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Haemolytic Uraemic Syndrome (HUS) Quiz

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Questions and Answers

What is the classic triad associated with Haemolytic uraemic syndrome (HUS)?

Microangiopathic haemolytic anaemia, Acute kidney injury, Thrombocytopenia (low platelets)

What triggers thrombosis in small blood vessels in HUS?

Shiga toxins from either E. coli O157 or Shigella

What is the most common age group affected by HUS?

Children

How does HUS lead to thrombocytopenia (low platelets)?

The formation of blood clots consumes platelets, leading to thrombocytopenia. Signup and view all the answers

What is Microangiopathic haemolytic anaemia (MAHA) and how does it occur in HUS?

It involves the destruction of red blood cells due to pathology in the small vessels (microangiopathy). Tiny blood clots partially obstruct the small blood vessels and churn the red blood cells as they pass through, causing them to rupture. Signup and view all the answers

What is the first symptom of gastroenteritis caused by E. coli O157 and Shigella?

Diarrhoea Signup and view all the answers

What treatment for gastroenteritis caused by E. coli O157 or Shigella increases the risk of HUS?

Antibiotics and anti-motility medication (e.g., loperamide) Signup and view all the answers

What effect does thrombosis in small blood vessels have on the kidney in HUS?

The blood flow through the kidney is affected by thrombi and damaged red blood cells, leading to acute kidney injury. Signup and view all the answers

What is the main trigger for HUS?

Shiga toxins from either E. coli O157 or Shigella Signup and view all the answers

What are the two bacteria that cause gastroenteritis and can lead to HUS?

E. coli O157 and Shigella Signup and view all the answers