Antibodies

IgG = made when we know animal has been exposed for a long period of time or for a second time IgM = made during the first exposure (first time animal gets the vx or disease) IgA = can leave blood and enter tissue fluid IgE = associated with allergic response

Accounts for 80% of all antibodies, responsible for resistance against many viruses, bacteria, and bacterial toxins = IgG Attaches as an individual molecule to the exposed surfaces of basophils and mast cells = IgE Is an individual molecule on the surfaces of B cells, where it can bind antigens in the extracellular fluid. (this binding can play a role in the sensitization of the B cell involved) = IgD The first class of antibody secreted after an antigen is encountered. = IgM

Found primarily in glandular secretions such as mucus, tears, saliva, and semen. These antibodies attack pathogens before they gain access to internal tissues = IgA The anti-A and anti-B antibodies responsible for agglutination of incomplete blood types = IgM Is an individual molecule on the surfaces of B cells, where it can bind antigens in the extracellular fluid. (this binding can play a role in the sensitization of the B cell involved) = IgD Attaches as an individual molecule to the exposed surfaces of basophils and mast cells = IgE