HACEK Bacteria and Neisseria Species
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Questions and Answers

Which characteristic is true for Eikenella corrodens?

  • It ferments carbohydrates.
  • It is encapsulated.
  • It has an ammonia odor. (correct)
  • It is a large bacillus.
  • What is the primary cause of meningitis in adults?

  • Eikenella corrodens
  • Neisseria gonnorhoeae
  • Neisseria meningitidis (correct)
  • Moraxella species
  • Which feature distinguishes Neisseria gonorrhoeae from Neisseria meningitidis?

  • Presence of capsulation
  • Association with pneumonia
  • Presence of pili (correct)
  • Ability to ferment maltose
  • In which locations are Neisseria meningitidis infections likely to occur in epidemic waves?

    <p>College dorms and military camps</p> Signup and view all the answers

    What is an effective treatment for Neisseria gonorrhoeae infections?

    <p>Cefixime</p> Signup and view all the answers

    Which of the following is a consequence of untreated gonococcal ophthalmia neonatorum?

    <p>Blindness</p> Signup and view all the answers

    What do OPA proteins in Neisseria gonorrhoeae assist with?

    <p>Adhesion of gonococci</p> Signup and view all the answers

    Which chemical property is true for Neisseria meningitidis?

    <p>It can ferment maltose.</p> Signup and view all the answers

    Which factor is considered a risk for Mannan infections caused by Neisseria meningitidis?

    <p>High population density</p> Signup and view all the answers

    What type of bacteria is Eikenella corrodens?

    <p>Fastidious gram-negative rod</p> Signup and view all the answers

    Which feature differentiates Neisseria gonorrhoeae from Neisseria meningitidis?

    <p>Existence of pili</p> Signup and view all the answers

    What is a significant clinical consequence of untreated gonococcal ophthalmia neonatorum?

    <p>Blindness</p> Signup and view all the answers

    Which treatment is currently recommended for Neisseria gonorrhoeae infections?

    <p>Cefixime and ceftriaxone</p> Signup and view all the answers

    What is the natural host for Neisseria meningitidis?

    <p>Humans</p> Signup and view all the answers

    Which clinical condition is primarily associated with Moraxella species?

    <p>Pneumonia</p> Signup and view all the answers

    What is the main mechanism by which Neisseria meningitidis can cause toxic effects in disease?

    <p>Lipopolysaccharides</p> Signup and view all the answers

    Which group of individuals is particularly vulnerable to Neisseria meningitidis infections during epidemic waves?

    <p>College students</p> Signup and view all the answers

    Which characteristic is true for Eikenella corrodens regarding its metabolism?

    <p>Is oxidase positive</p> Signup and view all the answers

    What key characteristic does Eikenella corrodens exhibit?

    <p>Oxidase positive and cannot ferment carbohydrates</p> Signup and view all the answers

    Which of the following is most commonly associated with Neisseria gonorrhoeae infections?

    <p>Genitourinary tract</p> Signup and view all the answers

    Identify a treatment option for Neisseria gonorrhoeae infections that is currently recommended.

    <p>Ciprofloxacin</p> Signup and view all the answers

    What is the primary role of pili in Neisseria gonorrhoeae?

    <p>Aid in adhesion to host cells</p> Signup and view all the answers

    What is a common characteristic of Neisseria meningitidis?

    <p>Ferments maltose and is capsulated</p> Signup and view all the answers

    What specific structure on Neisseria gonorrhoeae aids in its attachment to human cells?

    <p>Pili</p> Signup and view all the answers

    In which context is Neisseria meningitidis likely to occur in epidemic waves?

    <p>College dorms and military camps</p> Signup and view all the answers

    Which clinical outcome is associated with untreated gonococcal ophthalmia neonatorum?

    <p>Blindness</p> Signup and view all the answers

    How does Neisseria meningitidis typically enter the body?

    <p>Via the respiratory tract</p> Signup and view all the answers

    What is the primary mode of transmission for Neisseria gonorrhoeae in adults?

    <p>Sexual contact</p> Signup and view all the answers

    Which feature helps differentiate Neisseria meningitidis from other bacteria?

    <p>Capsule formation</p> Signup and view all the answers

    What type of bacterium is Neisseria gonorrhoeae classified as?

    <p>Gram-negative cocci</p> Signup and view all the answers

    What is the role of OPA proteins in Neisseria gonorrhoeae?

    <p>Adhesion of gonococci to host cells</p> Signup and view all the answers

    Which of the following statements about Eikenella corrodens is true?

