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Questions and Answers
What is the mechanism of leukocytosis?
What is the mechanism of leukocytosis?
- Increased movement of immature cells from the bone marrow proliferative compartment (correct)
- Increased movement from marginating pool to circulating pool
- Increased movement from circulation to the tissues
- Decreased movement from marginating pool to circulating pool
What is the normal range for absolute neutrophil count (ANC) in the blood?
What is the normal range for absolute neutrophil count (ANC) in the blood?
- 2 to 7.7 x 109/L (correct)
- 0.5 to 2.7 x 109/L
- 8 to 12 x 109/L
- 13 to 18 x 109/L
What does neutrophilic left shift refer to?
What does neutrophilic left shift refer to?
- Increase in the number of immature cells in the myelocytic cell line (correct)
- Absence of neutrophils in the bone marrow
- Decrease in the number of neutrophils in the bone marrow
- Presence of mature neutrophils in the bloodstream
What defines neutrophilia in adults?
What defines neutrophilia in adults?
Which mechanism of neutrophilia involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool?
Which mechanism of neutrophilia involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool?
Flashcards
Leukocytosis mechanism
Leukocytosis mechanism
Increased movement of immature cells from the bone marrow.
Normal ANC range
Normal ANC range
2 to 7.7 x 10^9/L.
Neutrophilic left shift
Neutrophilic left shift
More immature cells (myelocytes) are in the blood.
Neutrophilia in adults
Neutrophilia in adults
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Neutrophil movement in neutrophilia
Neutrophil movement in neutrophilia
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Study Notes
Leukocytosis Mechanism
- Leukocytosis is a reactive process in which the body responds to inflammation, infection, or tissue damage by increasing the production of white blood cells, particularly neutrophils.
Absolute Neutrophil Count (ANC)
- The normal range for ANC in the blood is 1.5-7.0 x 10^9/L.
Neutrophilic Left Shift
- Neutrophilic left shift refers to the presence of immature neutrophils (band cells) in the peripheral blood, indicating a response to an infection or inflammation.
Neutrophilia
- Neutrophilia is defined as an ANC above 7.0 x 10^9/L in adults.
- Neutrophilia can occur through two mechanisms: demargination, which involves the release of neutrophils from the marginated pool, and mobilization, which involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.
Mechanisms of Neutrophilia
- Mobilization is the mechanism of neutrophilia that involves the transfer of neutrophils from the bone marrow storage pool to the circulating pool.
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