Esomeprazole: Uses and Administration
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Questions and Answers

What is the primary action of esomeprazole in the stomach?

  • Neutralizes the acid produced
  • Increases the production of acid
  • Reduces the amount of acid produced (correct)
  • Enhances digestion

    • What is Zollinger-Ellison syndrome?

  • A type of heartburn
  • A type of gastro-oesophageal reflux disease
  • A condition caused by a tumour in the pancreas or gut (correct)
  • A type of stomach ulcer

    • What is the brand name of the medicine that combines esomeprazole with naproxen?

  • Naproxen
  • Gastro-oesophageal reflux disease
  • Esomeprazole
  • Vimovo (correct)

    • After how many days does esomeprazole start to work?

    <p>2 to 3 days</p> Signup and view all the answers

    What is a common side effect of esomeprazole?

    <p>All of the above</p> Signup and view all the answers

    What should you avoid doing if you experience dizziness, sleepiness, or blurred vision while taking esomeprazole?

    <p>All of the above</p> Signup and view all the answers

    Who can take esomeprazole?

    <p>Children under a doctor's prescription</p> Signup and view all the answers

    What can irritate the stomach lining and make symptoms worse?

    <p>Drinking alcohol</p> Signup and view all the answers

    What should you do if you have taken more than your prescribed dose of esomeprazole and experience certain symptoms?

    <p>Contact 111 for advice</p> Signup and view all the answers

    Why should you speak to your doctor before stopping esomeprazole?

    <p>Because stopping suddenly could make your stomach produce a lot more acid</p> Signup and view all the answers

    What is a common side effect of esomeprazole that happens in more than 1 in 100 people?

    <p>Diarrhoea</p> Signup and view all the answers

    What is a sign of a serious allergic reaction to esomeprazole?

    <p>Rash that's swollen, raised, itchy, blistered or peeling</p> Signup and view all the answers

    What may happen if you take esomeprazole for more than 3 months?

    <p>The levels of magnesium in your blood may fall</p> Signup and view all the answers

    What should you do if you experience a side effect that is not going away?

    <p>Speak to a doctor or pharmacist</p> Signup and view all the answers

    What is a rare condition that may occur as a side effect of esomeprazole?

    <p>Subacute cutaneous lupus erythematosus</p> Signup and view all the answers

    Why is esomeprazole not recommended during pregnancy?

    <p>Because there is little information about its use during pregnancy</p> Signup and view all the answers

    What should you do if you experience severe diarrhoea while taking esomeprazole?

    <p>Report it to your doctor</p> Signup and view all the answers

    What is the purpose of regular health checks if you take esomeprazole for longer than 1 year?

    <p>To see if you should carry on taking it</p> Signup and view all the answers

    What should you do if you're going to have an endoscopy while taking esomeprazole?

    <p>Stop taking esomeprazole a few weeks before your procedure</p> Signup and view all the answers

    What is the usual dose of esomeprazole to treat heartburn and acid reflux?

    <p>20mg a day</p> Signup and view all the answers

    What should you do if you have problems swallowing tablets?

    <p>Add the tablets to a glass of water, wait for them to dissolve and then drink it straight away</p> Signup and view all the answers

    Why may your doctor increase your dose of esomeprazole?

    <p>If it's not working well enough</p> Signup and view all the answers

    What should you do if you forget to take your esomeprazole dose and it's less than 12 hours until your next dose?

    <p>Skip the missed dose and take the next one at the usual time</p> Signup and view all the answers

    How often should you take esomeprazole to treat Zollinger-Ellison syndrome?

    <p>Once a day</p> Signup and view all the answers

    What should you do if you take too much esomeprazole?

    <p>It's unlikely to cause any problems</p> Signup and view all the answers

    How long should you take esomeprazole for if you bought it from a pharmacy or supermarket?

    <p>For 2 weeks only</p> Signup and view all the answers

    What is the strength of esomeprazole granules in sachets?

    <p>10mg</p> Signup and view all the answers

    Why may your doctor recommend taking esomeprazole only when you have symptoms?

    <p>Because it's not suitable for everyone</p> Signup and view all the answers

    What percentage of unplanned hospital admissions caused by adverse drug events are preventable among patients over 65 years of age who take five or more medicines?

