Enzymes in Glycolysis and Gluconeogenesis Summary Quiz
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Questions and Answers

What is the primary energy source for the brain, skeletal muscle, and red blood cells?

  • Propionate
  • Glucose (correct)
  • Alanine
  • Glycerol
  • What is the purpose of gluconeogenesis in the liver and kidneys?

  • To synthesize glucose from non-carbohydrate precursors (correct)
  • To break down glucose into energy
  • To convert glucose into lactate
  • To store glucose in the form of glycogen
  • What are some examples of non-carbohydrate precursors used in gluconeogenesis?

  • Lactate, pyruvate, glucogenic amino acids, glycerol, and propionate (correct)
  • Alanine, aspartate, and glucose
  • Glycerol, propionate, and ketone bodies
  • Lactate, pyruvate, and glucose
  • Why is gluconeogenesis necessary during periods of starvation or fasting?

    <p>To provide energy to the brain and nervous system</p> Signup and view all the answers

    What is the estimated daily glucose requirement of the brain?

    <p>120 g/day</p> Signup and view all the answers

    What is the primary function of the Cori cycle?

    <p>To prevent lactate accumulation in muscles</p> Signup and view all the answers

    What is the byproduct of the breakdown of triacylglycerols in adipose tissue?

    <p>Glycerol and fatty acids</p> Signup and view all the answers

    What is the type of bond that creates branches in glycogen?

    <p>α-1,6-glycosidic bond</p> Signup and view all the answers

    What is the net energy cost of gluconeogenesis?

    <p>6 ATP molecules</p> Signup and view all the answers

    What happens to glucose after absorption in the well-fed state?

    <p>It is stored as glycogen in the liver</p> Signup and view all the answers

    What is the intermediate molecule in the conversion of glycerol to glucose?

    <p>Dihydroxyacetone phosphate (DHAP)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of oxaloacetate to PEP in the gluconeogenesis pathway?

    <p>Pyruvate carboxylase</p> Signup and view all the answers

    Which enzyme is responsible for converting fructose-1,6-bisphosphate to fructose-6-phosphate in the gluconeogenic pathway?

    <p>Fructose-1,6-bisphosphatase</p> Signup and view all the answers

    What are the non-carbohydrate precursors that can be converted to pyruvate and considered glucogenic?

    <p>Lactate and alanine</p> Signup and view all the answers

    Which of the following enzymes is NOT involved in the gluconeogenesis process?

    <p>Pyruvate kinase</p> Signup and view all the answers

    Which of the following statements about the energy cost of gluconeogenesis is true?

    <p>Overall, glucose synthesis in gluconeogenesis requires 4 ATP, 2 GTP, and 2 NADH.</p> Signup and view all the answers

    What enzyme catalyzes the conversion of glucose-6-phosphate to glucose in the liver and kidney?

    <p>Glucose-6-phosphatase</p> Signup and view all the answers

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