30 Questions
What is the effect of low doses of atropine on the heart rate?
Bradycardia
What is the name of the device used to administer scopolamine for motion sickness?
Transderm Scop
What is the Italian phrase for 'beautiful lady' that is associated with atropine?
Belladona
What is the effect of atropine on the eye in patients with glaucoma?
Increases intraocular pressure
What is the therapeutic application of atropine in emergency situations?
Management of emergency bradycardia
What is the primary effect of scopolamine on the central nervous system?
Anticholinergic effects
What is the primary limitation of using Acetylcholine as a therapeutic agent?
It is rapidly broken down by enzymes in the synaptic cleft
Which of the following is a characteristic of indirectly acting cholinergic agonists?
They inhibit the breakdown of Acetylcholine by enzymes
What is the primary mechanism of action of Pilocarpine?
Binding directly to muscarinic acetylcholine receptors
Which of the following is a nicotinic acetylcholine receptor antagonist?
Edrophonium
What is the primary difference between directly and indirectly acting cholinergic agonists?
Their mechanism of action on cholinergic neurons
What is the therapeutic use of Neostigmine?
Treating myasthenia gravis
What is the primary mechanism of action of circulating antibodies in myasthenia gravis?
Blocking acetylcholine receptors at the postsynaptic neuromuscular junction
What is the purpose of administering edrophonium chloride in the diagnosis of myasthenia gravis?
To increase the levels of acetylcholine at the neuromuscular junction
What is the primary therapeutic application of scopolamine?
Treatment of motion sickness
What is the primary action of cholinesterase inhibitors in the treatment of myasthenia gravis?
Directly improving muscle function
What is the primary mechanism of action of parasympatholytics?
Blocking the actions of acetylcholine at the muscarinic receptors
What is the primary nursing implication related to the use of parasympatholytic drugs?
Monitoring for anticholinergic side effects
What is the therapeutic application of Pilocarpine?
Lowering of IOP in chronic simple glaucoma
What is the reason why acetylcholine is therapeutically of no importance?
It has a multiplicity of actions
Which drug is used to treat conditions associated with increased muscle tone?
Botulinum toxin
What is the mechanism of action of Botulinum toxin?
Inhibition of ACh release
What is the primary effect of pilocarpine on the eye when applied topically?
Miosis and contraction of the ciliary body
Which drug is used to relieve abdominal pain in colics?
Buscopan
What is the primary use of neostigmine in medical therapy?
To treat myasthenia gravis
What is the therapeutic application of Scopolamine?
Motion sickness and relieve spasms and colics
What is the primary adverse effect of pilocarpine hydrochloride 1% ophthalmic solution?
Spasm of accommodation
What is the term for the 'grave muscle weakness' disease that is treated with neostigmine?
Myasthenia gravis
What is the mechanism of action of Neostigmine?
Enzymatic inactivation of AChE
What is the primary effect of acetylcholine on the heart rate?
Decrease
Test your knowledge of cholinergic transmission and parasympathomimetics, including the classification of directly and indirectly acting cholinergic agonists, their actions, and therapeutic uses. Learn about Acetylcholine, Pilocarpine, and Neostigmine, and their roles in the parasympathetic nervous system.
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