Podcast
Questions and Answers
What is the initial, primary development of the CNS that occurs?
What is the initial, primary development of the CNS that occurs?
- Axon growth
- Neural proliferation
- Induction of the neural plate (correct)
- Synapse formation
Consider the development of the CNS. What is the correct order of these stages?
Consider the development of the CNS. What is the correct order of these stages?
- Induction of the neural plate, neural proliferation, neural tube formation, axon growth
- Neural tube formation, induction of the neural plate, neural proliferation, axon growth
- Induction of the neural plate, neural tube formation, neural proliferation, axon growth (correct)
- Neural proliferation, neural tube formation, induction of the neural plate, axon growth
Which of the following is NOT a critical step in the development of neurons once they are formed?
Which of the following is NOT a critical step in the development of neurons once they are formed?
- Migration to the appropriate location
- Mitotic division (correct)
- Differentiation
- Synapse formation
Gene and environmental influences are important to the development of the CNS, but what is especially emphasized in the case of “Genie”?
Gene and environmental influences are important to the development of the CNS, but what is especially emphasized in the case of “Genie”?
What does the example of “Genie” illustrate regarding the role of genes and the environment in the development of the CNS?
What does the example of “Genie” illustrate regarding the role of genes and the environment in the development of the CNS?
What are the two key factors that continuously interact throughout the development of the CNS?
What are the two key factors that continuously interact throughout the development of the CNS?
What is a key concept that challenges the traditional view of the brain as a stable organ after childhood?
What is a key concept that challenges the traditional view of the brain as a stable organ after childhood?
When the neural plate develops, where does the initial signal for the induction come from?
When the neural plate develops, where does the initial signal for the induction come from?
What is the primary purpose of gastrulation in embryonic development?
What is the primary purpose of gastrulation in embryonic development?
What technique is used in the study of zebrafish embryos, as mentioned in the provided references?
What technique is used in the study of zebrafish embryos, as mentioned in the provided references?
Which of the following is NOT a key factor contributing to the development of the central nervous system (CNS)?
Which of the following is NOT a key factor contributing to the development of the central nervous system (CNS)?
Which of the following is an example of a technique used to visualize neural structures, as mentioned in the references?
Which of the following is an example of a technique used to visualize neural structures, as mentioned in the references?
According to the provided references, what is a major challenge in understanding the development of the CNS?
According to the provided references, what is a major challenge in understanding the development of the CNS?
During neuronal development, which of the following is NOT a reason for neuronal death?
During neuronal development, which of the following is NOT a reason for neuronal death?
Which of the following is NOT a function of neurotrophins?
Which of the following is NOT a function of neurotrophins?
What is the main function of the process of neuronal cell death during development?
What is the main function of the process of neuronal cell death during development?
Which type of cell death is characterized as a 'clean' process?
Which type of cell death is characterized as a 'clean' process?
Why are developing neurons considered 'promiscuous' in terms of connections?
Why are developing neurons considered 'promiscuous' in terms of connections?
Which of the following is NOT a neurotrophin?
Which of the following is NOT a neurotrophin?
During neuronal development, what is the main outcome of competition for target-supplied neurotrophins?
During neuronal development, what is the main outcome of competition for target-supplied neurotrophins?
What is the significance of the fact that developing neurons make more focused synapses?
What is the significance of the fact that developing neurons make more focused synapses?
According to the Chemoaffinity Hypothesis, how do axons find their target?
According to the Chemoaffinity Hypothesis, how do axons find their target?
What type of evidence contradicts the Chemoaffinity Hypothesis?
What type of evidence contradicts the Chemoaffinity Hypothesis?
What is the role of fasciculation in axonal guidance?
What is the role of fasciculation in axonal guidance?
Which of these is NOT an example of evidence supporting the Topographic Gradient Hypothesis?
Which of these is NOT an example of evidence supporting the Topographic Gradient Hypothesis?
Which of these is NOT part of the revised Chemoaffinity Hypothesis?
Which of these is NOT part of the revised Chemoaffinity Hypothesis?
What type of cell is crucial for synapse formation?
What type of cell is crucial for synapse formation?
Which of the following is a key point in the Topographic Gradient Hypothesis?
Which of the following is a key point in the Topographic Gradient Hypothesis?
What is the significance of the fact that the frog optic tectum is homologous to the mammalian superior colliculus?
What is the significance of the fact that the frog optic tectum is homologous to the mammalian superior colliculus?
Which of these cell types is considered pluripotent?
