HSV Infection Diagnosis Methods

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What is the main characteristic feature of genital warts?

Presence of immature squamous cells with a perinuclear zone

Presence of goblet cells with a clear perinuclear zone

Presence of mature squamous cells with a clear perinuclear zone (correct)

Presence of basal cells with a clear cytoplasm

Which technique was initially used for HPV detection but was labor-intensive and time-consuming?

Hybrid capture HPV DNA Test (hc2)

Dot blot hybridization

Polymerase chain reaction

Southern blot hybridization (correct)

Which HPV detection technique can differentiate between 'low-risk' and 'high-risk' genotypes?

Dot blot hybridization

Polymerase chain reaction

Hybrid capture HPV DNA Test (hc2) (correct)

Pap smear

Which test can detect as little as 1 pg of HPV/ml?

Hybrid capture HPV DNA Test (hc2) Signup and view all the answers

Which technique selectively amplifies the HPV sequences present in biological specimens?

Polymerase chain reaction Signup and view all the answers

How is the Pap smear specimen collected for detection of viral infections like HPV and Herpes?

Vesicle swab collection Signup and view all the answers

Which technique is the most sensitive for detecting HSV DNA?

Polymerase chain reaction (PCR) Signup and view all the answers

What is the primary method for differentiating between HSV-1 and HSV-2?

Serologic assays based on glycoprotein G antigens Signup and view all the answers

Which of the following is true about the treatment of Herpes simplex?

Acyclovir prevents chain elongation by inhibiting viral DNA polymerase Signup and view all the answers

Which test can detect the presence of IgM or rising IgG titres for primary HSV infection?

Complement fixation test Signup and view all the answers

What is the diagnostic significance of giant cells or cow dry type A intranuclear inclusion bodies in a stained smear?

Diagnostic for Herpes simplex virus infection Signup and view all the answers

Which method is used to collect samples from vesicles for laboratory diagnosis of HSV?

Culture using swab from lesion base Signup and view all the answers

Which laboratory technique is commonly used to detect viral RNA in clinical specimens for HIV diagnosis?

Amplification assays Signup and view all the answers

What is the most widely used confirmation assay for HIV diagnosis that involves detecting antibodies to specific viral proteins?

Western blot technique Signup and view all the answers

Which viral proteins are most commonly assessed in the Western blot technique for HIV diagnosis?

p24 and envelope glycoproteins Signup and view all the answers

What does a decline in CD4+ cell count to less than 200 cells/μL correspond to in HIV/AIDS progression?

Increased risk of opportunistic infections Signup and view all the answers

Which technique is used to evaluate CD4+ T helper subset count for AIDS diagnosis?

Immunofluorescence with monoclonal anti-CD4 antibodies Signup and view all the answers

Which statement about the importance of viral load in HIV progression is accurate?

Lower viral load predicts disease progression Signup and view all the answers

HSV Infection Diagnosis Methods

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Questions and Answers

What is the main characteristic feature of genital warts?

Which technique was initially used for HPV detection but was labor-intensive and time-consuming?

Which HPV detection technique can differentiate between 'low-risk' and 'high-risk' genotypes?

Which test can detect as little as 1 pg of HPV/ml?

Which technique selectively amplifies the HPV sequences present in biological specimens?

How is the Pap smear specimen collected for detection of viral infections like HPV and Herpes?

Which technique is the most sensitive for detecting HSV DNA?

What is the primary method for differentiating between HSV-1 and HSV-2?

Which of the following is true about the treatment of Herpes simplex?

Which test can detect the presence of IgM or rising IgG titres for primary HSV infection?

What is the diagnostic significance of giant cells or cow dry type A intranuclear inclusion bodies in a stained smear?

Which method is used to collect samples from vesicles for laboratory diagnosis of HSV?

Which laboratory technique is commonly used to detect viral RNA in clinical specimens for HIV diagnosis?

What is the most widely used confirmation assay for HIV diagnosis that involves detecting antibodies to specific viral proteins?

Which viral proteins are most commonly assessed in the Western blot technique for HIV diagnosis?

What does a decline in CD4+ cell count to less than 200 cells/μL correspond to in HIV/AIDS progression?

Which technique is used to evaluate CD4+ T helper subset count for AIDS diagnosis?

Which statement about the importance of viral load in HIV progression is accurate?

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