Dentistry: Dentine and Dentine Hypersensitivity

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What is a mechanism by which odontoblasts may contribute to dental hypersensitivity?

Participating in the hydrodynamic mechanism of pain

Acting as a physical barrier to prevent fluid movement

Directly stimulating A-fibers to induce pain

Acting as receptor cells to relay impulses to nerve terminals (correct)

In the context of dental hypersensitivity, what occurs when a tooth is exposed to cold temperatures?

The dentinal tubules constrict, blocking the transmission of pain

Fluid flow is unaffected, and no pain is produced

Fluid expansion causes slow inward movement, producing a lingering pain

Fluid contraction causes accelerated outward movement, producing a sharp pain (correct)

Which of the following is a type of transmembrane receptor?

A-fibers

Adhesion molecules

Ion pumps

G-protein-coupled receptors (correct)

What is a common characteristic of dentinal tubules in teeth with hypersensitivity?

They are more abundant and have a greater diameter Signup and view all the answers

What is the mechanism by which high osmotic pressure stimulates pain?

Salty/sweet solutions draw water outwards, producing outward movement of fluid Signup and view all the answers

What is a limitation of the odontoblast transducer mechanism of dental hypersensitivity?

The evidence is patchy, and it is unclear if odontoblasts can be excited Signup and view all the answers

What is a characteristic of the hydrodynamic theory of dental hypersensitivity?

It suggests that fluid movement in the dentinal tubules produces a pain sensation Signup and view all the answers

What is a type of receptor that can be involved in dental hypersensitivity?

All of the above Signup and view all the answers

What percentage of mineral content is found in enamel?

96% Signup and view all the answers

What is the primary function of dentine tubules?

To make dentine spongy Signup and view all the answers

What is the relationship between water content, organic content, and mineral content in the hard tissues of the oral cavity?

Mineral content decreases with water content Signup and view all the answers

What type of dentine has the highest elastic modulus?

Tertiary Signup and view all the answers

What is the hardness range of dentine in GPa?

0.41-0.89 Signup and view all the answers

Which of the following is a characteristic of dentine?

It is porous Signup and view all the answers

What percentage of organic content is found in bone?

40% Signup and view all the answers

What is the main difference between primary, secondary, and tertiary dentine?

Their mineral content Signup and view all the answers

What is the purpose of not brushing teeth immediately after consuming acidic substances?

To prevent further dentine loss Signup and view all the answers

What is the role of fluoride in preventing tooth erosion?

To strengthen tooth enamel Signup and view all the answers

What is the purpose of using cheese, milk, or chewing gum?

To promote smear layer formation Signup and view all the answers

What is the purpose of sealing or restoring teeth?

To prevent further dentine loss Signup and view all the answers

What is the purpose of using toothpastes and mouthwashes with chemical components?

To strengthen tooth enamel Signup and view all the answers

What is the common property of transmembrane receptors, enzyme-linked receptors, and ion channels?

Responding to extracellular signals by inducing intracellular response Signup and view all the answers

What is the purpose of restoring periodontal coverage?

To prevent further dentine loss Signup and view all the answers

What is the primary function of G-proteins in G-protein-coupled receptors?

To deliver messages within the cell Signup and view all the answers

What is the purpose of using Novamin Bioactive Glass?

To strengthen tooth enamel Signup and view all the answers

What is the purpose of using Hydroxyapatite?

To strengthen tooth enamel Signup and view all the answers

What is the role of enzymes in enzyme-linked receptors?

To produce enzymatic products that induce an intracellular response Signup and view all the answers

What is the primary function of ion channels?

To allow charged ions to flow through the cell membrane Signup and view all the answers

What type of stimuli can ion channels respond to?

Various stimuli, including voltage, chemicals, and mechanical stimuli Signup and view all the answers

What type of cells express signalling proteins that can detect temperature changes?

Both odontoblasts and neurons Signup and view all the answers

What is the analogy used to describe the role of G-proteins in G-protein-coupled receptors?

A courier delivering messages Signup and view all the answers

What is the analogy used to describe the role of enzyme-linked receptors?

A chef producing dishes Signup and view all the answers

What type of channels conduct charged ions into and/or out of a cell, causing a change in electrical potential across the membrane?

Ion channels Signup and view all the answers

Which type of neurons are associated with thermo-sensitive channels?

C-type neurons Signup and view all the answers

What is the primary causative factor of dentine hypersensitivity that should be reduced?

Dietary sources of erosive acids Signup and view all the answers

What is the effect of hydrodynamic movement on A-type neurons?

It stimulates them directly Signup and view all the answers

What is the function of TRP channels on odontoblasts?

To release chemical messengers that stimulate A-type fibers Signup and view all the answers

What is the purpose of maintaining the smear layer?

To promote remineralization Signup and view all the answers

What type of channels are associated with pressure sensitivity on A-type neurons and odontoblasts?