    <p>It is oxidase positive and does not ferment carbohydrates.</p> Signup and view all the answers

    What is a likely consequence of untreated infections by Neisseria gonorrhoeae in adults?

    <p>Septic arthritis</p> Signup and view all the answers

    What do the capsulated structures of Neisseria meningitidis contribute to?

    <p>Increased virulence</p> Signup and view all the answers

    What is the primary treatment for infections caused by Neisseria gonorrhoeae now that penicillin is ineffective?

    <p>Cefixime or Ceftriaxone</p> Signup and view all the answers

    Which of the following is associated with Moraxella species?

    <p>Bronchitis and pneumonia</p> Signup and view all the answers

    Study Notes

    HACEK Bacteria

    • Eikenella corrodens is a small, fastidious, gram-negative rod found in the gingival and bowel flora.
    • Eikenella corrodens is oxidase positive, does not ferment carbohydrates, and produces an ammonia odor.
    • Eikenella corrodens can be isolated from wounds caused by human bites.

    Moraxella Species

    • Moraxella species are coccobacilli associated with bronchitis and pneumonia.

    Neisseria Species

    • Neisseria gonorrhoeae and Neisseria meningitidis are two significant species of Neisseria.

    Neisseria Meningitidis

    • Neisseria meningitidis is a capsulated bacteria that is a normal part of the upper respiratory flora.
    • Neisseria meningitidis ferments maltose and is a leading cause of meningitis in adults.
    • There are 13 serogroups of Neisseria meningitidis and vaccines are available to protect against them.
    • Humans are the natural host for Neisseria meningitidis, which enters the body through the nasopharynx.
    • Neisseria meningitidis lipopolysaccharides can cause toxic effects during infection, potentially leading to coma.

    Neisseria Gonorrhoeae

    • Neisseria gonorrhoeae is the cause of the sexually transmitted disease Gonorrhea.
    • Neisseria gonorrhoeae lacks a capsule and does not ferment maltose.
    • Neisseria gonorrhoeae has pili (hair-like structures) that aid in adhesion.
    • OPA proteins in Neisseria gonorrhoeae are involved in attaching to host cells.
    • Neisseria gonorrhoeae can infect the genitourinary tract, eyes, and rectum.
    • In men, gonorrhea often presents with a creamy, yellow pus discharge.
    • In women, the infection can extend from the endocervix to the vagina.
    • Neisseria gonorrhoeae can lead to septic arthritis.
    • Penicillin is no longer an effective treatment for gonorrhea, with cefixime and ceftriaxone being the current options.

    Epidemics

    • Gonorrhea can occur in epidemic waves, often seen in places like college dorms and military camps.
    • While penicillin is used to treat gonorrhea, it may not entirely eliminate the infection. Rifampin or ciprofloxacin are often prescribed alongside penicillin.

    Gonococcal Ophthalmia Neonatorum

    • Gonococcal ophthalmia neonatorum is an eye infection in newborns acquired during birth through the infected birth canal.
    • Left untreated, gonococcal ophthalmia neonatorum can lead to blindness.

    HACEK Bacteria

    • Eikenella corrodens: a small, fastidious, gram-negative rod found in the gingival and bowel flora.
    • Eikenella corrodens: known for being oxidase positive, does not ferment carbohydrates, and produces an ammonia odor. It is commonly isolated from wounds caused by human bites.

    Moraxella species

    • Coccobacillus typically associated with bronchitis and pneumonia.

    Neisseria species

    • N. gonorrhoeae and N. meningitidis are the two notable species.

    Neisseria Meningitidis

    • A capsulated bacterium that resides in the upper respiratory tract.
    • It is known to ferment maltose.
    • It is a leading cause of meningitis in adults.
    • It has 13 serogroups, with vaccines available for protection.
    • Humans are the natural host, entering through the nasopharynx.
    • The meningococcal lipopolysaccharides are responsible for causing toxic effects during infection.
    • The infection may progress to coma.

    Neisseria Gonorrhoeae

    • The causative agent of the sexually transmitted disease, gonorrhea.
    • It is a non-capsulated bacterium that cannot ferment maltose.
    • It has pili (hair-like structures) that play a role in adhesion.
    • It attacks the genitourinary tract, eyes, and rectum.
    • Men usually have creamy, yellow pus discharge.
    • Females typically experience endocervical infection extending to the vagina.
    • The bacteria can lead to septic arthritis.
    • Penicillin is no longer an option for treatment. Cefixime and ceftriaxone are the preferred medications.

