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Clinical Chemistry Laboratory: Specimen Collection and QA

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30 Questions

What is the primary purpose of a centrifuge in a Clinical Chemistry laboratory?

To separate serum or plasma from blood

What is the main function of Autoanalyzers in Clinical Chemistry and Immunology?

To automate chemistry and immunology tests

What is the purpose of Quality Assurance (QA) in a Clinical Chemistry laboratory?

To monitor and control the quality of testing processes and results

What is the role of the laboratory in the clinical work cycle?

To receive and process specimens from patients

What is the purpose of the request form in the laboratory work cycle?

To initiate the testing process and specify required tests

What is the primary focus of the discipline of Clinical Biochemistry?

The study of the chemical and biochemical processes of the body

What is the primary reason for rejecting a blood specimen with the presence of a needle?

Contamination risk

What is the most common cause of lipaemic blood?

Failing to fast before blood collection

What is the primary purpose of a pre-analytical system in laboratory automation?

To prepare blood samples for analysis

What is the result of delayed plasma or serum separation from blood?

Hemolysis

What is the primary factor affecting the quality of a blood sample?

All of the above

What percentage of laboratory errors are attributed to the pre-analytical process?

60%

What is the primary purpose of calibration in laboratory analysis?

To establish a standard for quality control

Which type of specimen is often transported on ice due to its unstable analytes?

Unstable analytes

What is the primary function of auto-analysers in clinical chemistry laboratories?

To analyze thousands of tests per day

Which step in the laboratory analysis process involves the calculation and compilation of data collected?

Post-analysis

What is the primary purpose of stringent quality assurance in clinical chemistry laboratories?

To maintain the integrity of the testing process from sample collection to result reporting

Which type of laboratory is exempt from using auto-analysers for daily high-throughput testing?

Urgent laboratory

What is the primary reason why hemolysed blood affects the measurement of certain analytes?

Intracellular release of ions and enzymes into plasma/serum

Which of the following analytical interferences is caused by elevated triglyceride levels in a sample?

Lipemia

Which of the following physiological factors can affect the measurement of cortisol levels in a sample?

Sampling time

What is the purpose of the Serum Index (Roche) in laboratory analysis?

To indicate the extent of interference to target analyte analysis

Which of the following pre-analytical factors can affect the measurement of blood gas levels in a sample?

All of the above

Which of the following analytes is affected by the use of EDTA blood instead of heparin blood?

Potassium

What is the primary mechanism by which lipoproteins interfere with antigen-antibody reactions in immunoassays?

By blocking the binding sites of antibodies, thereby reducing the reaction

Which of the following is an example of an endogenous interference in laboratory testing?

Glucose interference in osmolality measurement

What is the primary purpose of the Westgard Rules in quality control charts?

To monitor and control analytical instrument performance

What is the primary goal of total laboratory automation (TLA) in clinical chemistry laboratories?

To automate the entire laboratory testing process

Which of the following is a potential source of error in the post-analytical phase of laboratory testing?

Transcription errors in result reporting

What is the primary focus of the pre-analytical phase management in laboratory testing?

Managing patient preparation and sample collection

Test your knowledge on the clinical chemistry laboratory, including specimen collection, quality assurance, and instrumentation. This quiz covers the reception and transportation of specimens, centrifugation, and more.

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