Podcast
Questions and Answers
Which medication is used for tonic–clonic seizures and to prevent seizure activity in patients during and following neurosurgery and brain injury?
Which medication is used for tonic–clonic seizures and to prevent seizure activity in patients during and following neurosurgery and brain injury?
- Lamotrigine
- Carbamazepine
- Phenytoin (correct)
- Gabapentin
Which medication's common adverse effects include CNS depression, dizziness, somnolence, insomnia, and ataxia?
Which medication's common adverse effects include CNS depression, dizziness, somnolence, insomnia, and ataxia?
- Gabapentin (correct)
- Topiramate
- Phenytoin
- Valproic acid
Which medication has contraindications related to known hypersensitivity to the medication and known hypersensitivity to the hydantoins, seizures related to hypoglycemia, sinus bradycardia, heart block, and Stokes-Adams syndrome?
Which medication has contraindications related to known hypersensitivity to the medication and known hypersensitivity to the hydantoins, seizures related to hypoglycemia, sinus bradycardia, heart block, and Stokes-Adams syndrome?
- Phenytoin (correct)
- Gabapentin
- Oxcarbazepine
- Pregabalin
Which medication's nursing assessment includes monitoring for absence of partial seizures and changes in mood and personality?
Which medication's nursing assessment includes monitoring for absence of partial seizures and changes in mood and personality?
Which medication's IV administration can result in cardiovascular collapse, requiring close monitoring of cardiovascular status?
Which medication's IV administration can result in cardiovascular collapse, requiring close monitoring of cardiovascular status?
Which medication requires caution in older adults and patients with renal or hepatic impairment?
Which medication requires caution in older adults and patients with renal or hepatic impairment?
Which medication's interactions include antacids and Ginkgo biloba affecting absorption?
Which medication's interactions include antacids and Ginkgo biloba affecting absorption?
Which medication's interactions include corticosteroids, oral contraceptives, and nisoldipine, as well as decreased absorption of folic acid, calcium, and vitamin D?
Which medication's interactions include corticosteroids, oral contraceptives, and nisoldipine, as well as decreased absorption of folic acid, calcium, and vitamin D?
Which medication can be taken orally with food to prevent GI upset?
Which medication can be taken orally with food to prevent GI upset?
Which medication's nursing assessment includes monitoring for absence of tonic–clonic and psychomotor seizures, skin eruption indicative of hypersensitivity reaction, and cardiovascular collapse with IV administration?
Which medication's nursing assessment includes monitoring for absence of tonic–clonic and psychomotor seizures, skin eruption indicative of hypersensitivity reaction, and cardiovascular collapse with IV administration?
Which medication stabilizes neuronal membrane by delaying sodium influx?
Which medication stabilizes neuronal membrane by delaying sodium influx?
Which medication has increased risk of osteoporosis as a common adverse effect?
Which medication has increased risk of osteoporosis as a common adverse effect?
What is the primary use of gabapentin?
What is the primary use of gabapentin?
Where does gabapentin metabolism occur?
Where does gabapentin metabolism occur?
What is the peak time for gabapentin?
What is the peak time for gabapentin?
How does gabapentin exert its antiepileptic action?
How does gabapentin exert its antiepileptic action?
What is the recommended dosage of gabapentin for a patient with CrCl of 40 mL/min?
What is the recommended dosage of gabapentin for a patient with CrCl of 40 mL/min?
What is the off-label use of gabapentin?
What is the off-label use of gabapentin?
Where does gabapentin bind in the body?
Where does gabapentin bind in the body?
What is the range for reduced daily dose in proportion to CrCl for a patient with CrCl < 15 mL/min?
What is the range for reduced daily dose in proportion to CrCl for a patient with CrCl < 15 mL/min?
What is the effect of gabapentin on breast milk?
What is the effect of gabapentin on breast milk?
What is gabapentin structurally related to?
What is gabapentin structurally related to?
What is the primary use of gabapentin in patients with impaired renal function?
