E.coli O157:H7 and its Pathogenicity
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Questions and Answers

Which bacterium is known to cause syphilis?

  • vibrio cholera
  • Borrelia burgdorferi
  • Campylobacter jejuni
  • Treponema Pallidium (correct)
  • What disease is caused by Borrelia recurrentis?

  • Relapsing fever
  • Pontiac fever
  • Leptospirosis (correct)
  • Syphilis
  • Which organism is responsible for causing relapsing fever?

  • Vibrio cholerae
  • Campylobacter jejuni
  • Borrelia burgdorferi (correct)
  • Borrelia recurrentis
  • Which bacterium is associated with the disease known as leptospirosis?

    <p>Vibrio cholerae</p> Signup and view all the answers

    Which bacterium possesses flagella in bundles called axial filaments?

    <p>Borrelia burgdorferi</p> Signup and view all the answers

    What is the major virulence factor of Haemophilus influenzae in respiratory infections?

    <p>Capsule</p> Signup and view all the answers

    Which of the following infections is caused by Haemophilus ducreyi?

    <p>Chancroid</p> Signup and view all the answers

    In which region of the USA are most cases of tularemia caused by Francisella tularensis reported?

    <p>Southeast</p> Signup and view all the answers

    Which Gram-negative rod is fastidious in culture and requires special media for growth?

    <p>Legionella pneumophila</p> Signup and view all the answers

    Which virulence factor is common among Gram-negative bacteria such as Pseudomonas aeruginosa, besides the capsule?

    <p>Enzymes</p> Signup and view all the answers

    Which Gram-negative bacterium is known for causing hemolytic uremia syndrome and kidney damage in humans?

    <p>E.coli O157:H7</p> Signup and view all the answers

    Which Gram-negative bacterium can be treated with antibiotics and is commonly found in soil and feces?

    <p>Enterobacter aerogenes</p> Signup and view all the answers

    Which Gram-negative bacterium causes wound infections and pneumonia, with its capsule being a major virulence factor?

    <p>Klebsiella pneumoniae</p> Signup and view all the answers

    Which Gram-negative bacterium is a common cause of urinary tract infections and produces urease?

    <p>Proteus sp</p> Signup and view all the answers

    Which Gram-negative bacterium is associated with being common in cows, deer, and swine, and can cause diarrhea and kidney damage in humans?

    <p>E.coli O157:H7</p> Signup and view all the answers

    Which bacterium is known for causing cholera?

    <p>Vibrio cholerae</p> Signup and view all the answers

    What is a notable feature of spirochetes?

    <p>Flagellar motility</p> Signup and view all the answers

    Which bacterium is associated with Lyme disease?

    <p>Borrelia burgdorferi</p> Signup and view all the answers

    What is a common symptom associated with Campylobacter jejuni infection?

    <p>Arthritis</p> Signup and view all the answers

    Which bacterium causes relapsing fever transmitted by lice?

    <p>Borrelia recurrentis</p> Signup and view all the answers

    What is the most common cause of bacterial gastroenteritis?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    Which bacterium is known for causing ulcers and gastritis?

    <p>Helicobacter pylori</p> Signup and view all the answers

    Which bacterium is known for being zoonotic and causing bacterial gastroenteritis?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    Which bacterium is associated with being the cause of stomach cancer?

    <p>Helicobacter pylori</p> Signup and view all the answers

    Which bacterium has flagella and cytotoxin as part of its characteristics?

    <p>Vibrio cholerae</p> Signup and view all the answers

    Which Gram-negative bacteria is known to cause cholera?

    <p>Vibrio cholerae</p> Signup and view all the answers

    Which pathogen is responsible for causing a relapsing fever transmitted by lice?

    <p>Borrelia recurrentis</p> Signup and view all the answers

    Which Gram-negative bacterium is associated with causing Lyme disease?

    <p>Borrelia burgdorferi</p> Signup and view all the answers

    Which of the following is a Gram-negative bacterium that can cause gastroenteritis in humans?

    <p>Vibrio cholerae</p> Signup and view all the answers

    Which of the following bacteria is commonly associated with foodborne illnesses?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    What is the main symptom of food poisoning caused by a large dose of a certain pathogen present on eggs and poultry?

    <p>Diarrhea</p> Signup and view all the answers

    Which pathogen is associated with typhoid fever and spreads through the body, with the gall bladder acting as a reservoir?

    <p>Vibrio cholerae</p> Signup and view all the answers

    How is Shigella mainly transmitted to cause infections in humans?

