Podcast
Questions and Answers
What is the primary function of IL-2 in terms of cytokine-receptor interactions?
What is the primary function of IL-2 in terms of cytokine-receptor interactions?
- Endocrine signaling
- Activation of B cells
- T-cell activation (correct)
- Induction of inflammatory responses
What is a characteristic of cytokines in terms of their production?
What is a characteristic of cytokines in terms of their production?
- They are only produced by T cells
- They are only involved in innate immunity
- They require a stimulus for production (correct)
- They can be produced constitutively
Which type of cytokine binding results in the activation of cells in the immediate vicinity?
Which type of cytokine binding results in the activation of cells in the immediate vicinity?
- Endocrine binding
- Paracrine binding (correct)
- Autocrine binding
- Juxtacrine binding
Which of the following cytokine families includes IL-2 and IL-4?
Which of the following cytokine families includes IL-2 and IL-4?
What is the primary source of cytokines?
What is the primary source of cytokines?
What is a function of cytokines secreted by TH cells?
What is a function of cytokines secreted by TH cells?
What is the primary characteristic of acute phase of inflammation?
What is the primary characteristic of acute phase of inflammation?
Which type of cytokine promotes systemic inflammation?
Which type of cytokine promotes systemic inflammation?
What is the primary function of anti-inflammatory cytokines?
What is the primary function of anti-inflammatory cytokines?
What is the role of cytokines in host responses?
What is the role of cytokines in host responses?
What is the effect of proinflammatory cytokines on disease?
What is the effect of proinflammatory cytokines on disease?
What is the primary difference between proinflammatory and anti-inflammatory cytokines?
What is the primary difference between proinflammatory and anti-inflammatory cytokines?
What is a common feature among the receptors for IL-2, IL-4, and IL-7?
What is a common feature among the receptors for IL-2, IL-4, and IL-7?
What is the consequence of cytokine binding to its receptor?
What is the consequence of cytokine binding to its receptor?
What type of immunity is activated by Th1 cells?
What type of immunity is activated by Th1 cells?
Which of the following cytokines is not typically produced by Th2 cells?
Which of the following cytokines is not typically produced by Th2 cells?
What is the primary target of the cytokine IL-7?
What is the primary target of the cytokine IL-7?
What type of cytokine is IL-10?
What type of cytokine is IL-10?
What is the role of JAKs in cytokine signaling?
What is the role of JAKs in cytokine signaling?
What is the effect of bacterial cell wall endotoxins on macrophages?
What is the effect of bacterial cell wall endotoxins on macrophages?
What is the role of Th2 cells in immune responses?
What is the role of Th2 cells in immune responses?
Which cytokine is a chemokine that primarily targets neutrophils and endothelial cells?
Which cytokine is a chemokine that primarily targets neutrophils and endothelial cells?
What is the consequence of a defective γ chain in X-linked severe combined immunodeficiency disease (SCID)?
What is the consequence of a defective γ chain in X-linked severe combined immunodeficiency disease (SCID)?
What type of bacteria can cause bacterial septic shock?
What type of bacteria can cause bacterial septic shock?
What is the result of phosphorylation of STATs by JAKs?
What is the result of phosphorylation of STATs by JAKs?
What is a common symptom of bacterial septic shock?
What is a common symptom of bacterial septic shock?
What is the primary mechanism by which bacterial septic shock develops?
What is the primary mechanism by which bacterial septic shock develops?
What is one of the roles of cytokines in immune responses?
What is one of the roles of cytokines in immune responses?
What is a potential therapeutic strategy for treating bacterial septic shock?
What is a potential therapeutic strategy for treating bacterial septic shock?