Pressure-sensitive channels Signup and view all the answers

What is the effect of odontoblasts releasing chemical messengers?

It stimulates A-type fibers indirectly Signup and view all the answers

What is the primary function of dentine in a tooth?

To form the bulk of the tooth Signup and view all the answers

What is the characteristic of dentinal tubules that make them 'spongy'?

They are composed of hollow tubes Signup and view all the answers

Which of the following has the highest elastic modulus?

Tertiary dentine Signup and view all the answers

What is the relationship between water content, organic content, and mineral content in the hard tissues of the oral cavity?

Water content is inversely proportional to mineral content Signup and view all the answers

What is the hardness range of dentine in GPa?

0.48-1.1 Signup and view all the answers

Which of the following has the highest mineral content?

Enamel Signup and view all the answers

What is the percentage of organic content in bone?

30% Signup and view all the answers

What is the characteristic of dentine that makes it different from other hard tissues?

It is composed of hollow tubes Signup and view all the answers

What is the average diameter of dentinal tubules near the pulp?

1-3 µm Signup and view all the answers

What is the primary function of odontoblasts in relation to dentine?

Maintaining and repairing dentine Signup and view all the answers

What is the characteristic of the pain arising from exposed dentine in response to certain stimuli?

Short, sharp pain Signup and view all the answers

What is the reason why teeth are not always sensitive?

Gingival tissue and smear layer normally protect the dentine Signup and view all the answers

What is the age range at which dentine hypersensitivity typically starts to occur?

15 years and above Signup and view all the answers

What is the characteristic of the fluid found in dentinal tubules?

Slowly moving outwards Signup and view all the answers

What is the type of nerve fibres that innervate the pulp only?

Unmyelinated C fibres Signup and view all the answers

What is the typical response of teeth to certain stimuli when the protective tissues are lost?

Sensitivity Signup and view all the answers

What is the primary purpose of eliminating sources of heavy abrasion in managing dentine hypersensitivity?

To prevent further dentine loss and allow protective layer to build up over tubules Signup and view all the answers

What is the role of fluoride in toothpastes and varnishes in managing dentine hypersensitivity?

To reduce erosion Signup and view all the answers

What is the purpose of placing restorations or sealants in managing dentine hypersensitivity?

To prevent further dentine loss Signup and view all the answers

What is the effect of not brushing teeth immediately after consuming acidic substances?

It prevents further dentine loss Signup and view all the answers

What is the benefit of using toothpastes and mouthwashes with chemical components like Strontium and Novamin?

They reduce erosion Signup and view all the answers

What is the role of cheese, milk, and chewing gum in managing dentine hypersensitivity?

They promote smear layer formation, reducing mouth pH Signup and view all the answers

What is the purpose of restoring periodontal coverage in managing dentine hypersensitivity?

To restore a natural barrier against hypersensitivity Signup and view all the answers

What is the effect of using Biomin F (Fluoride-containing Bioactive Glass) in managing dentine hypersensitivity?

It reduces erosion Signup and view all the answers

What is the primary function of ion channels in neurons?

To conduct charged ions into and/or out of a cell, causing a change in electrical potential across the membrane Signup and view all the answers

Which type of neurons are associated with thermo-sensitive channels?

C-type neurons Signup and view all the answers

What is the effect of hydrodynamic movement on A-type neurons?

Direct stimulation Signup and view all the answers

What is the purpose of reducing dietary sources of erosive acids?

To remove the primary causative factor of dentine hypersensitivity Signup and view all the answers

What type of channels are associated with pressure sensitivity on A-type neurons and odontoblasts?

Pressure-sensitive channels Signup and view all the answers

What is the function of TRP channels on odontoblasts?

To transduce normal temperature sensations Signup and view all the answers

What is the purpose of maintaining the smear layer?

To reduce the permeability of the dentine Signup and view all the answers

What is the effect of odontoblasts releasing chemical messengers?

Indirect stimulation of A-type neurons Signup and view all the answers

What is the primary mechanism by which dentine hypersensitivity arises?

Loss of protection over permeable dentine Signup and view all the answers

What is the role of potassium nitrate in reducing nerve communication?

It prohibits depolarization of excitable cells Signup and view all the answers

Which of the following is a treatment strategy for dentine hypersensitivity?

Reducing the excitability of pulp nociceptors to block pain signal transmission Signup and view all the answers

What is the most widely accepted theory of physiological mechanism of dentine hypersensitivity?

Hydrodynamic theory Signup and view all the answers

What is the role of ion channels in dentine hypersensitivity?

They stimulate responses in odontoblasts and/or neurons Signup and view all the answers

Which of the following is NOT a treatment strategy for dentine hypersensitivity?

Increasing the excitability of pulp nociceptors Signup and view all the answers

What is the role of odontoblasts in dentine hypersensitivity?

They stimulate responses in themselves and/or neurons Signup and view all the answers

What is the result of fluid movement in dentinal tubules?

