Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

Glucokinase Roles in Liver and Pancreatic Cells

18 Questions

0 Views

Glucokinase Roles in Liver and Pancreatic Cells

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which molecule makes PFK activity more responsive to substrate?

F-2,6-BP (correct)

ATP

AMP

ADP

Which enzyme catalyzes an irreversible step in the glycolytic pathway with no meaningful back-reaction?

FBPase

Aldolase

Enzyme f

PFK (correct)

What effect does F-2,6-BP have on PFK activity in relation to ATP and FBPase?

Decreases the inhibitory effects of ATP and stimulates FBPase activity

Decreases the inhibitory effects of ATP and opposes FBPase activity (correct)

Increases the inhibitory effects of ATP and stimulates FBPase activity

Opposes the inhibitory effects of ATP and stimulates FBPase activity

What role does substrate cycling play in the glycolytic pathway?

It enhances the regulation of enzyme activities Signup and view all the answers

Which molecules act as 'brakes' in regulating enzyme activities within the glycolytic pathway?

ADP and AMP Signup and view all the answers

What type of regulation is described when enzymes within the glycolytic pathway are allosterically regulated by effectors like gas and brake pedals?

Allosteric regulation Signup and view all the answers

What is the role of F-2,6-BP in the regulation of PFK?

Activates PFK Signup and view all the answers

How does ATP affect PFK regulation?

Inhibits PFK Signup and view all the answers

What is the main function of substrate cycling in glycolysis?

To maintain metabolic balance Signup and view all the answers

How is FBPase regulated in the glycolytic pathway?

Inhibition by ATP Signup and view all the answers

Which statement best describes enzyme allosteric regulation?

It can occur even with high substrate concentrations Signup and view all the answers

How does AMP affect enzyme activity in the glycolytic pathway?

Activates enzyme activity Signup and view all the answers

What is the major rate-determining step in glycolysis?

Conversion of F6P to FBP by PFK Signup and view all the answers

What inhibits phosphofructokinase (PFK) activity, indicating high energy levels in the cell?

ATP Signup and view all the answers

What is the regulatory molecule that stimulates phosphofructokinase (PFK) activity?

AMP Signup and view all the answers

Which statement describes the allosteric regulation of PFK accurately?

ATP inhibits PFK by binding to the regulatory site, promoting the R state. Signup and view all the answers

What is the role of fructose-2,6-bisphosphate in regulating phosphofructokinase (PFK)?

It enhances PFK activity by acting as an allosteric activator. Signup and view all the answers

Which molecule has the highest potential to stimulate a significant increase in phosphofructokinase (PFK) activity?

$102$-fold increase in ATP levels Signup and view all the answers