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White Blood Cell Abnormalities Quiz

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Questions and Answers

What is the mechanism of leukocytosis?

Increased movement of immature cells from the bone marrow proliferative compartment (correct)

Increased movement from marginating pool to circulating pool

Increased movement from circulation to the tissues

Decreased movement from marginating pool to circulating pool

What is the normal range for absolute neutrophil count (ANC) in the blood?

2 to 7.7 x 109/L (correct)

0.5 to 2.7 x 109/L

8 to 12 x 109/L

13 to 18 x 109/L

What does neutrophilic left shift refer to?

Increase in the number of immature cells in the myelocytic cell line (correct)

Absence of neutrophils in the bone marrow

Decrease in the number of neutrophils in the bone marrow

Presence of mature neutrophils in the bloodstream

What defines neutrophilia in adults?

<p>Absolute increase in neutrophils > 7.0 x 109/L</p> Signup and view all the answers

Which mechanism of neutrophilia involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool?

<p>Transfer of neutrophils from the bone marrow storage pool to the circulating pool</p> Signup and view all the answers

Study Notes

Leukocytosis Mechanism

Leukocytosis is a reactive process in which the body responds to inflammation, infection, or tissue damage by increasing the production of white blood cells, particularly neutrophils.

Absolute Neutrophil Count (ANC)

The normal range for ANC in the blood is 1.5-7.0 x 10^9/L.

Neutrophilic Left Shift

Neutrophilic left shift refers to the presence of immature neutrophils (band cells) in the peripheral blood, indicating a response to an infection or inflammation.

Neutrophilia

Neutrophilia is defined as an ANC above 7.0 x 10^9/L in adults.
Neutrophilia can occur through two mechanisms: demargination, which involves the release of neutrophils from the marginated pool, and mobilization, which involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.

Mechanisms of Neutrophilia

Mobilization is the mechanism of neutrophilia that involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.

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Description

Test your knowledge on quantitative abnormalities of white blood cells, which are not caused by clonal or neoplastic changes in hematopoietic precursor cells. Explore the causes, genetic and acquired, that affect different lineages of white blood cells and their circulation.