    Epidemic Waves in Meningococcemia

    • Occur in crowded environments like college dorms and military camps.
    • Treatment with penicillin is effective, but often requires additional medications like rifampin or ciprofloxacin to eliminate the bacteria.

    Gonococcal Ophthalmia Neonatorum

    • A serious eye infection in newborns acquired during birth canal infection.
    • Untreated gonococcal ophthalmia neonatorum can lead to blindness.

    HACEK Bacteria

    • Eikenella corrodens is a small, fastidious, gram-negative rod found in the gingival and bowel flora.
    • Eikenella corrodens is oxidase-positive and does not ferment carbohydrates.
    • Eikenella corrodens is known for its ammonia-like odor and is commonly isolated from wounds caused by human bites.

    Moraxella Species

    • Moraxella species are coccobacilli commonly associated with bronchitis and pneumonia.

    Neisseria Species

    • Neisseria gonorrhoeae and Neisseria meningitidis are both significant pathogenic bacteria within the Neisseria genus.

    Neisseria Meningitidis

    • Neisseria meningitidis is a capsulated bacterium part of the normal upper respiratory flora.
    • Neisseria meningitidis ferments maltose and is a leading cause of meningitis in adults.
    • Neisseria meningitidis has 13 serogroups, and vaccines are available to protect against them.
    • Neisseria meningitidis is transmitted through the nasopharynx.
    • Neisseria meningitidis's lipopolysaccharides are responsible for the organism's toxic effects in disease.
    • Neisseria meningitidis infections can lead to coma.

    Neisseria Gonorrhoeae

    • Neisseria gonorrhoeae causes gonorrhea, a sexually transmitted disease.
    • Neisseria gonorrhoeae lacks a capsule and does not ferment maltose.
    • Neisseria gonorrhoeae has pili, hair-like structures, and OPA proteins, which contribute to adhesion.
    • Neisseria gonorrhoeae can infect the genitourinary tract, eyes, and rectum.
    • Neisseria gonorrhoeae infections in men are usually characterized by creamy, yellow pus.
    • Neisseria gonorrhoeae infections in women can spread to the endocervix and extend to the vagina.
    • Neisseria gonorrhoeae infections can lead to septic arthritis.
    • Penicillin is no longer an effective treatment for Neisseria gonorrhoeae. Recommended treatments are cefixime and ceftriaxone.

    Gonococcal Ophthalmia Neonatorum

    • Gonococcal ophthalmia neonatorum is an infection in newborns acquired during passage through the birth canal.
    • Untreated gonococcal ophthalmia neonatorum can cause blindness.

    HACEK Bacteria

    • Eikenella corrodens: small fastidious gram-negative rod, part of gingival and bowel flora, oxidase positive, does not ferment carbohydrates, emits ammonia odor, can be isolated from wounds due to human bites

    Moraxella Species

    • Coccobacillus, associated with bronchitis and pneumonia

    Neisseria Species

    • N. gonorrhoeae: causes gonorrhea
    • N. Meningitidis: causes meningitis

    Neisseria Meningitidis

    • Capsulated, part of upper normal respiratory flora, ferments maltose, leading cause of meningitis in adults, 13 serogroups
    • Humans are the natural host, nasopharynx is the portal of entry
    • Meningococcal lipopolysaccharides are responsible for toxic effects in the disease
    • Can progress to coma

    Neisseria Gonnorhoeae

    • Causes gonorrhea, no capsule, cannot ferment maltose, has pili, responsible for adhesion to gonococci
    • Attacks the genitourinary tract, eyes, and rectum
    • Men usually have creamy, yellow pus
    • Females have endocervix, extending to the vagina
    • Can lead to septic arthritis
    • Penicillin is no longer used; Cefixime and Ceftriaxone are the preferred options

    Epidemics of Neisseria gonnorhoeae

    • Occur in waves: college dorms and military camps
    • Treatment is penicillin but needs to be followed up by rifampin or ciprofloxacin to eliminate the drug

    Gonococcal Ophthalmia Neonatorum

    • Acquired during infection of the birth canal
    • Left untreated can lead to blindness

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    Description

    This quiz covers key aspects of HACEK bacteria, particularly Eikenella corrodens, as well as Neisseria species including Neisseria gonorrhoeae and Neisseria meningitidis. Learn about their characteristics, associations with diseases, and clinical significance.

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