to an antigen?

Which antibody is most commonly found and protects portals of entry?

Which antibody responds in allergic reactions and parasite infections?

Which antibody is effective against antigens in the secondary response?

Types of Antibodies and Their Functions

IgM
- First antibodies produced in response to an initial antigen exposure.
- Primarily located on B cells, playing a crucial role in the early immune response.
IgA
- Most abundant antibody in mucosal areas, providing protection at common entry points.
- Present in bodily secretions such as saliva, tears, breast milk, and mucus, as well as in blood plasma.
IgE
- Associated with allergic reactions and immune responses to parasites.
- Exists in blood plasma and binds to allergens and parasites, triggering histamine release from mast cells.
IgD
- Found primarily on the surface of mature B cells, functioning mainly as a receptor for antigens.
- Its exact role in the immune response is less understood but is linked to the activation of B cells.
IgG
- Most prevalent antibody in the secondary immune response, providing long-term immunity.
- Highly effective against a wide range of pathogens, including toxins, viruses, and bacteria, circulating freely in blood plasma.

Explore the five main types of antibodies and their unique functions with this flashcard quiz. Learn about IgM, IgA, IgE, IgD, and IgG as you test your knowledge on their responses to antigens and infections. Perfect for students of immunology and those delving into the human immune system.