Podcast
Questions and Answers
What is the primary consequence of a disturbance in glucose action in Diabetes Mellitus?
What is the primary consequence of a disturbance in glucose action in Diabetes Mellitus?
- Hyperglycemia (correct)
- Polyuria
- Polydipsia
- Glycosuria
Which of the following is NOT a mechanism of action of insulin?
Which of the following is NOT a mechanism of action of insulin?
- Signal transmission to inside of cell
- Activation of catabolic pathways (correct)
- Inhibition of anabolic pathways
- Autophosphorylation of beta subunits
What is the primary reason insulin is not effective orally?
What is the primary reason insulin is not effective orally?
- Rapid onset of action and short duration
- Metabolized in liver and other tissues
- Rapidly inactivated by proteolytic enzymes (correct)
- Administered subcutaneously
What is the effect of insulin on protein metabolism?
What is the effect of insulin on protein metabolism?
What is the primary consequence of increased lipolysis in Diabetes Mellitus?
What is the primary consequence of increased lipolysis in Diabetes Mellitus?
What is the primary effect of insulin on fat metabolism?
What is the primary effect of insulin on fat metabolism?
What is the primary function of the Islets of Langerhans within the pancreas?
What is the primary function of the Islets of Langerhans within the pancreas?
What is the term for the condition characterized by impaired carbohydrate, protein, and fat metabolism due to insufficient insulin secretion or decreased response of target tissues to insulin?
What is the term for the condition characterized by impaired carbohydrate, protein, and fat metabolism due to insufficient insulin secretion or decreased response of target tissues to insulin?
What is the location of the pancreas in the body?
What is the location of the pancreas in the body?
What are the three major cell types that compose the Islets of Langerhans?
What are the three major cell types that compose the Islets of Langerhans?
What is the primary objective of the session on drugs for endocrine disorders?
What is the primary objective of the session on drugs for endocrine disorders?
What is a potential consequence of progressive loss of β cells in patients treated with Glibenclamide?
What is a potential consequence of progressive loss of β cells in patients treated with Glibenclamide?
What is the primary mechanism of action of Glibenclamide in promoting insulin secretion?
What is the primary mechanism of action of Glibenclamide in promoting insulin secretion?
What is a common adverse effect of Glibenclamide that is related to its insulin-like activity?
What is a common adverse effect of Glibenclamide that is related to its insulin-like activity?
What is the main organ responsible for the metabolism of Glibenclamide?
What is the main organ responsible for the metabolism of Glibenclamide?
What is the main difference between the mechanisms of action of Glibenclamide and Metformin?
What is the main difference between the mechanisms of action of Glibenclamide and Metformin?
What is the primary mechanism of metformin in reducing plasma glucose levels?
What is the primary mechanism of metformin in reducing plasma glucose levels?
What is the primary regulator of thyroid hormone secretion?
What is the primary regulator of thyroid hormone secretion?
What is the effect of thyroid hormones on protein synthesis?
What is the effect of thyroid hormones on protein synthesis?
What is the clinical use of metformin in combination with?
What is the clinical use of metformin in combination with?
What is the effect of metformin on glucose absorption from the GI tract?
What is the effect of metformin on glucose absorption from the GI tract?
What is the treatment for hypothyroidism?
What is the treatment for hypothyroidism?
What is the primary mechanism of action of levothyroxine in the nucleus?
What is the primary mechanism of action of levothyroxine in the nucleus?
What is the primary effect of high doses of levothyroxine on the cardiovascular system?
What is the primary effect of high doses of levothyroxine on the cardiovascular system?
What is the primary reason for administering levothyroxine on an empty stomach?
What is the primary reason for administering levothyroxine on an empty stomach?
What is the primary effect of hypothyroidism on the skin?
What is the primary effect of hypothyroidism on the skin?
What is the primary effect of hypothyroidism on the digestive system?
What is the primary effect of hypothyroidism on the digestive system?