Stimulation of responses in odontoblasts and/or neurons Signup and view all the answers

Dentistry: Dentine and Dentine Hypersensitivity

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Questions and Answers

What is a mechanism by which odontoblasts may contribute to dental hypersensitivity?

In the context of dental hypersensitivity, what occurs when a tooth is exposed to cold temperatures?

Which of the following is a type of transmembrane receptor?

What is a common characteristic of dentinal tubules in teeth with hypersensitivity?

What is the mechanism by which high osmotic pressure stimulates pain?

What is a limitation of the odontoblast transducer mechanism of dental hypersensitivity?

What is a characteristic of the hydrodynamic theory of dental hypersensitivity?

What is a type of receptor that can be involved in dental hypersensitivity?

What percentage of mineral content is found in enamel?

What is the primary function of dentine tubules?

What is the relationship between water content, organic content, and mineral content in the hard tissues of the oral cavity?

What type of dentine has the highest elastic modulus?

What is the hardness range of dentine in GPa?

Which of the following is a characteristic of dentine?

What percentage of organic content is found in bone?

What is the main difference between primary, secondary, and tertiary dentine?

What is the purpose of not brushing teeth immediately after consuming acidic substances?

What is the role of fluoride in preventing tooth erosion?

What is the purpose of using cheese, milk, or chewing gum?

What is the purpose of sealing or restoring teeth?

What is the purpose of using toothpastes and mouthwashes with chemical components?

What is the common property of transmembrane receptors, enzyme-linked receptors, and ion channels?

What is the purpose of restoring periodontal coverage?

What is the primary function of G-proteins in G-protein-coupled receptors?

What is the purpose of using Novamin Bioactive Glass?

What is the purpose of using Hydroxyapatite?

What is the role of enzymes in enzyme-linked receptors?

What is the primary function of ion channels?

What type of stimuli can ion channels respond to?

What type of cells express signalling proteins that can detect temperature changes?

What is the analogy used to describe the role of G-proteins in G-protein-coupled receptors?

What is the analogy used to describe the role of enzyme-linked receptors?

What type of channels conduct charged ions into and/or out of a cell, causing a change in electrical potential across the membrane?

Which type of neurons are associated with thermo-sensitive channels?

What is the primary causative factor of dentine hypersensitivity that should be reduced?

What is the effect of hydrodynamic movement on A-type neurons?

What is the function of TRP channels on odontoblasts?

What is the purpose of maintaining the smear layer?

What type of channels are associated with pressure sensitivity on A-type neurons and odontoblasts?

What is the effect of odontoblasts releasing chemical messengers?

What is the primary function of dentine in a tooth?

What is the characteristic of dentinal tubules that make them 'spongy'?

Which of the following has the highest elastic modulus?

What is the relationship between water content, organic content, and mineral content in the hard tissues of the oral cavity?

What is the hardness range of dentine in GPa?

Which of the following has the highest mineral content?

What is the percentage of organic content in bone?

What is the characteristic of dentine that makes it different from other hard tissues?

What is the average diameter of dentinal tubules near the pulp?

What is the primary function of odontoblasts in relation to dentine?

What is the characteristic of the pain arising from exposed dentine in response to certain stimuli?

What is the reason why teeth are not always sensitive?

What is the age range at which dentine hypersensitivity typically starts to occur?

What is the characteristic of the fluid found in dentinal tubules?

What is the type of nerve fibres that innervate the pulp only?

What is the typical response of teeth to certain stimuli when the protective tissues are lost?

What is the primary purpose of eliminating sources of heavy abrasion in managing dentine hypersensitivity?

What is the role of fluoride in toothpastes and varnishes in managing dentine hypersensitivity?

What is the purpose of placing restorations or sealants in managing dentine hypersensitivity?

What is the effect of not brushing teeth immediately after consuming acidic substances?

What is the benefit of using toothpastes and mouthwashes with chemical components like Strontium and Novamin?

What is the role of cheese, milk, and chewing gum in managing dentine hypersensitivity?

What is the purpose of restoring periodontal coverage in managing dentine hypersensitivity?

What is the effect of using Biomin F (Fluoride-containing Bioactive Glass) in managing dentine hypersensitivity?

What is the primary function of ion channels in neurons?

Which type of neurons are associated with thermo-sensitive channels?

What is the effect of hydrodynamic movement on A-type neurons?

What is the purpose of reducing dietary sources of erosive acids?

What type of channels are associated with pressure sensitivity on A-type neurons and odontoblasts?

What is the function of TRP channels on odontoblasts?

What is the purpose of maintaining the smear layer?

What is the effect of odontoblasts releasing chemical messengers?

What is the primary mechanism by which dentine hypersensitivity arises?

What is the role of potassium nitrate in reducing nerve communication?

Which of the following is a treatment strategy for dentine hypersensitivity?

What is the most widely accepted theory of physiological mechanism of dentine hypersensitivity?

What is the role of ion channels in dentine hypersensitivity?