Swellable Elementary Osmotic Pump (SEOP) System for Drug Release Study
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Questions and Answers

What type of regression analysis was used to reveal the optimum concentration of osmotic agent and size of delivery orifice?

Multiple linear regression

What type of plots were constructed to show the effects of X1 and X2 on %CDR?

Contour plots and response surface plots

What was the concentration of independent variables X1 and X2 predicted by the computer optimization process?

78.38 mg and 0.99 mm, respectively

How did the drug release from the developed formulation vary with pH and agitational intensity?

<p>It was found to be independent of pH and agitational intensity.</p> Signup and view all the answers

What was the duration of the stability study conducted for the optimized batch?

<p>6 months</p> Signup and view all the answers

What type of pharmacokinetic models were used to evaluate the optimized batch?

<p>Zero-order, first-order, Higuchi, Korsmeyer Peppas, and Hixson Crowell models</p> Signup and view all the answers

What is the potential application of osmotic tablets of Flurbiprofen?

<p>Treatment of rheumatoid arthritis and osteoarthritis</p> Signup and view all the answers

What type of pump was designed for efficient delivery of poorly water-soluble drugs?

<p>Elementary osmotic pump</p> Signup and view all the answers

What was the focus of the study by Preeti PANDEY and Saurabh PANDEY (2013)?

<p>Delivery of poorly water soluble drug from swellable elementary osmotic pump and effect of formulation variables</p> Signup and view all the answers

What was the effect of composition factors on the elementary osmotic pump tablet?

<p>The study investigated the effect of composition factors on the tablet.</p> Signup and view all the answers

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