Congenital Adrenal Hyperplasia Metabolic Disorders

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What is the typical weight range of the adrenals in cases of adrenal carcinoma?

Over 100 gm (correct)

60-80 gm

30-40 gm

80-100 gm

Which histological feature is NOT associated with determining malignancy in adrenal carcinomas?

Broad fibrous bands

Atypical mitoses

Necrosis

Hypertrophy (correct)

In cases of adrenal atrophy due to exogenous steroid hormones, what is the typical combined weight of the affected glands?

10-20 gm

60-70 gm

3-6 gm (correct)

20-30 gm

Which disorder is characterized by primary hyperaldosteronism and is often caused by an aldosterone-secreting adenoma?

Conn's syndrome Signup and view all the answers

What are the typical clinical manifestations of primary hyperaldosteronism?

Hypokalemia, sodium retention, hypertension and decreased plasma renin activity Signup and view all the answers

In cases of adrenal cortical hyperplasia, what type of cells are widened in the cortex?

Reticularis type cells Signup and view all the answers

What is a reliable diagnostic criterion for malignancy in cases of adrenal carcinoma?

Metastatic spread Signup and view all the answers

Which type of carcinoma is derived from para-follicular or C-cells of the thyroid and produces calcitonin?

Medullary carcinoma Signup and view all the answers

What genetic defect is associated with medullary carcinoma of the thyroid?

Chromosome 10 Signup and view all the answers

Which type of hyperparathyroidism is often associated with chronic renal failure?

Secondary hyperparathyroidism Signup and view all the answers

What is a common cause of hypoparathyroidism?

Familial syndrome Signup and view all the answers

Characterized by excessive production of ACTH, Cushing's syndrome is most commonly due to lesions in which part of the body?

Pituitary or hypothalamus Signup and view all the answers

In cases of hyperadrenalism, about what percentage of tumors produce ectopic ACTH leading to bilateral adrenal hyperplasia?

10 - 15% Signup and view all the answers

What is the most common type of tumor causing Cushing's syndrome?

Pituitary adenoma Signup and view all the answers

Which disorder is characterized by hereditary primary adrenocortical insufficiency?

Addison's disease Signup and view all the answers

Which genetic disorder is responsible for Pseudohypoparathyroidism?

DiGeorge's Syndrome Signup and view all the answers

Congenital Adrenal Hyperplasia Metabolic Disorders

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