Antiepileptic Medications Quiz
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Questions and Answers

What is the primary mechanism of action for carbamazepine, oxcarbazepine, and eslicarbazepine?

  • Enhancing cholinergic activity in the brain
  • Inhibiting the reuptake of serotonin and norepinephrine
  • Affecting sodium channels and slowing sodium influx in cortical neurons (correct)
  • Blocking GABA receptors in the central nervous system
  • Which area of the brain is associated with the spread of seizure discharge, and is affected by carbamazepine?

  • Substantia nigra
  • Nucleus accumbens
  • Locus coeruleus
  • Nucleus ventralis anterior of the thalamus (correct)
  • Which of the following is NOT one of the additional actions of carbamazepine mentioned in the text?

  • Antidysrhythmic activity
  • Antidiuretic activity
  • Antipsychotic activity (correct)
  • Anticholinergic activity
  • How is carbamazepine absorbed in the body?

    <p>Through the stomach, with the suspension being absorbed more quickly than the tablet form</p> Signup and view all the answers

    What is the reason given for the slow and erratic absorption of carbamazepine from immediate-release tablets?

    <p>Its low water solubility</p> Signup and view all the answers

    What is the protein binding percentage of oxcarbazepine and its active metabolite, respectively?

    <p>67% and 40%</p> Signup and view all the answers

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