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Genetic Designs in Traditional Genetics

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what are the 3 types of traditional genetic designs?

adoption studies, twin studies and family studies

describe twin studies

twin studies observe the effects of different environments on identical genotypes and the levels of gene expression in different environments

explain adoption studies

adoption studies observe the similarities between adopted children and their biological parents, who do not share the same environment

explain family studies:

family studies compare low-risk controls to high-risk children to determine the environmental effect on subjects with different levels of genetic risk

what are the two types of gene-environment interaction studies?

molecular analyses and traditional genetic designs

what are the 3 methods of molecular analysis in studying gene-environment interaction?

environmental interactions with single gens, environmental interactions with multiple genes and genome-wide association studies

explain the molecular analysis of interactions with single genes

SNPs are compared with single binary exposure factors to determine any effects

explain the molecular analysis of interactions with multiple genes

using polygenic approaches to analyse single environmental factor interactions with multiple genes

explain genome-wide interaction studies

genome-wide interaction studies examine the interaction between the environment and a large number of independent SNPs.

explain model A of a gene-environment interaction

the genotype produces or increases the expression of an environmental risk factor that can also be produced non-genetically

Test your knowledge of traditional genetic designs! This quiz covers the three main types of genetic designs, their applications, and advantages. Take the quiz to see how well you understand the fundamentals of genetics.

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