Congenital Adrenal Hyperplasia Metabolic Disorders
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Questions and Answers

What is the typical weight range of the adrenals in cases of adrenal carcinoma?

  • Over 100 gm (correct)
  • 60-80 gm
  • 30-40 gm
  • 80-100 gm

Which histological feature is NOT associated with determining malignancy in adrenal carcinomas?

  • Broad fibrous bands
  • Atypical mitoses
  • Necrosis
  • Hypertrophy (correct)

In cases of adrenal atrophy due to exogenous steroid hormones, what is the typical combined weight of the affected glands?

  • 10-20 gm
  • 60-70 gm
  • 3-6 gm (correct)
  • 20-30 gm

Which disorder is characterized by primary hyperaldosteronism and is often caused by an aldosterone-secreting adenoma?

<p>Conn's syndrome (D)</p> Signup and view all the answers

What are the typical clinical manifestations of primary hyperaldosteronism?

<p>Hypokalemia, sodium retention, hypertension and decreased plasma renin activity (D)</p> Signup and view all the answers

In cases of adrenal cortical hyperplasia, what type of cells are widened in the cortex?

<p>Reticularis type cells (B)</p> Signup and view all the answers

What is a reliable diagnostic criterion for malignancy in cases of adrenal carcinoma?

<p>Metastatic spread (C)</p> Signup and view all the answers

Which type of carcinoma is derived from para-follicular or C-cells of the thyroid and produces calcitonin?

<p>Medullary carcinoma (D)</p> Signup and view all the answers

What genetic defect is associated with medullary carcinoma of the thyroid?

<p>Chromosome 10 (D)</p> Signup and view all the answers

Which type of hyperparathyroidism is often associated with chronic renal failure?

<p>Secondary hyperparathyroidism (C)</p> Signup and view all the answers

What is a common cause of hypoparathyroidism?

<p>Familial syndrome (A)</p> Signup and view all the answers

Characterized by excessive production of ACTH, Cushing's syndrome is most commonly due to lesions in which part of the body?

<p>Pituitary or hypothalamus (C)</p> Signup and view all the answers

In cases of hyperadrenalism, about what percentage of tumors produce ectopic ACTH leading to bilateral adrenal hyperplasia?

<p>10 - 15% (D)</p> Signup and view all the answers

What is the most common type of tumor causing Cushing's syndrome?

<p>Pituitary adenoma (C)</p> Signup and view all the answers

Which disorder is characterized by hereditary primary adrenocortical insufficiency?

<p>Addison's disease (A)</p> Signup and view all the answers

Which genetic disorder is responsible for Pseudohypoparathyroidism?

<p>DiGeorge's Syndrome (D)</p> Signup and view all the answers

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