Fluoroquinolones Precautions and Side Effects

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What is the recommended duration for parenteral treatment with aminoglycosides like gentamicin?

Parenteral treatment should not exceed 3 days wherever possible
Parenteral treatment should not exceed 7 days wherever possible (correct)
Parenteral treatment should not exceed 30 days wherever possible
Parenteral treatment should not exceed 14 days wherever possible

What is the recommended approach for dose adjustments in patients with renal impairment?

Discontinue the medication in patients with renal impairment
Decrease the dose interval based on the severity of renal impairment
Maintain the same dose interval regardless of renal impairment
Increase the dose interval based on the severity of renal impairment (correct)

When should serum concentrations of aminoglycosides be monitored?

Serum concentrations should be monitored in all patients receiving aminoglycosides (correct)
Serum concentrations should only be monitored in elderly patients
Serum concentrations should only be monitored in patients with renal impairment
Serum concentrations should only be monitored in patients receiving high doses

What is the recommended timing for collecting blood samples to monitor aminoglycoside levels?

Collect samples both one hour after administration ('peak') and just before the next dose ('trough') (A) Signup and view all the answers

Which of the following interactions with aminoglycosides can lead to ototoxicity?

Interaction with loop diuretics like furosemide (B) Signup and view all the answers

What is a common side effect of aminoglycosides like gentamicin?

Nephrotoxicity (A) Signup and view all the answers

Which of the following is a contraindication for the use of quinolones?

History of tendon damage associated with quinolone use (C) Signup and view all the answers

What precaution should be taken when using quinolones?

Avoid exposure to excessive sunlight, as quinolones can cause photosensitivity (C) Signup and view all the answers

Which of the following groups should avoid the use of quinolones?

Children and growing adolescents, as quinolones can cause arthropathy (C) Signup and view all the answers

Which of the following medications should be avoided when taking quinolones due to the risk of prolonging the QT interval and increasing the risk of arrhythmias?

Amiodarone (C) Signup and view all the answers

Which of the following statements is true regarding the administration of quinolones?

Quinolones should be taken on an empty stomach, avoiding milk, antacids, iron, or zinc supplements 2 hours before or after the dose (A) Signup and view all the answers

Which of the following adverse effects may occur with quinolone use, requiring discontinuation of the drug?

Psychiatric reactions, such as hallucinations (D) Signup and view all the answers

Which of the following is a potential side effect of tetracycline antibiotics?

Discoloration of tooth enamel in children (A) Signup and view all the answers

What is a potential interaction to be aware of with tetracycline antibiotics?

They can interact with divalent cations like iron and calcium, preventing their absorption. (C) Signup and view all the answers

Which of the following is a contraindication for tetracycline antibiotics?

Pregnancy and breastfeeding (C) Signup and view all the answers

What is a potential side effect of trimethoprim, a folate antagonist antibiotic?

Blood disorders (A) Signup and view all the answers

Which of the following is a precaution to be taken with tetracycline antibiotics?

Avoid exposure to sunlight, especially with doxycycline and demeclocycline, due to photosensitivity. (B) Signup and view all the answers

Which of the following is a contraindication for trimethoprim during pregnancy?

It should be avoided throughout pregnancy due to its teratogenic and folate antagonist effects. (A) Signup and view all the answers