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Questions and Answers
What is the primary mechanism of action for carbamazepine, oxcarbazepine, and eslicarbazepine?
What is the primary mechanism of action for carbamazepine, oxcarbazepine, and eslicarbazepine?
- Enhancing cholinergic activity in the brain
- Inhibiting the reuptake of serotonin and norepinephrine
- Affecting sodium channels and slowing sodium influx in cortical neurons (correct)
- Blocking GABA receptors in the central nervous system
Which area of the brain is associated with the spread of seizure discharge, and is affected by carbamazepine?
Which area of the brain is associated with the spread of seizure discharge, and is affected by carbamazepine?
- Substantia nigra
- Nucleus accumbens
- Locus coeruleus
- Nucleus ventralis anterior of the thalamus (correct)
Which of the following is NOT one of the additional actions of carbamazepine mentioned in the text?
Which of the following is NOT one of the additional actions of carbamazepine mentioned in the text?
- Antidysrhythmic activity
- Antidiuretic activity
- Antipsychotic activity (correct)
- Anticholinergic activity
How is carbamazepine absorbed in the body?
How is carbamazepine absorbed in the body?
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What is the reason given for the slow and erratic absorption of carbamazepine from immediate-release tablets?
What is the reason given for the slow and erratic absorption of carbamazepine from immediate-release tablets?
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What is the protein binding percentage of oxcarbazepine and its active metabolite, respectively?
What is the protein binding percentage of oxcarbazepine and its active metabolite, respectively?
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