Which of these cell types is considered pluripotent?
Which of the following is NOT a characteristic of totipotent stem cells?
Which of the following is NOT a characteristic of totipotent stem cells?
What type of stem cell is responsible for the development of neurons and glia of the peripheral nervous system (PNS)?
What type of stem cell is responsible for the development of neurons and glia of the peripheral nervous system (PNS)?
Which of the following cell types is NOT a derivative of the neural crest?
Which of the following cell types is NOT a derivative of the neural crest?
What is the significance of the mesoderm in the development of the neural plate?
What is the significance of the mesoderm in the development of the neural plate?
What is the main difference between totipotent and pluripotent stem cells?
What is the main difference between totipotent and pluripotent stem cells?
Which of the following is an example of a multipotent stem cell?
Which of the following is an example of a multipotent stem cell?
What is the significance of a chicken with teeth?
What is the significance of a chicken with teeth?
Which of the following is NOT a type of neural migration?
Which of the following is NOT a type of neural migration?
What is the primary function of cell adhesion molecules (CAMs) in neural development?
What is the primary function of cell adhesion molecules (CAMs) in neural development?
What is the defining characteristic of "smooth brain" or lissencephaly?
What is the defining characteristic of "smooth brain" or lissencephaly?
What is the primary role of the floor plate and roof plate in neural proliferation?
What is the primary role of the floor plate and roof plate in neural proliferation?
Which disorder is linked to a faulty cell adhesion molecule (CAM) protein?
Which disorder is linked to a faulty cell adhesion molecule (CAM) protein?
What is the main role of the growth cone in axonal growth?
What is the main role of the growth cone in axonal growth?
Which of the following statements accurately describes how the chemoaffinity hypothesis explains axonal growth?
Which of the following statements accurately describes how the chemoaffinity hypothesis explains axonal growth?
What is the correct order of events in neural development, from early to late?
What is the correct order of events in neural development, from early to late?
Flashcards
Prenatal Development
Prenatal Development
The stage of CNS development that occurs before birth.
Postnatal Development
Postnatal Development
CNS development that occurs after birth, through childhood to adulthood.
Brain Plasticity
Brain Plasticity
The ability of the brain to change throughout life.
Gametogenesis
Gametogenesis
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Neural Plate Induction
Neural Plate Induction
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Neural Tube
Neural Tube
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Neurodevelopment Disorders
Neurodevelopment Disorders
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Neuron Migration
Neuron Migration
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Neural Crest
Neural Crest
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Cellular Differentiation
Cellular Differentiation
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Stem Cells
Stem Cells
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Totipotent Stem Cells
Totipotent Stem Cells
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Pluripotent Stem Cells
Pluripotent Stem Cells
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Multipotent Stem Cells
Multipotent Stem Cells
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Unipotent Stem Cells
Unipotent Stem Cells
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Embryonic Stages
Embryonic Stages
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Neural Proliferation
Neural Proliferation
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Vesicles Formation
Vesicles Formation
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Ventricular Zone Proliferation
Ventricular Zone Proliferation
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Chemical Signals in Neural Development
Chemical Signals in Neural Development
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Types of Neural Migration
Types of Neural Migration
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Cell Adhesion Molecules (CAMs)
Cell Adhesion Molecules (CAMs)
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Kallmann Syndrome
Kallmann Syndrome
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Axon Growth Cone
Axon Growth Cone
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Chemoaffinity Hypothesis
Chemoaffinity Hypothesis
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Sperry’s Study
Sperry’s Study
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Target Incorrect Innervation
Target Incorrect Innervation
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Fasciculation
Fasciculation
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Topographic Gradient Hypothesis
Topographic Gradient Hypothesis
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Synaptogenesis
Synaptogenesis
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Role of Astrocytes
Role of Astrocytes
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Pioneer Growth Cones
Pioneer Growth Cones
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In vivo studies
In vivo studies
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Neuron death reasons
Neuron death reasons
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Apoptosis
Apoptosis
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Necrosis
Necrosis
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Neurotrophins
Neurotrophins
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Neuron connection surplus
Neuron connection surplus
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Synaptic accuracy
Synaptic accuracy
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Functions of neurotrophins
Functions of neurotrophins
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Gastrulation
Gastrulation
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Acetylated α-tubulin
Acetylated α-tubulin
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Zebrafish Embryo
Zebrafish Embryo
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Light-sheet Fluorescence Microscopy
Light-sheet Fluorescence Microscopy
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Immunostaining
Immunostaining
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