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Gastrointestinal Medications: Chapter 37 Overview of Peptic Ulcer Disease and GERD

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28 Questions

What is the primary mechanism by which Helicobacter pylori bacteria cause peptic ulcer disease?

By inhibiting the production of protective mucus layers

Which of the following medications is most likely to interact with multiple drugs?

Cimetidine

What is the primary benefit of taking proton pump inhibitors on an empty stomach?

To enhance the efficacy of the medication

Which of the following is a characteristic of duodenal ulcers?

All of the above

What is the primary purpose of using misoprostol with NSAIDs?

To prevent NSAID-induced peptic ulcers

What is the primary mechanism of action of antacids?

Neutralization of gastric acid

What is the primary mechanism of action of sucralfate in treating nausea and vomiting?

It binds to the gastric mucosa

Which of the following is a common side effect of phenothiazines, such as promethazine?

Anticholinergic effects

What is the primary indication for the use of ondansetron?

Moderate to severe nausea and vomiting in chemotherapy

Which of the following medications is a surfactant laxative?

Docusate

What is the primary mechanism of action of bulk-forming laxatives such as psyllium?

Increasing the bulk of the stool

Which of the following medications is an anti-histamine H-1 receptor blocker?

Hydroxyzine

What is the primary mechanism of phenothiazines in treating nausea and vomiting?

Blocks dopamine receptors

Which type of laxative increases the bulk of stool, making it easier to pass?

Bulk-forming laxative

What is the primary benefit of using anti-histamines in treating nausea and vomiting?

Antagonizes H-1 receptors

Which type of medication is commonly used to treat moderate to severe nausea and vomiting?

Serotonin receptor antagonists

What is the primary mechanism of sucralfate in treating nausea and vomiting?

Binds to the gastric mucosa

Which type of laxative decreases the surface tension of stool, making it easier to pass?

Surfactant laxative

What is the primary characteristic of constipation?

Infrequent and painful expulsion of hard, dry stools

What is the primary mechanism of stimulant laxatives in treating constipation?

Increase gut motility

What is the primary cause of peptic ulcer disease and GERD?

Overproduction of gastric acid and pepsin

Which of the following is a major risk factor for peptic ulcer disease?

Cigarette smoking

What is the primary difference between antacids and histamine-2 receptor antagonists?

Antacids neutralize acid, while histamine-2 receptor antagonists reduce acid production

Which of the following medications is used to prevent ulcers when taking NSAIDs?

Misoprostol

What is the primary benefit of using proton pump inhibitors?

They reduce acid production

Which of the following is a characteristic of gastric ulcers?

Pain worsens with food intake

What is the primary advantage of famotidine over cimetidine?

Famotidine is less likely to interact with other drugs

Which of the following medications is used to treat both peptic ulcer disease and GERD?

All of the above

Test your knowledge on gastrointestinal medications, specifically on peptic ulcer disease and GERD, including pathophysiology, causes, and treatment options. This chapter covers the basics of peptic ulcer disease, NSAID use, Helicobacter pylori, stress, and gastric acid and pepsin. Assess your understanding of the drugs used to treat these conditions.

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