Cholinergic Transmission and Parasympathomimetics
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Questions and Answers

What is the effect of low doses of atropine on the heart rate?

  • Tachycardia
  • Arrhythmia
  • No effect
  • Bradycardia (correct)

    • What is the name of the device used to administer scopolamine for motion sickness?

  • Transderm Scop (correct)
  • Scopderm
  • Belladona Patch
  • Atropine Trolley

    • What is the Italian phrase for 'beautiful lady' that is associated with atropine?

  • Bella donna
  • Belladona (correct)
  • Dolce vita
  • Bella vita

    • What is the effect of atropine on the eye in patients with glaucoma?

    <p>Increases intraocular pressure</p> Signup and view all the answers

    What is the therapeutic application of atropine in emergency situations?

    <p>Management of emergency bradycardia</p> Signup and view all the answers

    What is the primary effect of scopolamine on the central nervous system?

    <p>Anticholinergic effects</p> Signup and view all the answers

    What is the primary limitation of using Acetylcholine as a therapeutic agent?

    <p>It is rapidly broken down by enzymes in the synaptic cleft</p> Signup and view all the answers

    Which of the following is a characteristic of indirectly acting cholinergic agonists?

    <p>They inhibit the breakdown of Acetylcholine by enzymes</p> Signup and view all the answers

    What is the primary mechanism of action of Pilocarpine?

    <p>Binding directly to muscarinic acetylcholine receptors</p> Signup and view all the answers

    Which of the following is a nicotinic acetylcholine receptor antagonist?

    <p>Edrophonium</p> Signup and view all the answers

    What is the primary difference between directly and indirectly acting cholinergic agonists?

    <p>Their mechanism of action on cholinergic neurons</p> Signup and view all the answers

    What is the therapeutic use of Neostigmine?

    <p>Treating myasthenia gravis</p> Signup and view all the answers

    What is the primary mechanism of action of circulating antibodies in myasthenia gravis?

    <p>Blocking acetylcholine receptors at the postsynaptic neuromuscular junction</p> Signup and view all the answers

    What is the purpose of administering edrophonium chloride in the diagnosis of myasthenia gravis?

    <p>To increase the levels of acetylcholine at the neuromuscular junction</p> Signup and view all the answers

    What is the primary therapeutic application of scopolamine?

    <p>Treatment of motion sickness</p> Signup and view all the answers

    What is the primary action of cholinesterase inhibitors in the treatment of myasthenia gravis?

    <p>Directly improving muscle function</p> Signup and view all the answers

    What is the primary mechanism of action of parasympatholytics?

    <p>Blocking the actions of acetylcholine at the muscarinic receptors</p> Signup and view all the answers

    What is the primary nursing implication related to the use of parasympatholytic drugs?

    <p>Monitoring for anticholinergic side effects</p> Signup and view all the answers

    What is the therapeutic application of Pilocarpine?

    <p>Lowering of IOP in chronic simple glaucoma</p> Signup and view all the answers

    What is the reason why acetylcholine is therapeutically of no importance?

    <p>It has a multiplicity of actions</p> Signup and view all the answers

    Which drug is used to treat conditions associated with increased muscle tone?

    <p>Botulinum toxin</p> Signup and view all the answers

    What is the mechanism of action of Botulinum toxin?

    <p>Inhibition of ACh release</p> Signup and view all the answers

    What is the primary effect of pilocarpine on the eye when applied topically?

    <p>Miosis and contraction of the ciliary body</p> Signup and view all the answers

    Which drug is used to relieve abdominal pain in colics?

    <p>Buscopan</p> Signup and view all the answers

    What is the primary use of neostigmine in medical therapy?

    <p>To treat myasthenia gravis</p> Signup and view all the answers

    What is the therapeutic application of Scopolamine?

    <p>Motion sickness and relieve spasms and colics</p> Signup and view all the answers

    What is the primary adverse effect of pilocarpine hydrochloride 1% ophthalmic solution?

    <p>Spasm of accommodation</p> Signup and view all the answers

    What is the term for the 'grave muscle weakness' disease that is treated with neostigmine?

    <p>Myasthenia gravis</p> Signup and view all the answers

    What is the mechanism of action of Neostigmine?

    <p>Enzymatic inactivation of AChE</p> Signup and view all the answers

    What is the primary effect of acetylcholine on the heart rate?

    <p>Decrease</p> Signup and view all the answers

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