Cleft Lip and Palate Etiology and Development
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Questions and Answers

During which weeks of pregnancy does the lip form?

  • 1st and 2nd weeks
  • 10th and 12th weeks
  • 6th and 9th weeks
  • 4th and 7th weeks (correct)

Which failure of fusion leads to the formation of the primary palate?

  • Lateral palatine shelf with nasal septum
  • Intermaxillary segment with maxillary process (correct)
  • Two lateral palatine shelves
  • Lateral palatine shelf with maxillary process

At what stage is cleft lip typically detected on ultrasound?

  • 20th week of pregnancy
  • 6th week of pregnancy
  • 27th week of pregnancy
  • 13th week of pregnancy (correct)

What is the cause of cleft palate?

<p>Failure of lateral palatine shelves to fuse (C)</p> Signup and view all the answers

Which structure is affected by a cleft palate?

<p>Roof of the mouth (palate) (A)</p> Signup and view all the answers

What are some common issues associated with cleft lip?

<p><strong>Speech issues</strong>, <strong>feeding issues</strong>, <strong>oral hygiene issues</strong> (B)</p> Signup and view all the answers

In which stage of pregnancy is the roof of the mouth (palate) formed?

<p><strong>6th and 9th weeks</strong> (B)</p> Signup and view all the answers

What structures are formed by the first pharyngeal pouch?

<p>Portions of the inner ear (D)</p> Signup and view all the answers

Which cranial nerve is responsible for sensation in the first pharyngeal arch?

<p>CN V-5 (A)</p> Signup and view all the answers

Which gland is formed from the ventral part of the third pharyngeal pouch?

<p>Thymus (A)</p> Signup and view all the answers

What is the main cause of Treacher Collins Syndrome?

<p>Failure of neural crest cell migration (A)</p> Signup and view all the answers

Which cranial nerve is associated with taste in the second pharyngeal arch?

<p>CN VII-7 (D)</p> Signup and view all the answers

In Treacher Collins Syndrome, which of the following facial bones are typically underdeveloped?

<p>Mandible and jaw (A)</p> Signup and view all the answers

Which glandular structure is formed by the ultimobranchial body from the fourth pharyngeal pouch?

<p>Calcitonin-producing C-cells (A)</p> Signup and view all the answers

Which of the following is a classic triad associated with DiGeorge Syndrome?

<p>Loss of thymus, loss of parathyroid glands, congenital heart defects (A)</p> Signup and view all the answers

Which pharyngeal pouches are affected in Arytenoid DiGeorge Syndrome?

<p>3rd and 4th pharyngeal pouches (C)</p> Signup and view all the answers

Which structure is derived from the 1st pharyngeal cleft?

<p>External auditory meatus (D)</p> Signup and view all the answers

A mass located below the angle of the mandible and anterior to the sternocleidomastoid muscle is most likely a result of which condition?

<p>Branchial cleft cyst (D)</p> Signup and view all the answers

Which craniofacial malformation is considered the most common?

<p>Cleft lip (A)</p> Signup and view all the answers

What is a distinguishing feature between a Branchial cleft cyst and a thyroglossal duct cyst?

<p>Ability to move with swallowing (B)</p> Signup and view all the answers

Which cranial nerve is primarily involved in innervating the muscles of mastication?

<p>Cranial Nerve V (Trigeminal) (A)</p> Signup and view all the answers

Which embryonic structure is key for the development of the head and neck?

<p>Pharyngeal arches (D)</p> Signup and view all the answers

From which pharyngeal arch does the Mandibular Process give rise to the Mandible?

<p>1st arch (C)</p> Signup and view all the answers

Which nerve is associated with the development of the Muscles of Mastication?

<p>CN V (5) (B)</p> Signup and view all the answers

Which structure is derived from Reichert’s Cartilage of the 2nd Arch?

<p>Stapes (A)</p> Signup and view all the answers

The Posterior Digastric muscle is innervated by which cranial nerve?

