6 Questions
What is the primary mechanism of action for carbamazepine, oxcarbazepine, and eslicarbazepine?
Affecting sodium channels and slowing sodium influx in cortical neurons
Which area of the brain is associated with the spread of seizure discharge, and is affected by carbamazepine?
Nucleus ventralis anterior of the thalamus
Which of the following is NOT one of the additional actions of carbamazepine mentioned in the text?
Antipsychotic activity
How is carbamazepine absorbed in the body?
Through the stomach, with the suspension being absorbed more quickly than the tablet form
What is the reason given for the slow and erratic absorption of carbamazepine from immediate-release tablets?
Its low water solubility
What is the protein binding percentage of oxcarbazepine and its active metabolite, respectively?
67% and 40%
Test your knowledge about antiepileptic medications such as Carbamazepine (Tegretol), Oxcarbazepine (Trileptal, Oxtellar XR), and Eslicarbazepine (Aptiom). Learn about their uses in treating epilepsy, bipolar affective disorder, neuralgias, and more. Understand the pharmacodynamics of these iminostilbene derivatives.
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