    <p>By direct cell-to-cell contact</p> Signup and view all the answers

    Which pathogen produces a toxin that inhibits protein synthesis, leading to increased damage in infected individuals?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    What is the most serious consequence of diarrheal diseases like shigellosis caused by S.dysenteriae?

    <p>Dehydration</p> Signup and view all the answers

    Which pathogen is commonly associated with causing symptoms such as cramps, diarrhea, and bloody stools due to infection of the intestinal lining?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    What type of toxin does S.dysenteriae produce that contributes to its virulence?

    <p>Exotoxin</p> Signup and view all the answers

    Which preventative measure is particularly emphasized in controlling infections caused by Shigella sp.?

    <p>Good personal hygiene</p> Signup and view all the answers

    What makes Vibrio cholerae a significant public health concern?

    <p>The rapid dehydration it causes</p> Signup and view all the answers

    What distinguishes Yersinia sp. as a pathogenic enteric organism?

    <p>Its association with foodborne illness</p> Signup and view all the answers

    Study Notes

    Gram Negative Bacteria

    • Legionella pneumophila and other species are fastidious in culture, requiring special media, and are commonly found in aquatic environments such as ponds, cooling towers, hot-water heaters, and showers.

    Pseudomonas

    • Pseudomonas aeruginosa is a very common bacterium in the environment, especially in soil, and is an opportunistic pathogen.
    • It produces endotoxin, exotoxins, fimbriae, and enzymes, and has a capsule as a major virulence factor.
    • It is capable of causing disease anywhere in the body and is a major problem in burn patients and those with cystic fibrosis.
    • It is resistant to most disinfectants and antibiotics.

    Leptospira

    • Leptospira sp. is transmitted by both wild and domestic animals, with rodents being the most common animals spreading the disease.
    • The bacterium is transmitted through animal urine or water contaminated with animal urine coming into contact with breaks in the skin, eyes, mouth, nose, or vagina.
    • Leptospirosis is a two-phase disease that begins with flu-like symptoms and can progress to liver damage, renal failure, meningitis, and encephalitis.

    Spirochetes

    • Spirochetes are characterized by internal flagella in bundles called axial filaments, which twist through liquid media.
    • Treponema pallidum is the cause of syphilis, a sexually transmitted infection.
    • H. ducreyi is a sexually transmitted infection that causes chancroid, a visible and painful infection in men.

    Francisella

    • Francisella tularensis is the cause of tularemia, also known as rabbit fever, tick fever, or deerfly fever.
    • It survives phagocytosis and lives intracellularly, and is present in many animals, including rabbits, deer, and rodents.
    • Transmission occurs through vectors, ingestion, direct contact, or inhalation, and symptoms include chills, fever, malaise, and swollen nodes.

    Legionella

    • Legionella pneumophila is a fastidious bacterium that requires special media to grow and is commonly found in aquatic environments.
    • It is an opportunistic pathogen that can cause pneumonia, especially in people with compromised immune systems.

    Bacteroides

    • Bacteroides sp. is a common anaerobic bacterium found in the GI tract and other parts of the body.
    • It is an opportunistic pathogen that can cause abscesses in the GI tract, reproductive tract, and wounds.

    Other Gram Negative Rods

    • Klebsiella pneumoniae is an opportunistic pathogen that can cause wound infections, pneumonia, and other infections.
    • Proteus sp. is a common cause of urinary tract infections and can change shape and flagella between liquid and solid media.
    • Enterobacter aerogenes is a coliform bacterium that can cause wound infections and is found in the GI tract and environment.

    Enterobacteriaceae

    • Enterobacteriaceae are a family of Gram-negative rods that are facultatively anaerobic and are found in soil, water, and the GI tract.
    • They are generally divided into coliforms (ferment lactose) and non-coliforms, and can be identified using biochemical tests, selective/differential media, and serological techniques.

    Campylobacter

    • Campylobacter jejuni is a curved rod that causes bacterial gastroenteritis, especially through contaminated chicken and milk.
    • It has flagella and chemotaxis, and a low infectious dose.

    Helicobacter

    • Helicobacter pylori is a curved rod that causes ulcers and gastritis, and was discovered by Barry Marshall and J. Robin Warren, who won the Nobel Prize in Medicine in 2005.
    • It produces urease, which neutralizes stomach acid and irritates the stomach lining, and has flagella and a cytotoxin.

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    Description

    Explore the pathogenicity of E.coli O157:H7, a specific serotype known for producing dangerous exotoxin, causing diseases like diarrhea and urinary tract infections. Learn about its virulence factors and the role of Shiga toxin in inhibiting protein synthesis.

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