6 Questions
What challenges have prompted innovative approaches in the use of rebamipide for dry eye treatment?
Low bioavailability and vision clouding post-installation
What is the range of concentrations evaluated in the study for rebamipide?
4-24 µg/ml
What is the purpose of encapsulating rebamipide in ethosomes?
To enhance ocular bioavailability
What was the entrapment efficiency of rebamipide in ethosomes?
76% ± 7
What was the drug content percentage found in the prepared ethosomes?
93% ± 6
What kind of kinetics was demonstrated by the drug release process?
Zero-order kinetics
Explore the development of a High-Performance Liquid Chromatography (HPLC) method for quantifying rebamipide encapsulated in ethosomes, a lipid-based nanovesicle. Learn about the potential of rebamipide as a therapeutic agent for dry eye and the benefits of encapsulation to enhance ocular bioavailability.
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