Ocular Cholinergic Agonists and Antagonists
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Questions and Answers

Which drug is primarily used as an alternative treatment when allergic reactions to atropine occur?

  • Homatropine
  • Physostigmine
  • Scopolamine (correct)
  • Cyclopentolate

What is the main clinical use of Homatropine?

  • Treatment of allommodative esotropia
  • IOP reduction
  • Cycloplegic refraction
  • Treatment of iridocyclitis (correct)

In terms of potency compared to atropine, how potent is Homatropine?

  • Three times more potent than atropine
  • 2 times more potent than atropine
  • 1/10 as potent as atropine (correct)
  • Equivalent potency to atropine

Which drug has a mydriatic and cycloplegic effect that lasts approximately 24 hours?

<p>Cyclopentolate (B)</p> Signup and view all the answers

What is the main reason Scopolamine is not a drug of choice?

<p>Toxicity (B)</p> Signup and view all the answers

Among the listed drugs, which one is specifically mentioned to be associated with Superficial Punctate Keratitis and Contact Dermatitis as ocular side effects?

<p>Cyclopentolate (C)</p> Signup and view all the answers

What is the clinical use of Atropine for the eye?

<p>Treatment of myopia (C)</p> Signup and view all the answers

What are the ocular side effects associated with Atropine?

<p>Contact dermatitis (B)</p> Signup and view all the answers

What is the lethal dosage of Atropine in children aged 6-12 years old?

<p>10mg (C)</p> Signup and view all the answers

What are the initial signs of Atropine toxicity in the body?

<p>Dryness of mouth and skin (D)</p> Signup and view all the answers

What is the specific antidote for Atropine toxicity?

<p>Physostigmine (D)</p> Signup and view all the answers

What is a systemic side effect of Atropine on the central nervous system?

<p>Delirium and hallucinations (C)</p> Signup and view all the answers

Which neurotransmitter is responsible for both pre and post-ganglionic synapse in the efferent oculo-parasympathetic pathway?

<p>Acetylcholine (C)</p> Signup and view all the answers

What is the function of M3 receptors in the post-ganglionic effector structures of the oculo-parasympathetic pathway?

<p>Contraction of the iris (A)</p> Signup and view all the answers

Which type of medication is pilocarpine classified as in the pharmacological treatment categories?

<p>Cholinergic agonist (C)</p> Signup and view all the answers

What autoimmune disorder affects voltage-gated calcium channels on the pre-synaptic membrane of the nerve-muscle neuromuscular junction?

<p>Lambert-Eaton Myasthenic Syndrome (LEMS) (D)</p> Signup and view all the answers

Which medication is commonly used as a parasympatholytic and cycloplegic/cyclomydriatic agent?

<p>Atropine (A)</p> Signup and view all the answers

What is the primary effect of Lambert-Eaton Myasthenic Syndrome (LEMS) on the neuromuscular junction?

<p>Prevents acetylcholine release (D)</p> Signup and view all the answers

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