Ocular Cholinergic Agonists and Antagonists

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CharitableBalalaika
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18 Questions

Which drug is primarily used as an alternative treatment when allergic reactions to atropine occur?

Scopolamine

What is the main clinical use of Homatropine?

Treatment of iridocyclitis

In terms of potency compared to atropine, how potent is Homatropine?

1/10 as potent as atropine

Which drug has a mydriatic and cycloplegic effect that lasts approximately 24 hours?

Cyclopentolate

What is the main reason Scopolamine is not a drug of choice?

Toxicity

Among the listed drugs, which one is specifically mentioned to be associated with Superficial Punctate Keratitis and Contact Dermatitis as ocular side effects?

Cyclopentolate

What is the clinical use of Atropine for the eye?

Treatment of myopia

What are the ocular side effects associated with Atropine?

Contact dermatitis

What is the lethal dosage of Atropine in children aged 6-12 years old?

10mg

What are the initial signs of Atropine toxicity in the body?

Dryness of mouth and skin

What is the specific antidote for Atropine toxicity?

Physostigmine

What is a systemic side effect of Atropine on the central nervous system?

Delirium and hallucinations

Which neurotransmitter is responsible for both pre and post-ganglionic synapse in the efferent oculo-parasympathetic pathway?

Acetylcholine

What is the function of M3 receptors in the post-ganglionic effector structures of the oculo-parasympathetic pathway?

Contraction of the iris

Which type of medication is pilocarpine classified as in the pharmacological treatment categories?

Cholinergic agonist

What autoimmune disorder affects voltage-gated calcium channels on the pre-synaptic membrane of the nerve-muscle neuromuscular junction?

Lambert-Eaton Myasthenic Syndrome (LEMS)

Which medication is commonly used as a parasympatholytic and cycloplegic/cyclomydriatic agent?

Atropine

What is the primary effect of Lambert-Eaton Myasthenic Syndrome (LEMS) on the neuromuscular junction?

Prevents acetylcholine release

Test your knowledge on ocular cholinergic agonists (parasympathomimetics) and antagonists (parasympatholytics/cycloplegics/cyclomydriatics) with this quiz focusing on Efferent Oculo-parasympathetic Pathway, neurotransmitters, innervation, and effector structures. Learn from the expertise of Jose M De Jesus, OD, MD, MA, FAAO.

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