HSV Infection Diagnosis Methods

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main characteristic feature of genital warts?

  • Presence of immature squamous cells with a perinuclear zone
  • Presence of goblet cells with a clear perinuclear zone
  • Presence of mature squamous cells with a clear perinuclear zone (correct)
  • Presence of basal cells with a clear cytoplasm

Which technique was initially used for HPV detection but was labor-intensive and time-consuming?

  • Hybrid capture HPV DNA Test (hc2)
  • Dot blot hybridization
  • Polymerase chain reaction
  • Southern blot hybridization (correct)

Which HPV detection technique can differentiate between 'low-risk' and 'high-risk' genotypes?

  • Dot blot hybridization
  • Polymerase chain reaction
  • Hybrid capture HPV DNA Test (hc2) (correct)
  • Pap smear

Which test can detect as little as 1 pg of HPV/ml?

<p>Hybrid capture HPV DNA Test (hc2) (C)</p> Signup and view all the answers

Which technique selectively amplifies the HPV sequences present in biological specimens?

<p>Polymerase chain reaction (A)</p> Signup and view all the answers

How is the Pap smear specimen collected for detection of viral infections like HPV and Herpes?

<p>Vesicle swab collection (D)</p> Signup and view all the answers

Which technique is the most sensitive for detecting HSV DNA?

<p>Polymerase chain reaction (PCR) (A)</p> Signup and view all the answers

What is the primary method for differentiating between HSV-1 and HSV-2?

<p>Serologic assays based on glycoprotein G antigens (B)</p> Signup and view all the answers

Which of the following is true about the treatment of Herpes simplex?

<p>Acyclovir prevents chain elongation by inhibiting viral DNA polymerase (C)</p> Signup and view all the answers

Which test can detect the presence of IgM or rising IgG titres for primary HSV infection?

<p>Complement fixation test (C)</p> Signup and view all the answers

What is the diagnostic significance of giant cells or cow dry type A intranuclear inclusion bodies in a stained smear?

<p>Diagnostic for Herpes simplex virus infection (D)</p> Signup and view all the answers

Which method is used to collect samples from vesicles for laboratory diagnosis of HSV?

<p>Culture using swab from lesion base (D)</p> Signup and view all the answers

Which laboratory technique is commonly used to detect viral RNA in clinical specimens for HIV diagnosis?

<p>Amplification assays (D)</p> Signup and view all the answers

What is the most widely used confirmation assay for HIV diagnosis that involves detecting antibodies to specific viral proteins?

<p>Western blot technique (D)</p> Signup and view all the answers

Which viral proteins are most commonly assessed in the Western blot technique for HIV diagnosis?

<p>p24 and envelope glycoproteins (D)</p> Signup and view all the answers

What does a decline in CD4+ cell count to less than 200 cells/μL correspond to in HIV/AIDS progression?

<p>Increased risk of opportunistic infections (D)</p> Signup and view all the answers

Which technique is used to evaluate CD4+ T helper subset count for AIDS diagnosis?

<p>Immunofluorescence with monoclonal anti-CD4 antibodies (A)</p> Signup and view all the answers

Which statement about the importance of viral load in HIV progression is accurate?

<p>Lower viral load predicts disease progression (A)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Laboratory Diagnosis of HSV Infections
19 questions
Use Quizgecko on...
Browser
Browser