Hematology Abnormalities Quiz

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Questions and Answers

What does an increased mean corpuscular volume (MCV) indicate in blood cells?

  • Decreased size of red blood cells
  • No impact on red blood cell size
  • Increased size of red blood cells (correct)
  • Normal size of red blood cells

What is the typical range of normal adult hemoglobin (HbA) in the body?

  • 80%-85%
  • 90%-95%
  • 95%-98% (correct)
  • 60%-70%

What is the likely red cell condition when the hematocrit (HCT) reflects a decrease due to enlarged red cell size?

  • Anisocytosis (correct)
  • Leukopenia
  • Neutropenia
  • Thalassemia

Which characteristic is NOT typically found on a peripheral blood smear in the condition described?

<p>Presence of small platelets (A)</p> Signup and view all the answers

Which component is typically increased in 90% of cases with the condition described?

<p>Mean corpuscular hemoglobin (MCH) (B)</p> Signup and view all the answers

What is the major difference between quantitative and qualitative defects in hemoglobinopathy?

<p>Quantitative defects result in reduced hemoglobin levels, while qualitative defects affect the hemoglobin structure. (C)</p> Signup and view all the answers

What is the primary cause of Hemoglobinopathy?

<p>Inherited or genetic defect related to hemoglobin (C)</p> Signup and view all the answers

What is the normal percentage of HbA (azẞ2) in normal adult hemoglobin?

<p>95%-98% (A)</p> Signup and view all the answers

Which type of Hemoglobinopathy results in a structural abnormality of the hemoglobin molecule?

<p>Qualitative defect (C)</p> Signup and view all the answers

What is the condition of a person who has only one affected gene in Hemoglobinopathy?

<p>Trait condition (A)</p> Signup and view all the answers

Which of the following is NOT a syndrome associated with Hemoglobinopathy?

<p>Leukemia (C)</p> Signup and view all the answers

What is the primary characteristic of Beta Thalassemia Minor?

<p>Only one allele is affected (B)</p> Signup and view all the answers

What is the typical percentage of HbA₂ (α262) in normal adult hemoglobin?

<p>2-3% (D)</p> Signup and view all the answers

Which type of Hemoglobinopathy results in a deficiency in the synthesis of normal adult hemoglobin?

<p>Quantitative defect (C)</p> Signup and view all the answers

Flashcards

Increased MCV indicates?

Increased size of red blood cells.

Normal adult HbA range?

95%-98%

HCT decrease due to enlarged cells indicates?

Anisocytosis

What is NOT on blood smear?

Presence of small platelets

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Increased component in 90% of cases?

Mean corpuscular hemoglobin (MCH)

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Quantitative vs. qualitative defects?

Quantitative defects reduce hemoglobin levels; qualitative defects affect hemoglobin structure.

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Primary cause of Hemoglobinopathy?

Inherited or genetic defect related to hemoglobin.

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Normal percentage of HbA?

95%-98%

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Structural abnormality of hemoglobin?

Qualitative defect

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One affected gene means?

Trait condition

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NOT a syndrome associated with Hemoglobinopathy?

Leukemia

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Primary characteristic of Beta Thalassemia Minor?

Only one allele is affected

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Typical percentage of HbAâ‚‚?

2-3%

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Deficiency in the synthesis of normal adult hemoglobin?

Quantitative defect

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