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Questions and Answers
What is the mechanism of leukocytosis?
What is the normal range for absolute neutrophil count (ANC) in the blood?
What does neutrophilic left shift refer to?
What defines neutrophilia in adults?
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Which mechanism of neutrophilia involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool?
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Study Notes
Leukocytosis Mechanism
- Leukocytosis is a reactive process in which the body responds to inflammation, infection, or tissue damage by increasing the production of white blood cells, particularly neutrophils.
Absolute Neutrophil Count (ANC)
- The normal range for ANC in the blood is 1.5-7.0 x 10^9/L.
Neutrophilic Left Shift
- Neutrophilic left shift refers to the presence of immature neutrophils (band cells) in the peripheral blood, indicating a response to an infection or inflammation.
Neutrophilia
- Neutrophilia is defined as an ANC above 7.0 x 10^9/L in adults.
- Neutrophilia can occur through two mechanisms: demargination, which involves the release of neutrophils from the marginated pool, and mobilization, which involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.
Mechanisms of Neutrophilia
- Mobilization is the mechanism of neutrophilia that involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.
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Description
Test your knowledge on quantitative abnormalities of white blood cells, which are not caused by clonal or neoplastic changes in hematopoietic precursor cells. Explore the causes, genetic and acquired, that affect different lineages of white blood cells and their circulation.