What is the primary use of gabapentin in patients with impaired renal function?
What is the primary use of gabapentin in patients with hepatic impairment?
What is the primary use of gabapentin in patients with hepatic impairment?
What is the primary use of gabapentin?
What is the primary use of gabapentin?
Where does gabapentin metabolism occur?
Where does gabapentin metabolism occur?
What is the effect of gabapentin on breast milk?
What is the effect of gabapentin on breast milk?
What is the range for reduced daily dose in proportion to CrCl for a patient with CrCl < 15 mL/min?
What is the range for reduced daily dose in proportion to CrCl for a patient with CrCl < 15 mL/min?
What is gabapentin structurally related to?
What is gabapentin structurally related to?
Where does gabapentin bind in the body?
Where does gabapentin bind in the body?
What is the peak time for gabapentin?
What is the peak time for gabapentin?
Where does metabolism of gabapentin occur?
Where does metabolism of gabapentin occur?
What is the primary action of gabapentin related to its antiepileptic effect?
What is the primary action of gabapentin related to its antiepileptic effect?
For which condition was gabapentin initially approved by the FDA?
For which condition was gabapentin initially approved by the FDA?
In patients with renal impairment, what is the recommended dosage adjustment for a creatinine clearance (CrCl) of 15 mL/min?
In patients with renal impairment, what is the recommended dosage adjustment for a creatinine clearance (CrCl) of 15 mL/min?
What are some off-label uses of gabapentin?
What are some off-label uses of gabapentin?
How does gabapentin enter the body of a breastfeeding mother?
How does gabapentin enter the body of a breastfeeding mother?
What is gabapentin's relationship to GABA?
What is gabapentin's relationship to GABA?
For patients with impaired renal function and a CrCl of 60 mL/min, what is the recommended dosage of gabapentin?
For patients with impaired renal function and a CrCl of 60 mL/min, what is the recommended dosage of gabapentin?
In patients with hepatic impairment, what dosage adjustment is required?
In patients with hepatic impairment, what dosage adjustment is required?
What is the primary use of gabapentin as an adjunctive treatment?
What is the primary use of gabapentin as an adjunctive treatment?
What is the primary use of gabapentin for which the FDA approved it in May of 2002?
What is the primary use of gabapentin for which the FDA approved it in May of 2002?
Study Notes
Antiepileptic Medications: Gabapentin and Phenytoin
- Gabapentin: common adverse effects include CNS depression, dizziness, somnolence, insomnia, and ataxia
- Gabapentin: contraindications include known hypersensitivity to the medication
- Gabapentin: interactions with antacids and Ginkgo biloba affect absorption
- Gabapentin: administered orally, can be taken with food to prevent GI upset
- Gabapentin: nursing assessment includes monitoring for absence of partial seizures and changes in mood and personality
- Phenytoin: stabilizes neuronal membrane by delaying sodium influx, used for tonic–clonic seizures and to prevent seizure activity in patients during and following neurosurgery and brain injury
- Phenytoin: caution required in older adults and patients with renal or hepatic impairment
- Phenytoin: IV administration can result in cardiovascular collapse, requires close monitoring of cardiovascular status
- Phenytoin: common adverse effects include CNS and GI effects, gingival hyperplasia, and increased risk of osteoporosis
- Phenytoin: contraindications include known hypersensitivity to the hydantoins, seizures related to hypoglycemia, sinus bradycardia, heart block, and Stokes-Adams syndrome
- Phenytoin: interactions with corticosteroids, oral contraceptives, and nisoldipine, as well as decreased absorption of folic acid, calcium, and vitamin D
- Phenytoin: nursing assessment includes monitoring for absence of tonic–clonic and psychomotor seizures, skin eruption indicative of hypersensitivity reaction, and cardiovascular collapse with IV administration
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Description
Test your knowledge of antiepileptic medications with this quiz on Gabapentin and Phenytoin. Learn about their adverse effects, contraindications, drug interactions, administration, and nursing assessments.
