18 Questions
What is the recommended duration for parenteral treatment with aminoglycosides like gentamicin?
Parenteral treatment should not exceed 7 days wherever possible
What is the recommended approach for dose adjustments in patients with renal impairment?
Increase the dose interval based on the severity of renal impairment
When should serum concentrations of aminoglycosides be monitored?
Serum concentrations should be monitored in all patients receiving aminoglycosides
What is the recommended timing for collecting blood samples to monitor aminoglycoside levels?
Collect samples both one hour after administration ('peak') and just before the next dose ('trough')
Which of the following interactions with aminoglycosides can lead to ototoxicity?
Interaction with loop diuretics like furosemide
What is a common side effect of aminoglycosides like gentamicin?
Nephrotoxicity
Which of the following is a contraindication for the use of quinolones?
History of tendon damage associated with quinolone use
What precaution should be taken when using quinolones?
Avoid exposure to excessive sunlight, as quinolones can cause photosensitivity
Which of the following groups should avoid the use of quinolones?
Children and growing adolescents, as quinolones can cause arthropathy
Which of the following medications should be avoided when taking quinolones due to the risk of prolonging the QT interval and increasing the risk of arrhythmias?
Amiodarone
Which of the following statements is true regarding the administration of quinolones?
Quinolones should be taken on an empty stomach, avoiding milk, antacids, iron, or zinc supplements 2 hours before or after the dose
Which of the following adverse effects may occur with quinolone use, requiring discontinuation of the drug?
Psychiatric reactions, such as hallucinations
Which of the following is a potential side effect of tetracycline antibiotics?
Discoloration of tooth enamel in children
What is a potential interaction to be aware of with tetracycline antibiotics?
They can interact with divalent cations like iron and calcium, preventing their absorption.
Which of the following is a contraindication for tetracycline antibiotics?
Pregnancy and breastfeeding
What is a potential side effect of trimethoprim, a folate antagonist antibiotic?
Blood disorders
Which of the following is a precaution to be taken with tetracycline antibiotics?
Avoid exposure to sunlight, especially with doxycycline and demeclocycline, due to photosensitivity.
Which of the following is a contraindication for trimethoprim during pregnancy?
It should be avoided throughout pregnancy due to its teratogenic and folate antagonist effects.
Learn about the precautions and potential side effects associated with fluoroquinolones, including tendon damage, photosensitivity, QT interval prolongation, arthropathy, and neurological reactions. Understand the specific patient populations that require caution when using these antibiotics.
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