Endocrine Drugs and Contraception Therapy Quiz
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Questions and Answers

Which drug is recommended in most guidelines for adults with primary hypothyroidism?

  • Liothyronine
  • Levothyroxine (correct)
  • Propylthiouracil
  • Methimazole

    • What is the recommended timing for taking levothyroxine?

  • Before bedtime with a snack
  • At any time during the day
  • With a meal
  • 1st thing in the morning on an empty stomach (correct)

    • Which drug is to be avoided in the 1st trimester of pregnancy?

  • Levothyroxine
  • Propylthiouracil
  • Methimazole (correct)
  • Liothyronine

    • Which drug is used for certain thyroid cancers?

    <p>Radioactive iodine (Iodine-131)</p> Signup and view all the answers

    What is the Black Box Warning for levothyroxine?

    <p>Not for weight loss</p> Signup and view all the answers

    Which drug is more common than propylthiouracil?

    <p>Methimazole</p> Signup and view all the answers

    Which substances can affect levothyroxine absorption?

    <p>Bile acid sequestrants, calcium carbonate, GI meds</p> Signup and view all the answers

    What are the rare, serious adverse effects of thionamides used for hyperthyroidism treatment?

    <p>Agranulocytosis, hepatotoxicity, vasculitis</p> Signup and view all the answers

    Which drugs are considered antiresorptive therapies for osteoporosis?

    <p>Alendronate, risedronate, zoledronic acid, denosumab</p> Signup and view all the answers

    What is the mechanism of action of radioactive iodine in treating hyperthyroidism?

    <p>Damaging or destroying thyroid cells</p> Signup and view all the answers

    What are the reasons for dose increase of levothyroxine?

    <p>Pregnancy, weight gain, estrogen therapy</p> Signup and view all the answers

    What are the anabolic therapies for osteoporosis?

    <p>Teriparatide, abaloparatide, romosozumab</p> Signup and view all the answers

    What is the duration of use for Depo-Provera (DMPA) and Depo-SubQ?

    <p>Depo-Provera: 12 weeks, Depo-SubQ: 12 weeks</p> Signup and view all the answers

    When must progesterone be administered with estrogen in menopausal hormone therapy?

    <p>For women with a uterus, to counterbalance estrogen-mediated stimulation of the endometrium</p> Signup and view all the answers

    What are contraindications for oral and transdermal hormone therapy in menopause?

    <p>Personal or family history of breast cancer and/or cardiovascular disease</p> Signup and view all the answers

    What hormone therapy is scheduled/controlled?

    <p>All formulations of testosterone</p> Signup and view all the answers

    What are potential adverse effects of testosterone?

    <p>Fluid and sodium retention</p> Signup and view all the answers

    What baseline data should be collected for androgens?

    <p>Serum testosterone concentration, complete blood count (CBC), lipid panel, liver function, prostate specific antigen (PSA)</p> Signup and view all the answers

    What monitoring is recommended for androgens after 1 year?

    <p>Serum testosterone concentration, lipids, liver function, and PSA</p> Signup and view all the answers

    Who are contraindicated for androgen therapy?

    <p>Pregnant women, men with prostate cancer or breast cancer, and those using it for enhancing athletic performance</p> Signup and view all the answers

    Is levothyroxine the recommended thyroid therapy for adults with primary hypothyroidism?

    <p>True</p> Signup and view all the answers

    Is it acceptable to change between generic and name brand levothyroxine without consideration?

    <p>False</p> Signup and view all the answers

    Is the starting dose of levothyroxine the same for young, healthy patients and older patients with cardiovascular disease?

    <p>False</p> Signup and view all the answers

    Is liothyronine (Triostat) more common than propylthiouracil for treating hyperthyroidism?

    <p>True</p> Signup and view all the answers

    Is Radioactive iodine (Iodine-131) generally well tolerated for treating certain thyroid cancers?

    <p>True</p> Signup and view all the answers

    Is methimazole (Northyx) recommended for the 1st trimester of pregnancy?