<p>CN VII (7) (A)</p> Signup and view all the answers

Which embryonic vessel is involuted in development and does not persist into adulthood?

<p>Stapedial Artery (A)</p> Signup and view all the answers

Which pharyngeal arch gives rise to the Laryngeal muscles?

<p>4th Arch (C)</p> Signup and view all the answers

'Treacher Collins Syndrome' mainly affects which structures in the head and neck?

<p>'1st Arch: forms the face' statement (C)</p> Signup and view all the answers

Flashcards

Cleft Lip Formation Weeks

Cleft lip typically forms during the 4th and 7th weeks of pregnancy.

Primary Palate Fusion

The primary palate forms when the intermaxillary segment and maxillary process don't fuse properly.

Ultrasound Detection of Cleft Lip

Cleft lip is often detectable on ultrasound during the 13th week of pregnancy.

Cleft Palate Cause

Cleft palate is caused by a failure of the lateral palatine shelves to fuse.

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Cleft Palate Affected Structure

A cleft palate affects the roof of the mouth (palate).

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Cleft Lip Issues

Common issues associated with cleft lip include speech problems, feeding difficulties, and oral hygiene complications.

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Palate Formation Weeks

The palate forms during the 6th and 9th weeks of pregnancy.

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1st Pharyngeal Pouch Structures

Portions of the inner ear develop from the first pharyngeal pouch.

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1st Pharyngeal Arch Sensation

Cranial Nerve V (Trigeminal) is responsible for sensation in the first pharyngeal arch.

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3rd Pharyngeal Pouch Gland

The thymus develops from the ventral part of the third pharyngeal pouch.

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Treacher Collins Syndrome Cause

Treacher Collins Syndrome is caused by a failure of neural crest cell migration.

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2nd Arch Taste Nerve

Cranial Nerve VII (Facial) is associated with taste in the second pharyngeal arch.

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Treacher Collins Facial Bones

In Treacher Collins Syndrome, the mandible and jaw bones are typically underdeveloped.

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Calcitonin Gland Origin

Calcitonin-producing C-cells are derived from the ultimobranchial body of the fourth pharyngeal pouch.

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DiGeorge Syndrome Triad

A classic triad associated with DiGeorge Syndrome is the loss of thymus, parathyroid glands, and congenital heart defects.

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Arytenoid DiGeorge Pharyngeal Pouches

Arytenoid DiGeorge Syndrome affects the 3rd and 4th pharyngeal pouches.

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1st Pharyngeal Cleft Structure

The first pharyngeal cleft gives rise to the external auditory meatus (ear canal).

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Branchial Cleft Cyst Location

A branchial cleft cyst is typically located below the angle of the mandible, anterior to the sternocleidomastoid muscle.

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Common Craniofacial Malformation

Cleft lip is the most common craniofacial malformation.

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Branchial vs Thyroglossal Cysts

A distinguishing feature between a branchial cleft cyst and a thyroglossal duct cyst is that the former cannot move with swallowing.

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Mastication Nerve

Cranial Nerve V (Trigeminal) is mainly involved in innervating the muscles of mastication (chewing).

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Head & Neck Development Structure

Pharyngeal arches are key embryonic structures for head and neck development.

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Mandible Development Arch

Mandible develops from the mandibular process of the first pharyngeal arch.

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Muscle of Mastication Nerve

Cranial nerve 5 (Trigeminal) is the nerve for the muscles of mastication.

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Stapes Origin

Reichert's cartilage from the second arch forms the stapes.

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Posterior Digastric Nerve

The nerve for the posterior digastric muscle is cranial nerve 7 (facial).

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Non-Persistent Embryonic Vessel

The stapedial artery is an embryonic vessel that doesn't stay in adults.

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Laryngeal Muscles Arch

Laryngeal muscles originate from the fourth pharyngeal arch.

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Treacher Collins Syndrome Structures

Treacher Collins syndrome mainly affects structures formed by the first pharyngeal arch, including facial bones.

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