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Questions and Answers
What is a common clinical sign of diabetes mellitus?
What is a common clinical sign of diabetes mellitus?
Which diagnostic test is most directly linked to the presence of glucose in urine?
Which diagnostic test is most directly linked to the presence of glucose in urine?
What pathogenesis mechanism is associated with impaired insulin secretion during diabetes mellitus?
What pathogenesis mechanism is associated with impaired insulin secretion during diabetes mellitus?
Which of the following describes a change in liver appearance due to diabetes mellitus?
Which of the following describes a change in liver appearance due to diabetes mellitus?
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Which of the following is NOT a clinical sign associated with diabetes mellitus?
Which of the following is NOT a clinical sign associated with diabetes mellitus?
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What type of inflammation is characterized by the presence of dark orange thick exudate?
What type of inflammation is characterized by the presence of dark orange thick exudate?
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What condition is indicated by the presence of bilirubin in urine?
What condition is indicated by the presence of bilirubin in urine?
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What effect does prolonged hyperglycemia have on glucose transporters?
What effect does prolonged hyperglycemia have on glucose transporters?
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Which symptom indicates increased sensitivity to stimuli such as touch and sound?
Which symptom indicates increased sensitivity to stimuli such as touch and sound?
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What lesions are localized in the lymph nodes, kidneys, uvea, and meninges?
What lesions are localized in the lymph nodes, kidneys, uvea, and meninges?
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Which process is primarily responsible for the damage to the pancreas in diabetes mellitus?
Which process is primarily responsible for the damage to the pancreas in diabetes mellitus?
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Which of the following describes intention tremors?
Which of the following describes intention tremors?
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Cranial nerve deficits are commonly associated with what type of neurological issues?
Cranial nerve deficits are commonly associated with what type of neurological issues?
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Which organ shows plaques located at the apex as a clinical feature?
Which organ shows plaques located at the apex as a clinical feature?
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Which type of hypersensitivity reaction is associated with vasculitis?
Which type of hypersensitivity reaction is associated with vasculitis?
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What is a common clinical manifestation of multifocal fibrinous peritonitis?
What is a common clinical manifestation of multifocal fibrinous peritonitis?
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What is a common histological feature used to identify amyloid deposits in islets?
What is a common histological feature used to identify amyloid deposits in islets?
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Which clinical sign is associated with feline infectious peritonitis?
Which clinical sign is associated with feline infectious peritonitis?
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What is one of the pathological characteristics of Feline Infectious Peritonitis (FIP)?
What is one of the pathological characteristics of Feline Infectious Peritonitis (FIP)?
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Peripheral insulin resistance can be caused by which condition related to fat?
Peripheral insulin resistance can be caused by which condition related to fat?
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What is the main underlying cause of Feline Infectious Peritonitis?
What is the main underlying cause of Feline Infectious Peritonitis?
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Which of the following describes a significant determining factor in the pathogenesis of insulin resistance?
Which of the following describes a significant determining factor in the pathogenesis of insulin resistance?
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Which of the following is true about the types of feline infectious peritonitis?
Which of the following is true about the types of feline infectious peritonitis?
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What kind of changes occur in the pancreatic islets due to amyloid deposition?
What kind of changes occur in the pancreatic islets due to amyloid deposition?
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Flashcards
Diabetes Mellitus
Diabetes Mellitus
A condition where the body cannot properly regulate blood sugar levels due to either insufficient insulin production or resistance to insulin's effects.
Glucosuria
Glucosuria
Increased sugar concentration in the urine, indicating a problem with blood glucose regulation.
Amyloidosis
Amyloidosis
A complex protein found in various tissues, including the liver, kidneys, and pancreas. In diabetes, it can accumulate abnormally, contributing to organ damage.
Ascites
Ascites
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Hypoalbuminemia
Hypoalbuminemia
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Bilirubinemia
Bilirubinemia
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Glucose Toxicity
Glucose Toxicity
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Impaired Insulin Secretion
Impaired Insulin Secretion
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Amyloid Deposition in Islets
Amyloid Deposition in Islets
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Triditis
Triditis
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Lipotoxicity
Lipotoxicity
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Beta Cell Death
Beta Cell Death
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Peripheral Insulin Resistance
Peripheral Insulin Resistance
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Feline Infectious Peritonitis (FIP) Virus
Feline Infectious Peritonitis (FIP) Virus
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Histopathology
Histopathology
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Lesions around Blood Vessels in Kidney
Lesions around Blood Vessels in Kidney
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Granulomatous inflammation
Granulomatous inflammation
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Dark orange thick exudate
Dark orange thick exudate
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Inflamed capsule of the liver
Inflamed capsule of the liver
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Multifocal hard nodules
Multifocal hard nodules
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Plaques located on the apex of the heart
Plaques located on the apex of the heart
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Fibrin-inflamed capsule of the liver
Fibrin-inflamed capsule of the liver
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Incoordination
Incoordination
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Intention tremors
Intention tremors
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Study Notes
Diabetes Mellitus
- Lesions: Diffuse tan coloring of the liver, enlarged liver, fat overtaken tubules, fat accumulation in cells
- Clinical signs: Glucosuria (glucose in urine), bilirubinuria (bilirubin in urine), hypoalbuminemia (low albumin), bilirubinemia (high bilirubin), ascites (fluid accumulation in abdomen)
- Pathogenesis/causes: Glucose toxicity (prolonged high blood sugar), downregulation of glucose transporters on beta cells, impaired insulin secretion, lipotoxicity (high serum fatty acids suppressing insulin secretion), glycogen accumulation, cell dearth
- Diagnosis: Blood tests (urine and/or blood), fructosamine test
Feline Infectious Peritonitis
- Lesions: Atrophy of kidney, tan cortex with multifocal raised lesions, lesions around blood vessels in kidney, dark orange thick exudate, multifocal hard nodules, inflamed capsule of liver, multifocal fibrinous peritonitis, hepatomegaly, round firm foci on the serosal surface of organs, plaques located on apex of heart, fibrin inflamed capsule of liver, vasculitis, necrosis, macrophages
- Clinical signs: Ataxia (loss of bodily control), nystagmus (involuntary eye movements), seizures, incoordination, intention tremors, hyperesthesia (increased sensitivity), behavior changes, cranial nerve deficits, head tilt
- Pathogenesis/causes: Mutated form of feline enteric coronavirus (FCoV), effusive (wet) or non-effusive (dry) form, high protein exudate or modified transudate, granulomatous inflammation, type 3 hypersensitivity reaction with vasculitis.
- Diagnosis: Histopathology (if pathognomonic lesions), detection of intracellular FCoV antigen (immunofluorescence or immunohistochemistry), RT-PCR (reverse transcriptase-polymerase chain reaction).
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Description
Test your knowledge on the causes, symptoms, and diagnosis of Diabetes Mellitus and Feline Infectious Peritonitis. This quiz covers essential clinical signs, pathogenesis, and lesions associated with these conditions. Enhance your understanding of feline health and disease.