40 Questions
Which bacterium is known to cause syphilis?
Treponema Pallidium
What disease is caused by Borrelia recurrentis?
Leptospirosis
Which organism is responsible for causing relapsing fever?
Borrelia burgdorferi
Which bacterium is associated with the disease known as leptospirosis?
Vibrio cholerae
Which bacterium possesses flagella in bundles called axial filaments?
Borrelia burgdorferi
What is the major virulence factor of Haemophilus influenzae in respiratory infections?
Capsule
Which of the following infections is caused by Haemophilus ducreyi?
Chancroid
In which region of the USA are most cases of tularemia caused by Francisella tularensis reported?
Southeast
Which Gram-negative rod is fastidious in culture and requires special media for growth?
Legionella pneumophila
Which virulence factor is common among Gram-negative bacteria such as Pseudomonas aeruginosa, besides the capsule?
Enzymes
Which Gram-negative bacterium is known for causing hemolytic uremia syndrome and kidney damage in humans?
E.coli O157:H7
Which Gram-negative bacterium can be treated with antibiotics and is commonly found in soil and feces?
Enterobacter aerogenes
Which Gram-negative bacterium causes wound infections and pneumonia, with its capsule being a major virulence factor?
Klebsiella pneumoniae
Which Gram-negative bacterium is a common cause of urinary tract infections and produces urease?
Proteus sp
Which Gram-negative bacterium is associated with being common in cows, deer, and swine, and can cause diarrhea and kidney damage in humans?
E.coli O157:H7
Which bacterium is known for causing cholera?
Vibrio cholerae
What is a notable feature of spirochetes?
Flagellar motility
Which bacterium is associated with Lyme disease?
Borrelia burgdorferi
What is a common symptom associated with Campylobacter jejuni infection?
Arthritis
Which bacterium causes relapsing fever transmitted by lice?
Borrelia recurrentis
What is the most common cause of bacterial gastroenteritis?
Campylobacter jejuni
Which bacterium is known for causing ulcers and gastritis?
Helicobacter pylori
Which bacterium is known for being zoonotic and causing bacterial gastroenteritis?
Campylobacter jejuni
Which bacterium is associated with being the cause of stomach cancer?
Helicobacter pylori
Which bacterium has flagella and cytotoxin as part of its characteristics?
Vibrio cholerae
Which Gram-negative bacteria is known to cause cholera?
Vibrio cholerae
Which pathogen is responsible for causing a relapsing fever transmitted by lice?
Borrelia recurrentis
Which Gram-negative bacterium is associated with causing Lyme disease?
Borrelia burgdorferi
Which of the following is a Gram-negative bacterium that can cause gastroenteritis in humans?
Vibrio cholerae
Which of the following bacteria is commonly associated with foodborne illnesses?
Campylobacter jejuni
What is the main symptom of food poisoning caused by a large dose of a certain pathogen present on eggs and poultry?
Diarrhea
Which pathogen is associated with typhoid fever and spreads through the body, with the gall bladder acting as a reservoir?
Vibrio cholerae
How is Shigella mainly transmitted to cause infections in humans?
By direct cell-to-cell contact
Which pathogen produces a toxin that inhibits protein synthesis, leading to increased damage in infected individuals?
Campylobacter jejuni
What is the most serious consequence of diarrheal diseases like shigellosis caused by S.dysenteriae?
Dehydration
Which pathogen is commonly associated with causing symptoms such as cramps, diarrhea, and bloody stools due to infection of the intestinal lining?
Campylobacter jejuni
What type of toxin does S.dysenteriae produce that contributes to its virulence?
Exotoxin
Which preventative measure is particularly emphasized in controlling infections caused by Shigella sp.?
Good personal hygiene
What makes Vibrio cholerae a significant public health concern?
The rapid dehydration it causes
What distinguishes Yersinia sp. as a pathogenic enteric organism?
Its association with foodborne illness
Study Notes
Gram Negative Bacteria
- Legionella pneumophila and other species are fastidious in culture, requiring special media, and are commonly found in aquatic environments such as ponds, cooling towers, hot-water heaters, and showers.
Pseudomonas
- Pseudomonas aeruginosa is a very common bacterium in the environment, especially in soil, and is an opportunistic pathogen.
- It produces endotoxin, exotoxins, fimbriae, and enzymes, and has a capsule as a major virulence factor.
- It is capable of causing disease anywhere in the body and is a major problem in burn patients and those with cystic fibrosis.
- It is resistant to most disinfectants and antibiotics.
Leptospira
- Leptospira sp. is transmitted by both wild and domestic animals, with rodents being the most common animals spreading the disease.
- The bacterium is transmitted through animal urine or water contaminated with animal urine coming into contact with breaks in the skin, eyes, mouth, nose, or vagina.
- Leptospirosis is a two-phase disease that begins with flu-like symptoms and can progress to liver damage, renal failure, meningitis, and encephalitis.
Spirochetes
- Spirochetes are characterized by internal flagella in bundles called axial filaments, which twist through liquid media.
- Treponema pallidum is the cause of syphilis, a sexually transmitted infection.
- H. ducreyi is a sexually transmitted infection that causes chancroid, a visible and painful infection in men.
Francisella
- Francisella tularensis is the cause of tularemia, also known as rabbit fever, tick fever, or deerfly fever.
- It survives phagocytosis and lives intracellularly, and is present in many animals, including rabbits, deer, and rodents.
- Transmission occurs through vectors, ingestion, direct contact, or inhalation, and symptoms include chills, fever, malaise, and swollen nodes.
Legionella
- Legionella pneumophila is a fastidious bacterium that requires special media to grow and is commonly found in aquatic environments.
- It is an opportunistic pathogen that can cause pneumonia, especially in people with compromised immune systems.
Bacteroides
- Bacteroides sp. is a common anaerobic bacterium found in the GI tract and other parts of the body.
- It is an opportunistic pathogen that can cause abscesses in the GI tract, reproductive tract, and wounds.
Other Gram Negative Rods
- Klebsiella pneumoniae is an opportunistic pathogen that can cause wound infections, pneumonia, and other infections.
- Proteus sp. is a common cause of urinary tract infections and can change shape and flagella between liquid and solid media.
- Enterobacter aerogenes is a coliform bacterium that can cause wound infections and is found in the GI tract and environment.
Enterobacteriaceae
- Enterobacteriaceae are a family of Gram-negative rods that are facultatively anaerobic and are found in soil, water, and the GI tract.
- They are generally divided into coliforms (ferment lactose) and non-coliforms, and can be identified using biochemical tests, selective/differential media, and serological techniques.
Campylobacter
- Campylobacter jejuni is a curved rod that causes bacterial gastroenteritis, especially through contaminated chicken and milk.
- It has flagella and chemotaxis, and a low infectious dose.
Helicobacter
- Helicobacter pylori is a curved rod that causes ulcers and gastritis, and was discovered by Barry Marshall and J. Robin Warren, who won the Nobel Prize in Medicine in 2005.
- It produces urease, which neutralizes stomach acid and irritates the stomach lining, and has flagella and a cytotoxin.
Explore the pathogenicity of E.coli O157:H7, a specific serotype known for producing dangerous exotoxin, causing diseases like diarrhea and urinary tract infections. Learn about its virulence factors and the role of Shiga toxin in inhibiting protein synthesis.
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