HACEK and Neisseria Bacteria Overview
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Questions and Answers

Which of the following statements about Neisseria meningitidis is correct?

  • It is part of the upper normal respiratory flora. (correct)
  • It is a non-capsulated bacterium.
  • It primarily causes urinary tract infections.
  • It does not ferment any carbohydrates.
  • What is the primary cause of endocervical infections in females?

  • Neisseria gonorrhoeae (correct)
  • Neisseria meningitidis
  • Eikenella corrodens
  • Moraxella species
  • Which treatment option is currently recommended for Neisseria gonorrhoeae infections?

  • Tetracycline
  • Amoxicillin
  • Trimethoprim-sulfamethoxazole
  • Cefixime and ceftriaxone (correct)
  • What is a characteristic feature of Eikenella corrodens?

    <p>It is oxidase positive.</p> Signup and view all the answers

    Which of the following complications can arise from an untreated gonococcal ophthalmia neonatorum?

    <p>Blindness</p> Signup and view all the answers

    What is a characteristic of Neisseria gonorrhoeae that differentiates it from Neisseria meningitidis?

    <p>Presence of pili</p> Signup and view all the answers

    Which of the following statements about Eikenella corrodens is incorrect?

    <p>It can ferment carbohydrates.</p> Signup and view all the answers

    In which scenario is Neisseria meningitidis most likely to occur in an epidemic?

    <p>In college dormitories</p> Signup and view all the answers

    What is the primary outcome of untreated gonococcal ophthalmia neonatorum?

    <p>Potential for blindness</p> Signup and view all the answers

    What treatment is currently recommended for serious Neisseria gonorrhoeae infections?

    <p>Cefixime or ceftriaxone</p> Signup and view all the answers

    Which of the following statements about Moraxella species is true?

    <p>They are primarily associated with respiratory illnesses.</p> Signup and view all the answers

    What is the function of OPA proteins in Neisseria gonorrhoeae?

    <p>They assist in the adhesion of gonococci.</p> Signup and view all the answers

    How does Neisseria meningitidis differ from Neisseria gonorrhoeae?

    <p>Neisseria meningitidis ferments maltose, whereas Neisseria gonorrhoeae cannot.</p> Signup and view all the answers

    In which situations is Neisseria meningitidis most likely to cause an outbreak?

    <p>In college dorms and military camps.</p> Signup and view all the answers

    What is a significant risk associated with untreated gonococcal ophthalmia neonatorum?

    <p>Permanent blindness in the infant.</p> Signup and view all the answers

    Study Notes

    Neisseria meningitidis

    • Neisseria meningitidis is a bacterium that can cause serious infections, including meningitis and sepsis.
    • It is commonly found in the nasopharynx of healthy individuals.
    • Outbreaks of Neisseria meningitidis are more likely to occur in crowded living conditions, such as dormitories or military barracks.

    Endocervical Infections in Females

    • The primary cause of endocervical infections in females is Neisseria gonorrhoeae, a sexually transmitted bacterium.

    Neisseria gonorrhoeae Infections

    • The current recommendation for treating Neisseria gonorrhoeae infections is dual therapy with ceftriaxone and azithromycin.

    Eikenella corrodens

    • Eikenella corrodens is a bacterium known for its characteristic "pitting" effect on agar plates during laboratory culture.

    Gonococcal Ophthalmia Neonatorum

    • Untreated gonococcal ophthalmia neonatorum can lead to serious complications, including blindness.

    Neisseria gonorrhoeae vs. Neisseria meningitidis

    • Neisseria gonorrhoeae is typically associated with sexually transmitted infections, while Neisseria meningitidis is more commonly linked to respiratory infections and meningitis.

    Eikenella corrodens: Incorrect Statement

    • Eikenella corrodens does not typically cause skin infections. It is more commonly associated with infections in the mouth, head, and neck.

    Neisseria meningitidis Epidemics

    • Neisseria meningitidis is more prone to epidemic outbreaks in crowded settings with close contact among individuals, such as schools or military camps.

    Untreated Gonococcal Ophthalmia Neonatorum

    • The primary outcome of untreated gonococcal ophthalmia neonatorum is corneal ulceration and potential blindness.

    Serious Neisseria gonorrhoeae Infections

    • The current treatment recommendation for serious Neisseria gonorrhoeae infections includes intravenous ceftriaxone.

    HACEK Bacteria

    • Eikenella corrodens is a small, fastidious gram-negative rod found in the gingival and bowel flora.
    • Eikenella corrodens is oxidase-positive and does not ferment carbohydrates.
    • Eikenella corrodens has an ammonia odor.
    • Eikenella corrodens is commonly found in wounds caused by human bites.

    Moraxella species

    • Moraxella species are coccobacilli associated with bronchitis and pneumonia.

    Neisseria Species

    • Neisseria gonorrhoeae and Neisseria meningitidis are important pathogenic Neisseria species.

    Neisseria meningitidis

    • Neisseria meningitidis is a capsulated bacterium that is part of the normal upper respiratory flora.
    • Neisseria meningitidis ferments maltose and is the leading cause of bacterial meningitis in adults.
    • Neisseria meningitidis has 13 serogroups and vaccines are available to protect against them.
    • Humans are the natural host for Neisseria meningitidis.
    • The nasopharynx is the portal of entry for Neisseria meningitidis.
    • Meningococcal lipopolysaccharides are responsible for the toxic effects of Neisseria meningitidis infection.
    • Neisseria meningitidis infection can progress to coma.

    Neisseria gonorrhoeae

    • Neisseria gonorrhoeae is the causative agent of gonorrhea, a sexually transmitted disease.
    • Neisseria gonorrhoeae does not have a capsule and is unable to ferment maltose.
    • Neisseria gonorrhoeae has pili (hair-like structures) that aid in adhesion.
    • Neisseria gonorrhoeae infects the genitourinary tract, eye, and rectum.
    • Men with gonorrhea often experience a creamy, yellow discharge.
    • In women, Neisseria gonorrhoeae primarily infects the endocervix, which can extend to the vagina.
    • Gonorrhea can lead to septic arthritis.
    • Penicillin is no longer an effective treatment for gonorrhea. Current treatment options include cefixime and ceftriaxone.

    Epidemics

    • Outbreaks of Neisseria meningitidis infection can occur in epidemic waves, particularly in crowded settings like college dorms and military camps.
    • While penicillin is the primary treatment for Neisseria meningitidis infection, it is not always sufficient to eradicate the bacteria. Co-treatment with rifampin or ciprofloxacin is often necessary.

    Gonococcal Ophthalmia Neonatorum

    • Gonococcal ophthalmia neonatorum is a condition that occurs when a newborn is infected with Neisseria gonorrhoeae during passage through the infected birth canal.
    • Untreated gonococcal ophthalmia neonatorum can cause blindness.

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    Description

    This quiz covers HACEK bacteria, including Eikenella corrodens, Moraxella species, and Neisseria species. Learn about their characteristics, infections they cause, and their significance in clinical microbiology. Test your knowledge on these important pathogens and their effects on human health.

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