Connective Tissue Components and Blood Cells Quiz

White Blood Cells or Transient Cells migrate to connective tissue to act as a response during ______

Macrophages, Mast Cells, Plasma Cells, and Leukocytes are examples of ______

Glycosaminoglycans are long polymers of repeating disaccharide units, usually a hexosamine and ______ acid

Hyaluronic acid is the ______ and most ubiquitous GAG

Plasma Cells consist of a core protein to which are covalently attached various numbers and combinations of the sulfated GAGs bind to ______ acid

Aggrecan is a large, core protein heavily bound with chondroitin and keratan sulfate ______

Connective tissue is specialized to physically support and connect other tissues and maintain the water required for metabolite diffusion to and from cells. Connective tissue cells are scattered throughout the extracellular matrix which consists of large protein fibers and glycoproteins attached to the basement membrane. Epithelial tissues cells form a sheet-like structure or lines our organ. 3 components of connective tissue are cells, ground substance, and _______.

Connective tissue is responsible for attachment of one tissue to another. Examples include Ligaments, Tendons. Another function is the transport of fluids and materials, for example, _______.

Connective tissue plays a role in defending the body from invading microorganisms. This function is particularly important in the _______ system.

Connective tissue is involved in storage of materials, for example, _______.

Connective tissue is important in establishing a structural framework for the body. Examples include _______.

Fibroblasts, the major cells of connective tissue proper, are elongated, irregularly shaped cells with oval nuclei that synthesize and secrete most components of the ECM. Fibroblasts are targets of many families of proteins called growth factors that influence cell growth and differentiation. Fibroblasts originate from embryonic _______.

Function in ECM turnover, ______ of dead cells and debris, and antigen presentation to lymphocytes; secretion of growth factors, cytokines, and other agents “histiocytes” 2|Page MONONUCLEAR PHAGOCYTE SYSTEM MAJOR CELL TYPE MAIN FUNCTION LOCATION Precursor of MONOCYTE Blood macrophages Production of cytokines, Connective chemotactic tissue, lymphoid factors, and organs, lungs, several other MACROPHAGE bone marrow, molecules that pleural and participate in peritoneal inflammation cavities (defense), antigen processing, and presentation Liver Same as KUPFFER CELL (perisinusoidal) macrophages MICROGLIAL Central Nervous Same as CELL System macrophages Antigen LANGERHANS Epidermis of skin processing and CELL presentation Transcribed by: JAMARA DENDRITIC CELL Lymph nodes, spleen Antigen processing and presentation OSTEOCLAST (FROM FUSION OF SEVERAL MACROPHAGES) Bone Localized digestion of bone matrix MULTINUCLEAR GIANT CELL (SEVERAL FUSED MACROPHAGES) In connective tissue under various pathological conditions Segregation and digestion of foreign bodies FIXED OR RESIDENT CELLS - Mesenchymal cells - Fibroblasts/Fibrocytes, Adipocytes GROUND SUBSTANCE Clear area of the connective tissue an amorphous transparent material with the physical character of semi-solid gel that fills the space (largely unstained extracellular material) between cells and fibers in connective tissue a mixture of glycoproteins and complex carbohydrates with profound water-binding ability.I.

The precursor of MONOCYTE is found in the ______

MACROPHAGE is responsible for antigen processing and ______

MICROGLIAL cells are found in the ______ System

DENDRITIC CELL is responsible for antigen processing and ______

OSTEOCLAST is involved in localized digestion of ______ matrix