Grade 12 Biotechnology: Genetic Engineering
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Questions and Answers

What is the primary concern regarding the use of viral vectors in gene therapy?

  • The vectors may recover disease-causing ability (correct)
  • The vectors may not be able to transfect all cells in the body
  • The vectors may only be able to transfect cells in vitro
  • The vectors may not be able to express the gene of interest

    • What is the main reason why repetitive rounds of gene therapy are often ineffective?

  • The gene of interest is not compatible with the host genome
  • The gene therapy is not specific to the target cells
  • The immune response reduces gene therapy effectiveness (correct)
  • The gene therapy is not able to achieve long-term benefits

    • What type of gene therapy involves introducing a healthy copy of a gene to replace a deleted or mutated gene?

  • Gene augmentation
  • Gene ablation
  • Gene correction
  • Gene transplantation (correct)

    • What is a major challenge in developing gene therapy for multi-gene disorders?

    <p>The complexity of the genetic causes of the disorder</p> Signup and view all the answers

    What is the current status of human gene therapy products according to the FDA?

    <p>No products have been approved for sale</p> Signup and view all the answers

    What is the goal of gene ablation in gene therapy?

    <p>To inhibit the expression of a gene</p> Signup and view all the answers

    What is a common issue with gene therapy in achieving long-term benefits?

    <p>Short-lived nature of the gene therapy</p> Signup and view all the answers

    What is the purpose of gene correction in gene therapy?

    <p>To correct a specific mutation in a gene</p> Signup and view all the answers

    What is a major concern with gene therapy in treating multi-gene disorders?

    <p>The complexity of the genetic causes of the disorder</p> Signup and view all the answers

    What is the purpose of gene augmentation in gene therapy?

    <p>To enhance the expression of a gene</p> Signup and view all the answers

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