Endocrine Physiology PHGY 222 Quiz Objectives

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18 Questions

Insulin targets the ______, muscles, and adipose tissues

liver

Parathyroid hormone (PTH) regulates blood ______ level

calcium

Adrenal Medulla hormones stimulate the activities of their target ______

glands

Oxytocin targets the ______ and mammary glands

uterus

Melatonin regulates circadian rhythms in the ______

brain

Catecholamines assist in water and electrolyte balance and regulate blood ______ level

glucose

The pituitary gland is located in the ______

brain

The hormone secreted by the anterior pituitary that stimulates thyroid function is ______

TSH

The hormone secreted by the pancreas that lowers blood sugar levels is ______

insulin

The adrenal cortex secretes mineralocorticoids such as ______

aldosterone

The hormone secreted by the adrenal medulla that prepares the body for 'fight or flight' response is ______

adrenaline

The hormone secreted by the thyroid gland that regulates metabolism is ______

thyroxine

Gigantism is caused by oversecretion of ______ hormone during childhood

growth

Acromegaly is caused by excessive growth hormone secretion after ______

adolescence

Diabetes Mellitus is a syndrome caused by either lack of insulin secretion or decreased sensitivity of tissues to ______

insulin

Type I diabetes is also called insulin-dependent diabetes mellitus (IDDM) and is caused by lack of ______ secretion

insulin

Type II diabetes is also called non–insulin-dependent diabetes mellitus (NIDDM) and is caused by decreased sensitivity of target tissues to the metabolic effect of ______

insulin

Cushing’s disease is caused by hypersecretion of ______, due to primary tumor

cortisol

Study Notes

Endocrine Glands and Hormones

  • Endocrine glands: Pituitary gland, Thyroid gland, Parathyroid glands, Pancreas, Adrenal glands, Sex glands
  • Functions of endocrine glands: regulate growth and development, maintain homeostasis, respond to stress

Pituitary Gland

  • Anterior Pituitary: produces 6 hormones, regulates growth and development, stimulates other endocrine glands
  • Posterior Pituitary: produces 2 hormones, regulates water balance and uterine contraction
  • Hormones produced by Anterior Pituitary:
    • Growth Hormone Releasing Hormone (GHRH)
    • Thyroid-Releasing Hormone (TRH)
    • Corticotropin Releasing Hormone (CRH)
    • Gonadotropin Releasing Hormone (GnRH)
    • Prolactin Releasing Hormone (PRH)
    • Growth Hormone (GH)
    • Thyroid-Stimulating Hormone (TSH)
    • Adrenocorticotropic Hormone (ACTH)
    • Follicle-Stimulating Hormone (FSH)
  • Hormones produced by Posterior Pituitary:
    • Antidiuretic Hormone (ADH)
    • Oxytocin (OT)

Thyroid Gland

  • Produces 2 hormones:
    • Thyroxine (T4)
    • Triiodothyronine (T3)
    • Calcitonin

Parathyroid Gland

  • Produces 1 hormone:
    • Parathormone (PTH)

Pancreas

  • Produces 4 hormones:
    • Insulin
    • Glucagon
    • Somatostatin
    • Pancreatic Polypeptide

Adrenal Glands

  • Adrenal Cortex:
    • Produces 3 types of hormones:
      • Mineralocorticoids (Aldosterone)
      • Glucocorticoids (Cortisol, Corticosterone)
      • Sex Hormones (Androgens, Estrogen, Progesterone)
  • Adrenal Medulla:
    • Produces 3 hormones:
      • Catecholamines (Adrenaline/Noradrenaline, Dopamine)

Pathophysiology

  • Hyposecretion: underproduction of hormones
  • Hypersecretion: overproduction of hormones
  • Disorders of Pituitary Gland:
    • Panhypopituitarism: underproduction of all Anterior Pituitary hormones
    • Gigantism: oversecretion of Growth Hormone during childhood
    • Pituitary Dwarfism: underproduction of Growth Hormone during childhood
    • Acromegaly: oversecretion of Growth Hormone after adolescence
  • Disorders of Pancreas:
    • Diabetes Mellitus: impaired carbohydrate, fat, and protein metabolism
    • Type I Diabetes (IDDM): lack of insulin secretion
    • Type II Diabetes (NIDDM): decreased sensitivity of target tissues to insulin
  • Disorders of Adrenal Cortex:
    • Cushing's disease: hypersecretion of cortisol, leading to high blood glucose levels and lipid deposits
    • Addison's disease: hyposecretion of cortisol, leading to low blood glucose levels and low Na levels

Test your knowledge on the identification, location, structure, and functions of endocrine glands, as well as the regulation and control of hormone secretion. Topics include the pituitary gland, thyroid gland, parathyroid glands, pancreas, adrenal glands, and sex glands.

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