Podcast
Questions and Answers
What statistical technique was used to calculate odds ratios?
What statistical technique was used to calculate odds ratios?
Logistic regression
Which covariates were selected as potential predictors of PDE?
Which covariates were selected as potential predictors of PDE?
Birth year, years of education, childhood sexual abuse, neuroticism, history of MD before the past year, introversion, self-esteem, social support, difficulties, and parental warmth
What approach was used to compare propensity matching?
What approach was used to compare propensity matching?
Co-twin control approach
What type of twin pairs were analyzed to obtain discordant pairs for risk factor exposure?
What type of twin pairs were analyzed to obtain discordant pairs for risk factor exposure?
What was used to create matched pairs discordant for exposure?
What was used to create matched pairs discordant for exposure?
Which episode reports were used as risk factors and which as outcomes?
Which episode reports were used as risk factors and which as outcomes?
What is the purpose of using a natural experiment in the study design?
What is the purpose of using a natural experiment in the study design?
How does the co-twin control method help in studying causality?
How does the co-twin control method help in studying causality?
What is the purpose of using propensity analysis in the study?
What is the purpose of using propensity analysis in the study?
How does the co-twin control method account for shared covariates?
How does the co-twin control method account for shared covariates?
What does propensity analysis do to ensure valid comparison between exposed and unexposed individuals?
What does propensity analysis do to ensure valid comparison between exposed and unexposed individuals?
How were the statistical methods (co-twin control and propensity analysis) applied in the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders?
How were the statistical methods (co-twin control and propensity analysis) applied in the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders?
What are the two approaches to evaluate causal processes when randomized controlled trials are not feasible for psychiatric disorders?
What are the two approaches to evaluate causal processes when randomized controlled trials are not feasible for psychiatric disorders?
According to counterfactual/interventionist theories of causation, what will happen to disease rates if the association between risk factors and major depression is causal?
According to counterfactual/interventionist theories of causation, what will happen to disease rates if the association between risk factors and major depression is causal?
What is the critical question regarding the association between dependent stressful life events (dSLEs), prior depressive episodes (PDEs), and major depression (MD)?
What is the critical question regarding the association between dependent stressful life events (dSLEs), prior depressive episodes (PDEs), and major depression (MD)?
What are some shared covariates that may predispose individuals to both dSLEs and MD?
What are some shared covariates that may predispose individuals to both dSLEs and MD?
What are some long-lasting risk factors for major depression, as mentioned in the text?
What are some long-lasting risk factors for major depression, as mentioned in the text?
Why are randomized controlled trials not feasible for many psychiatric disorders?
Why are randomized controlled trials not feasible for many psychiatric disorders?