    <p>50%</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with anticholinergics?

    <p>Confusion</p> Signup and view all the answers

    What is an example of a drug-drug interaction?

    <p>Meropenem and valproate</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with opioids and benzodiazepines?

    <p>Falls</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with diuretics?

    <p>Dehydration</p> Signup and view all the answers

    What is the name of the tool used by pharmacists and other members of clinical teams to determine drug-drug and drug-disease interactions?

    <p>Stockley's Interactions Checker</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with NSAIDs?

    <p>Heart failure</p> Signup and view all the answers

    What is a drug-disease interaction associated with metoclopramide?

    <p>Parkinson's</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with α1-adrenergic receptor antagonists?

    <p>Orthostatic hypotension</p> Signup and view all the answers

    What is a potential adverse drug reaction associated with amitriptyline?

    <p>Arrhythmias</p> Signup and view all the answers

    What is the main reason why doctors may suggest omeprazole instead of esomeprazole?

    <p>There is more safety information available on omeprazole</p> Signup and view all the answers

    What is the likelihood of esomeprazole causing side effects in breastfed babies?

    <p>Unlikely</p> Signup and view all the answers

    Which of the following medicines may affect the way esomeprazole works when taken together?

    <p>Cilostazol, a medicine that treats peripheral arterial disease</p> Signup and view all the answers

    What is the name of the herbal remedy that should not be taken with esomeprazole?

    <p>St John's wort</p> Signup and view all the answers

    What is an example of a pharmacodynamic change in older persons that can affect the action of medication?

    <p>Changes in the neurotransmitter gamma-aminobutyric acid (GABA)</p> Signup and view all the answers

    What is an example of an adaptive homeostatic response that can occur in older persons taking certain medications?

    <p>Increased sensitivity to anti-hypertensives</p> Signup and view all the answers

    What is an example of a pathological change in organs that can affect the action of medication?

    <p>All of the above</p> Signup and view all the answers

    Why should patients inform their doctor if they are trying to get pregnant or are pregnant?

    <p>Because the doctor may want to review their treatment</p> Signup and view all the answers

    What should patients do if they are taking any other medicines, including herbal remedies, vitamins, or supplements?

    <p>Tell their doctor or pharmacist</p> Signup and view all the answers

    What is a consequence of taking esomeprazole with certain medicines that can affect the way it works?

    <p>Increased risk of side effects</p> Signup and view all the answers

    Study Notes

    Esomeprazole

    • Reduces the amount of acid in the stomach
    • Used to treat:
      • Indigestion, heartburn, and acid reflux
      • Gastro-oesophageal reflux disease (GORD)
      • Stomach ulcers
      • Zollinger-Ellison syndrome (rare condition caused by a tumour in the pancreas or gut)

    Dosage and Strength

    • Available in 20mg and 40mg tablets, capsules, and granules
    • Typical dose:
      • Heartburn and acid reflux: 20mg a day
      • Gastro-oesophageal reflux disease: 20mg to 40mg a day
      • Stomach ulcers: 20mg a day
      • Zollinger-Ellison syndrome: 80mg a day (can increase to 160mg a day)

    How to Take

    • Take once a day, in the morning, with or without food
    • Swallow tablets and capsules whole with a drink of water
    • If taking granules, mix with water and drink straight away

    Common Side Effects

    • Headache
    • Diarrhoea
    • Stomach pain
    • Dizziness or sleepiness
    • Blurred vision

    Serious Side Effects

    • Liver problems (jaundice, dark urine, tiredness)
    • Joint pain with skin rash (subacute cutaneous lupus erythematosus)
    • Diarrhoea that does not improve
    • Serious allergic reaction (anaphylaxis)

    Long-term Side Effects

    • Low magnesium levels (tiredness, confusion, dizziness)
    • Bone fractures
    • Gut infections
    • Vitamin B12 deficiency

    Pregnancy and Breastfeeding

    • Limited information on use during pregnancy
    • Can be used while breastfeeding, but discuss with doctor or pharmacist first

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    Description

    Explore the uses and administration of esomeprazole, a medication that reduces stomach acid production, treating conditions like indigestion, heartburn, and gastro-oesophageal reflux disease.

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