Glucokinase vs
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Questions and Answers

Which hexokinase(s) are allosterically inhibited by the product G6P?

  • Hexokinase III only
  • Hexokinase I only
  • Hexokinase I, II, and III (correct)
  • Hexokinase II only
  • Which hexokinase is not allosterically inhibited by the product G6P?

  • Hexokinase II
  • Hexokinase III
  • Glucokinase (correct)
  • Hexokinase I
  • What is the function of allosteric inhibition of hexokinases by G6P?

  • To promote insulin secretion
  • To promote liver accumulation of glucose stores (correct)
  • To promote peripheral glucose utilization
  • To promote glucose synthesis
  • Which hexokinase is an inducible enzyme?

    <p>Glucokinase</p> Signup and view all the answers

    What effect does insulin have on the amount of glucokinase?

    <p>Insulin increases the amount of glucokinase</p> Signup and view all the answers

    What is the role of glucokinase in the liver?

    <p>To promote liver accumulation of glucose stores</p> Signup and view all the answers

    What is the main difference between the allosteric regulation of hexokinases and glucokinase?

    <p>Hexokinases are allosterically inhibited by G6P, while glucokinase is not.</p> Signup and view all the answers

    What is the purpose of promoting transcription of the glucokinase gene by insulin?

    <p>To increase glucose storage in the liver</p> Signup and view all the answers

    What is the significance of the allosteric regulation of hexokinases and glucokinase?

    <p>It ensures glucose is only used when needed</p> Signup and view all the answers

    What is the effect of insulin on the activity of glucokinase?

    <p>Insulin has no effect on the activity of glucokinase</p> Signup and view all the answers

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