Cholinergic Transmission and Parasympathomimetics

Play an AI-generated podcast conversation about this lesson

What is the effect of low doses of atropine on the heart rate?

Tachycardia
Arrhythmia
No effect
Bradycardia (correct)

What is the name of the device used to administer scopolamine for motion sickness?

Transderm Scop (correct)
Scopderm
Belladona Patch
Atropine Trolley

What is the Italian phrase for 'beautiful lady' that is associated with atropine?

Bella donna
Belladona (correct)
Dolce vita
Bella vita

What is the effect of atropine on the eye in patients with glaucoma?

Increases intraocular pressure (B) Signup and view all the answers

What is the therapeutic application of atropine in emergency situations?

Management of emergency bradycardia (B) Signup and view all the answers

What is the primary effect of scopolamine on the central nervous system?

Anticholinergic effects (C) Signup and view all the answers

What is the primary limitation of using Acetylcholine as a therapeutic agent?

It is rapidly broken down by enzymes in the synaptic cleft (B) Signup and view all the answers

Which of the following is a characteristic of indirectly acting cholinergic agonists?

They inhibit the breakdown of Acetylcholine by enzymes (C) Signup and view all the answers

What is the primary mechanism of action of Pilocarpine?

Binding directly to muscarinic acetylcholine receptors (C) Signup and view all the answers

Which of the following is a nicotinic acetylcholine receptor antagonist?

Edrophonium (A) Signup and view all the answers

What is the primary difference between directly and indirectly acting cholinergic agonists?

Their mechanism of action on cholinergic neurons (C) Signup and view all the answers

What is the therapeutic use of Neostigmine?

Treating myasthenia gravis (B) Signup and view all the answers

What is the primary mechanism of action of circulating antibodies in myasthenia gravis?

Blocking acetylcholine receptors at the postsynaptic neuromuscular junction (C) Signup and view all the answers

What is the purpose of administering edrophonium chloride in the diagnosis of myasthenia gravis?

To increase the levels of acetylcholine at the neuromuscular junction (D) Signup and view all the answers

What is the primary therapeutic application of scopolamine?

Treatment of motion sickness (C) Signup and view all the answers

What is the primary action of cholinesterase inhibitors in the treatment of myasthenia gravis?

Directly improving muscle function (A) Signup and view all the answers

What is the primary mechanism of action of parasympatholytics?

Blocking the actions of acetylcholine at the muscarinic receptors (D) Signup and view all the answers

What is the primary nursing implication related to the use of parasympatholytic drugs?

Monitoring for anticholinergic side effects (C) Signup and view all the answers

What is the therapeutic application of Pilocarpine?

Lowering of IOP in chronic simple glaucoma (C) Signup and view all the answers

What is the reason why acetylcholine is therapeutically of no importance?

It has a multiplicity of actions (A) Signup and view all the answers

Which drug is used to treat conditions associated with increased muscle tone?

Botulinum toxin (B) Signup and view all the answers

What is the mechanism of action of Botulinum toxin?

Inhibition of ACh release (D) Signup and view all the answers

What is the primary effect of pilocarpine on the eye when applied topically?

Miosis and contraction of the ciliary body (D) Signup and view all the answers

Which drug is used to relieve abdominal pain in colics?

Buscopan (A) Signup and view all the answers

What is the primary use of neostigmine in medical therapy?

To treat myasthenia gravis (B) Signup and view all the answers

What is the therapeutic application of Scopolamine?

Motion sickness and relieve spasms and colics (B) Signup and view all the answers

What is the primary adverse effect of pilocarpine hydrochloride 1% ophthalmic solution?

Spasm of accommodation (C) Signup and view all the answers