10 Questions
What are some advantages associated with DDSs decorated through bio-stealth?
Improving specific interactions with the environment, enhancing particular targeting, biocompatibility, prolonged circulation time, and preferential accumulation in the TME
Which immune cells have been exploited as membrane sources to develop biohybrid stealth systems?
Macrophages, T cells, and red blood cells (RBC)
What is the significance of RBCs in nanosystems?
Enhanced targeting ability and circulation time
What is the approximate half-life of RBCs?
About 120 days
What are some advantages of using RBCs in drug delivery systems?
Good biocompatibility, immune recognition evasion, and low 2.3
What is the purpose of hydrogel-based long-acting drug delivery systems?
Local anticancer treatment in tumor resection cavities
What is the tumor resection cavity?
A space with the potential to house local anticancer therapeutics
Why are hydrogels extensively proposed for local anticancer treatment?
As water-retaining polymeric networks that can serve as drug reservoirs
What is the most frequently used treatment for solid tumors?
Tumor surgical resection
How can local anticancer therapeutics help post-surgery patients?
Prevent disease recurrence
Test your knowledge on drug release mechanisms and long-acting immunotherapy, including recent advances in polymeric conjugates. Explore concepts such as premature drug release, sustained drug delivery, and the usage of PD-L1 antibody blockers in immunotherapy.
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