Eating Disorders Overview and Clinical Features
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Questions and Answers

What is a clinical manifestation specifically associated with Anorexia Nervosa?

  • Swollen salivary glands
  • Amenorrhea (correct)
  • Pitted teeth
  • Obesity
  • Which risk factor is primarily linked to Bulimia Nervosa?

  • Impulsivity (correct)
  • Chronic dieting
  • Emotional eating
  • Perfectionism
  • What is a significant difference between Binge Eating Disorder and Bulimia Nervosa?

  • Binge Eating Disorder involves compensatory behaviors.
  • Bulimia Nervosa leads to systemic inflammation.
  • Binge Eating Disorder is associated with obesity. (correct)
  • Bulimia Nervosa has no episodes of eating control.
  • What pathophysiological change is primarily observed in Anorexia Nervosa?

    <p>HPA axis dysfunction (C)</p> Signup and view all the answers

    Which of the following clinical manifestations is associated with Bulimia Nervosa?

    <p>Electrolyte imbalances (D)</p> Signup and view all the answers

    Which risk factor is NOT associated with Anorexia Nervosa?

    <p>Impulsivity (C)</p> Signup and view all the answers

    What pathophysiological mechanism is specifically linked to Anorexia Nervosa?

    <p>Low serotonin activity (B)</p> Signup and view all the answers

    Which psychological factor is associated with Binge Eating Disorder?

    <p>Emotional eating (C)</p> Signup and view all the answers

    What clinical manifestation is commonly seen in Bulimia Nervosa?

    <p>Binge-purge cycles (A)</p> Signup and view all the answers

    Which statement accurately describes the HPA axis in those with Bulimia Nervosa?

    <p>It activates during stress and emotional eating. (A)</p> Signup and view all the answers

    Which risk factor is a commonality between all three eating disorders?

    <p>Family history of eating disorders (B)</p> Signup and view all the answers

    What neurotransmitter imbalance is specifically associated with Bulimia Nervosa?

    <p>Dopamine dysregulation (A)</p> Signup and view all the answers

    Which factor is linked to the pathophysiological mechanism of Binge Eating Disorder?

    <p>Low inhibitory control of food intake (D)</p> Signup and view all the answers

    Flashcards

    Anorexia Nervosa

    An eating disorder characterized by extreme weight loss and fear of gaining weight.

    Clinical Manifestations of Anorexia

    Symptoms include underweight, amenorrhea, fatigue, and bradycardia.

    Bulimia Nervosa

    An eating disorder involving binge eating followed by purging behaviors.

    Binge Eating Disorder

    Characterized by recurrent episodes of excessive eating without compensatory behaviors.

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    Pathophysiology of Eating Disorders

    Involves hormonal and neurotransmitter dysfunction (e.g. serotonin and dopamine imbalances).

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    Anorexia Nervosa Risk Factors

    Genetic predisposition, perfectionism, societal pressure, and early onset.

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    Bulimia Nervosa Risk Factors

    Family history of eating disorders, impulsivity, trauma, and societal dieting pressure.

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    Binge Eating Disorder Risk Factors

    Family history of obesity, emotional eating, stress coping, and depression.

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    Anorexia Pathophysiology

    Involves hypothalamic dysfunction, increased cortisol, neurotransmitter imbalances.

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    Bulimia Pathophysiology

    Characterized by serotonin and dopamine dysregulation, electrolyte imbalances, and HPA axis activation.

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    Binge Eating Disorder Pathophysiology

    Involves dysregulated dopamine signaling, low inhibitory control, and hypothalamic dysfunction.

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    Risk factors of Anorexia

    Psychological factors include perfectionism and low self-esteem alongside genetic factors.

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    Dopamine Signaling

    This signaling affects the brain’s reward system and is implicated in eating disorders.

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    Study Notes

    Eating Disorders: Risk Factors, Pathophysiology, and Clinical Manifestations

    • Anorexia Nervosa (AN):

      • Risk Factors: Genetic predisposition, family history of eating disorders or mood disorders, perfectionism, low self-esteem, body dissatisfaction, societal pressure, stressful life events. Typically begins during adolescence or young adulthood.
      • Pathophysiology: Hypothalamic-pituitary axis dysfunction, leading to low gonadotropin-releasing hormone, reduced estrogen/testosterone, increased cortisol, neurotransmitter imbalances (low serotonin), and CNS neuropeptide dysregulation (altered neuropeptide-Y and leptin).
      • Clinical Manifestations: Extreme weight loss (BMI < 18.5), fear of gaining weight, distorted body image, amenorrhea, fatigue, bradycardia, low blood pressure, and osteopenia/osteoporosis.
    • Bulimia Nervosa (BN):

      • Risk Factors: Family history of eating disorders or substance abuse, impulsivity, emotional dysregulation, sociocultural influences, history of trauma or abuse.
      • Pathophysiology: Serotonin imbalance, dopamine dysregulation (altering reward processing), hypothalamic-pituitary-adrenal (HPA) axis activation related to stress and emotional eating, and electrolyte imbalances (sodium and potassium depletion from vomiting and laxative use).
      • Clinical Manifestations: Normal or slightly overweight body mass, recurrent episodes of binge eating, followed by compensatory behaviors (purging, laxatives, excessive exercise), pitted teeth, esophageal inflammation, swollen salivary glands, electrolyte imbalances (hypokalemia), and irregular heart rhythms.
    • Binge Eating Disorder (BED):

      • Risk Factors: Family history of obesity or eating disorders, emotional eating, low self-esteem, stress coping mechanisms, access to high-calorie foods, chronic dieting, and comorbid psychiatric conditions (depression or anxiety).
      • Pathophysiology: Dysregulated dopamine signaling, low inhibitory control of food intake, hypothalamic dysfunction, and neuroinflammation.
      • Clinical Manifestations: Recurrent episodes of consuming large amounts of food in short time frames, with a lack of control during episodes. No compensatory behaviors. Associated with obesity, type 2 diabetes, hypertension, cardiovascular risks, emotional distress, guilt, and shame after eating episodes.

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    Description

    This quiz covers the critical aspects of eating disorders, specifically Anorexia Nervosa and Bulimia Nervosa. Understand the risk factors, pathophysiological mechanisms, and clinical manifestations of these disorders. Test your knowledge on the complexities surrounding these serious mental health issues.

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