DNA Structure: Nucleotides, Bases, and Double Helix
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Questions and Answers

Which molecular interaction is primarily responsible for maintaining the double helix structure of DNA?

  • Ionic bonds between the phosphate groups
  • Covalent bonds between the phosphate groups and nitrogenous bases
  • Hydrophobic interactions between the deoxyribose sugars
  • Hydrogen bonds between complementary nitrogenous bases (correct)

If a single strand of DNA has the sequence 5'-GATTACA-3', what would be the sequence of its complementary strand?

  • 3'-CTAATGT-5' (correct)
  • 5'-CTAATGT-3'
  • 3'-GATTACA-5'
  • 5'-TGTAATC-3'

What type of bond connects the deoxyribose sugar of one nucleotide to the phosphate group of the next, forming the backbone of a DNA strand?

  • Covalent bond (correct)
  • Hydrophobic interaction
  • Ionic bond
  • Hydrogen bond

A researcher isolates a nucleic acid and determines that it contains deoxyribose, a phosphate group, and thymine. Which of the following is the most likely identity of this molecule?

<p>Deoxyribonucleic acid (DNA) (A)</p> Signup and view all the answers

Which of the following is NOT a component of a DNA nucleotide?

<p>Ribose (A)</p> Signup and view all the answers

Flashcards

DNA Nucleotide

A building block of DNA, consisting of a 5-carbon sugar (deoxyribose), a phosphate group, and a nitrogenous base.

DNA Nitrogenous Bases

Adenine (A), Guanine (G), Cytosine (C), and Thymine (T).

Sugar-Phosphate Backbone

The backbone is formed by covalent bonds between the deoxyribose sugar of one nucleotide and the phosphate group of the next.

Antiparallel Strands

DNA strands run in opposite directions; one strand runs 5' to 3', the other 3' to 5'.

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Complementary Base Pairing

Adenine (A) pairs with Thymine (T), and Cytosine (C) pairs with Guanine (G).

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Study Notes

  • DNA nucleotide includes a 3-carbon sugar (deoxyribose), a phosphate group, and a nitrogenous base.
  • Four nitrogenous bases are in DNA nucleotides: A, G, C, and T.
  • Nucleotides are joined together by covalent bonds.
  • Covalent bonds form between the deoxyribose sugar of one nucleotide and the phosphate group of the next.
  • Each nucleotide in a DNA strand has a phosphate group (P), a deoxyribose sugar, and a nitrogenous base.
  • The phosphate of one nucleotide is covalently bonded to the next sugar, forming a sugar-phosphate backbone.
  • DNA double helix has 3 primary features including antiparallel strands.
  • At one end of an antiparallel strand, the phosphate group is located at the first nucleotide in the chain.
  • At the other end, the deoxyribose sugar of the last nucleotide is located in the chain.
  • The 2 strands in a double helix are joined by hydrogen bonds between the nitrogenous bases of nucleotides on opposite strands.
  • T pairs exclusively with A and C pairs exclusively with G during complementary base pairing.

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Description

Explore the structure of DNA, including its nucleotide composition with deoxyribose, phosphate groups, and nitrogenous bases (A, G, C, T). Understand how covalent bonds link nucleotides, forming a sugar-phosphate backbone. Learn about the antiparallel arrangement and hydrogen bonds in the DNA double helix.

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