Podcast
Questions and Answers
Which receptor does FIV Env bind to initiate infection?
Which receptor does FIV Env bind to initiate infection?
What is the function of reverse transcriptase in FIV replication?
What is the function of reverse transcriptase in FIV replication?
What is the most common FIV subtype?
What is the most common FIV subtype?
Study Notes
- Understanding virus structure and replication informs diagnostic testing and persistent infection outcome.
- FIV virion contains duplicate, single-stranded RNA genome.
- Three major genes encode viral core proteins, enzymes, and envelope glycoproteins.
- Env binds primary receptor CD134 to initiate infection and co-receptor CXCR4 for cell entry.
- Viral genome is released and copied into DNA by reverse transcriptase.
- Provirus can remain latent or form template for new virions.
- FIV mutates frequently, creating a pool of variant viruses.
- Phylogenetic classification of FIV into major subtypes or clades A to E.
- Subtype classification is complex and uncertain in predicting biological properties.
- Subtypes A, B, and C are most common with regional variation in prevalence.
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Description
Test your knowledge on Feline Immunodeficiency Virus (FIV) with this informative quiz! Learn about the virus structure and replication, the major genes and proteins involved, and the process of infection and replication. Discover the different subtypes of FIV and their prevalence in different regions. This quiz is perfect for anyone interested in understanding more about this important feline virus.