    <p>False</p> Signup and view all the answers

    Levothyroxine dosing should be started high and titrated down with small dose decreases

    <p>False</p> Signup and view all the answers

    Radioactive iodine treats hyperthyroidism by stimulating thyroid cell growth

    <p>False</p> Signup and view all the answers

    Alendronate, risedronate, and zoledronic acid are anabolic therapies for osteoporosis

    <p>False</p> Signup and view all the answers

    Supplementation for osteoporosis treatment includes vitamin K

    <p>False</p> Signup and view all the answers

    Oral progestin-only contraceptives have no potential adverse effects

    <p>False</p> Signup and view all the answers

    DMPA administration requires no special considerations

    <p>False</p> Signup and view all the answers

    Depo-Provera and Depo-SubQ are examples of LARCs.

    <p>False</p> Signup and view all the answers

    The duration of use for Depo-Provera (DMPA) is greater than 2 years if other methods are inappropriate.

    <p>False</p> Signup and view all the answers

    Progesterone must be administered with estrogen in menopausal hormone therapy for women with uterus to prevent endometrial hyperplasia and cancer.

    <p>True</p> Signup and view all the answers

    Personal or family history of breast cancer and/or cardiovascular disease are contraindications for oral and transdermal hormone therapy in menopause.

    <p>True</p> Signup and view all the answers

    All formulations of testosterone are Schedule III Controlled Substances.

    <p>True</p> Signup and view all the answers

    Testosterone can increase HDL levels.

    <p>False</p> Signup and view all the answers

    The baseline data for androgens includes complete blood count (CBC), lipids, liver function, and prostate specific antigen (PSA).

    <p>True</p> Signup and view all the answers

    Androgens are contraindicated for pregnant women, men with prostate cancer or breast cancer, and those using it for enhancing athletic performance.

    <p>True</p> Signup and view all the answers

    Study Notes

    Endocrine Drugs and Contraception Therapy Study Guide

    • Levothyroxine dosing influenced by narrow therapeutic index, starting low and titrating with small dose increases
    • Reasons for dose increase of levothyroxine: pregnancy, weight gain, estrogen therapy
    • Substances affecting levothyroxine absorption: bile acid sequestrants, calcium carbonate, GI meds
    • Drugs treating hyperthyroidism symptoms: atenolol; treating condition: thionamides, radioactive iodine, surgery
    • Thionamides used for hyperthyroidism treatment
    • Rare, serious adverse effects of thionamides: agranulocytosis, hepatotoxicity, vasculitis
    • Radioactive iodine treats hyperthyroidism by damaging or destroying thyroid cells
    • Antiresorptive therapies for osteoporosis: alendronate, risedronate, zoledronic acid, denosumab
    • Anabolic therapies for osteoporosis: teriparatide, abaloparatide, romosozumab
    • Supplementation for osteoporosis treatment: calcium, vitamin D
    • Adverse effects and contraindications for oral and transdermal estrogens and progestins
    • Considerations for oral progestin-only contraceptives and DMPA administration, potential adverse effects

    Endocrine Drugs and Contraception Therapy Study Guide

    • Levothyroxine dosing influenced by narrow therapeutic index, starting low and titrating with small dose increases
    • Reasons for dose increase of levothyroxine: pregnancy, weight gain, estrogen therapy
    • Substances affecting levothyroxine absorption: bile acid sequestrants, calcium carbonate, GI meds
    • Drugs treating hyperthyroidism symptoms: atenolol; treating condition: thionamides, radioactive iodine, surgery
    • Thionamides used for hyperthyroidism treatment
    • Rare, serious adverse effects of thionamides: agranulocytosis, hepatotoxicity, vasculitis
    • Radioactive iodine treats hyperthyroidism by damaging or destroying thyroid cells
    • Antiresorptive therapies for osteoporosis: alendronate, risedronate, zoledronic acid, denosumab
    • Anabolic therapies for osteoporosis: teriparatide, abaloparatide, romosozumab
    • Supplementation for osteoporosis treatment: calcium, vitamin D
    • Adverse effects and contraindications for oral and transdermal estrogens and progestins
    • Considerations for oral progestin-only contraceptives and DMPA administration, potential adverse effects

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    Related Documents

    6024 M12 Study Guide - Endocrine Drugs PDF

    Description

    Test your knowledge of endocrine drugs and contraception therapy with this study guide. Learn about dosing, adverse effects, and treatment options for conditions such as hyperthyroidism and osteoporosis, as well as considerations for contraception and hormone therapy.

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